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Protein

Speedy protein E6

Gene

SPDYE6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • protein kinase binding Source: GO_Central

Names & Taxonomyi

Protein namesi
Recommended name:
Speedy protein E6
Gene namesi
Name:SPDYE6
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000260097.2
HGNCiHGNC:35465 SPDYE6
neXtProtiNX_P0CI01

Pathology & Biotechi

Polymorphism and mutation databases

BioMutaiSPDYE6
DMDMi308191577

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003994781 – 402Speedy protein E6Add BLAST402

Proteomic databases

PRIDEiP0CI01
ProteomicsDBi52479

PTM databases

iPTMnetiP0CI01
PhosphoSitePlusiP0CI01

Expressioni

Gene expression databases

BgeeiENSG00000260097 Expressed in 92 organ(s), highest expression level in testis

Organism-specific databases

HPAiHPA051750

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiP0CI01, 4 interactors

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi275 – 363Arg-richAdd BLAST89

Sequence similaritiesi

Belongs to the Speedy/Ringo family.Curated

Phylogenomic databases

eggNOGiENOG410IX6P Eukaryota
ENOG41119TB LUCA
GeneTreeiENSGT00420000029723
InParanoidiP0CI01
KOiK08694
OMAiHSIRWRA
OrthoDBiEOG091G0MC6
PhylomeDBiP0CI01

Family and domain databases

InterProiView protein in InterPro
IPR020984 Speedy
PANTHERiPTHR31156 PTHR31156, 2 hits
PfamiView protein in Pfam
PF11357 Spy1, 2 hits

Sequencei

Sequence statusi: Complete.

P0CI01-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDRTETRFRK RGQITGKITT SRQPHPQNEQ SPQRSTSGYP LQEVVDDEML
60 70 80 90 100
GPSAPGVDPS PPCRSLGWKR KREWSDESEE EPEKELAPEP EETWVVEMLC
110 120 130 140 150
GLKMKLKQQR VSSILPEHHK DFNSQLAPGV DPSPPHRSFC WKRKMEWWDE
160 170 180 190 200
SEESLEEEPR KVLAPEPEEI WVAEMLCGLK MKLKRRRVSL VLPEHHEAFN
210 220 230 240 250
RLLEDPVIKR FLAWDKDLRV SDKYLLAMVI AYFSRAGFPS WQYQRIHFFL
260 270 280 290 300
ALYLANDMEE DDEDSKQNIF HFLYRKNRSR IPLLRKRWFQ LGHSMNPRAR
310 320 330 340 350
KNRSRIPLLR KRRFQLYRST NPRARKNRSR IPLLRKHRFQ LYRSMNSRAR
360 370 380 390 400
KNRSQIVLFQ KRRFHFFCSM SCRAWVSPEE LEEIQAYDPE HWVWARDRAH

LS
Length:402
Mass (Da):48,330
Last modified:March 28, 2018 - v2
Checksum:i8836BD49E5062B0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091390 Genomic DNA No translation available.
CCDSiCCDS78265.1
RefSeqiNP_001139682.2, NM_001146210.2
UniGeneiHs.489449

Genome annotation databases

EnsembliENST00000563237; ENSP00000485230; ENSG00000260097
GeneIDi729597
KEGGihsa:729597

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091390 Genomic DNA No translation available.
CCDSiCCDS78265.1
RefSeqiNP_001139682.2, NM_001146210.2
UniGeneiHs.489449

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP0CI01, 4 interactors

PTM databases

iPTMnetiP0CI01
PhosphoSitePlusiP0CI01

Polymorphism and mutation databases

BioMutaiSPDYE6
DMDMi308191577

Proteomic databases

PRIDEiP0CI01
ProteomicsDBi52479

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000563237; ENSP00000485230; ENSG00000260097
GeneIDi729597
KEGGihsa:729597

Organism-specific databases

CTDi729597
EuPathDBiHostDB:ENSG00000260097.2
GeneCardsiSPDYE6
HGNCiHGNC:35465 SPDYE6
HPAiHPA051750
neXtProtiNX_P0CI01
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IX6P Eukaryota
ENOG41119TB LUCA
GeneTreeiENSGT00420000029723
InParanoidiP0CI01
KOiK08694
OMAiHSIRWRA
OrthoDBiEOG091G0MC6
PhylomeDBiP0CI01

Miscellaneous databases

GenomeRNAii729597
PROiPR:P0CI01

Gene expression databases

BgeeiENSG00000260097 Expressed in 92 organ(s), highest expression level in testis

Family and domain databases

InterProiView protein in InterPro
IPR020984 Speedy
PANTHERiPTHR31156 PTHR31156, 2 hits
PfamiView protein in Pfam
PF11357 Spy1, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiSPDE6_HUMAN
AccessioniPrimary (citable) accession number: P0CI01
Secondary accession number(s): A0A096LNU6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: March 28, 2018
Last modified: November 7, 2018
This is version 46 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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