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Protein

Bacterial non-heme ferritin

Gene

ftnA

Organism
Bacteroides fragilis (strain YCH46)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May alleviate iron toxicity in the presence of oxygen.

Catalytic activityi

4 Fe2+ + O2 + 6 H2O = 4 (FeO(OH)) + 8 H+.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi17Iron 1PROSITE-ProRule annotation1
Metal bindingi50Iron 1PROSITE-ProRule annotation1
Metal bindingi50Iron 2PROSITE-ProRule annotation1
Metal bindingi53Iron 1PROSITE-ProRule annotation1
Metal bindingi94Iron 2PROSITE-ProRule annotation1
Metal bindingi127Iron 2PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processIron storage
LigandIron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Bacterial non-heme ferritin (EC:1.16.3.2)
Gene namesi
Name:ftnA
Ordered Locus Names:BF3048
OrganismiBacteroides fragilis (strain YCH46)
Taxonomic identifieri295405 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
Proteomesi
  • UP000002197 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002010981 – 159Bacterial non-heme ferritinAdd BLAST159

Interactioni

Subunit structurei

Homooligomer of 24 subunits that assemble into a spherical protein shell (12 +/- 1 nM diameter) that can sequester at least 2000 iron atoms.By similarity

Structurei

3D structure databases

ProteinModelPortaliP0CJ83
SMRiP0CJ83
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 145Ferritin-like diironPROSITE-ProRule annotationAdd BLAST145

Sequence similaritiesi

Belongs to the ferritin family. Prokaryotic subfamily.Curated

Phylogenomic databases

HOGENOMiHOG000223382
KOiK02217
OMAiCEDKGFE
OrthoDBiPOG091H049F

Family and domain databases

Gene3Di1.20.1260.10, 1 hit
InterProiView protein in InterPro
IPR001519 Ferritin
IPR012347 Ferritin-like
IPR009040 Ferritin-like_diiron
IPR009078 Ferritin-like_SF
IPR008331 Ferritin_DPS_dom
PANTHERiPTHR11431 PTHR11431, 1 hit
PfamiView protein in Pfam
PF00210 Ferritin, 1 hit
SUPFAMiSSF47240 SSF47240, 1 hit
PROSITEiView protein in PROSITE
PS50905 FERRITIN_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

P0CJ83-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MISEKLQNAI NEQISAEMWS SNLYLSMSFY FEREGFSGFA HWMKKQSQEE
60 70 80 90 100
MGHAYAMADY IIKRGGIAKV DKIDVVPTGW GTPLEVFEHV FEHERHVSKL
110 120 130 140 150
VDALVDIAAA EKDKATQDFL WGFVREQVEE EATAQGIVDK IKRAGDAGIF

FIDSQLGQR
Length:159
Mass (Da):18,064
Last modified:February 8, 2011 - v1
Checksum:i3CAD5FC4984A0AB9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006841 Genomic DNA Translation: BAD49794.1
RefSeqiWP_005788812.1, NC_006347.1
YP_100328.1, NC_006347.1

Genome annotation databases

EnsemblBacteriaiBAD49794; BAD49794; BF3048
GeneIDi3083244
KEGGibfr:BF3048
PATRICifig|295405.11.peg.2916

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006841 Genomic DNA Translation: BAD49794.1
RefSeqiWP_005788812.1, NC_006347.1
YP_100328.1, NC_006347.1

3D structure databases

ProteinModelPortaliP0CJ83
SMRiP0CJ83
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD49794; BAD49794; BF3048
GeneIDi3083244
KEGGibfr:BF3048
PATRICifig|295405.11.peg.2916

Phylogenomic databases

HOGENOMiHOG000223382
KOiK02217
OMAiCEDKGFE
OrthoDBiPOG091H049F

Family and domain databases

Gene3Di1.20.1260.10, 1 hit
InterProiView protein in InterPro
IPR001519 Ferritin
IPR012347 Ferritin-like
IPR009040 Ferritin-like_diiron
IPR009078 Ferritin-like_SF
IPR008331 Ferritin_DPS_dom
PANTHERiPTHR11431 PTHR11431, 1 hit
PfamiView protein in Pfam
PF00210 Ferritin, 1 hit
SUPFAMiSSF47240 SSF47240, 1 hit
PROSITEiView protein in PROSITE
PS50905 FERRITIN_LIKE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiFTN_BACFR
AccessioniPrimary (citable) accession number: P0CJ83
Secondary accession number(s): P28733, Q9AEU4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 8, 2011
Last sequence update: February 8, 2011
Last modified: November 22, 2017
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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