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Protein

Zinc finger CCHC domain-containing protein 18

Gene

ZCCHC18

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri347 – 364CCHC-typeAdd BLAST18

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger CCHC domain-containing protein 18Curated
Gene namesi
Name:ZCCHC18Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000166707.10
HGNCiHGNC:32459 ZCCHC18
neXtProtiNX_P0CG32

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000166707
PharmGKBiPA162409569

Polymorphism and mutation databases

DMDMi300681209

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003953611 – 403Zinc finger CCHC domain-containing protein 18Add BLAST403

Proteomic databases

PeptideAtlasiP0CG32
PRIDEiP0CG32
ProteomicsDBi52462

PTM databases

PhosphoSitePlusiP0CG32

Expressioni

Gene expression databases

BgeeiENSG00000166707 Expressed in 120 organ(s), highest expression level in cerebellum
GenevisibleiP0CG32 HS

Organism-specific databases

HPAiHPA034940

Interactioni

Protein-protein interaction databases

BioGridi569537, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliP0CG32
SMRiP0CG32
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ZCCHC12 family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri347 – 364CCHC-typeAdd BLAST18

Keywords - Domaini

Zinc-finger

Phylogenomic databases

GeneTreeiENSGT00530000062986
InParanoidiP0CG32
OMAiRSEPIME
OrthoDBiEOG091G0AM8
PhylomeDBiP0CG32

Family and domain databases

InterProiView protein in InterPro
IPR026523 PNMA
PANTHERiPTHR23095 PTHR23095, 1 hit
PfamiView protein in Pfam
PF14893 PNMA, 1 hit

Sequencei

Sequence statusi: Complete.

P0CG32-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASITACVGN SRQQNAPLPP WAHSMLRSLG RSLCPLVVKM AERNMKLFSG
60 70 80 90 100
RVVPAQGKET FENWLIQVNE VLPDWSMSEE EKLKRLMKTL RGPAREVMRL
110 120 130 140 150
LQAANPNLSV ADFLRAMKLV FGESESSVTA HGKFFNTLQA QGEKASLYVI
160 170 180 190 200
RLEVQLQNAI QAGILAEKDA NQTRLQQLLL GAELNRDLRF RLKHLLRMYA
210 220 230 240 250
NKQERLPNFL ELIKMIREEE DWDDAFIKRK RPKRSEPIME RAASPVAFQG
260 270 280 290 300
AQPIAISSAD CNCNVIEIDD TLDDSDEDVI LVVSLYPSLT PTGAPPFRGR
310 320 330 340 350
ARPLDQVLVI DSPNNSGAQS LSTSGGSGYK NDGPGNIRRA RKRKYTTRCS
360 370 380 390 400
YCGEEGHSKE TCDNESNKAQ VFENLIITLQ ELTHTEERSK EVPGEHSDAS

EPQ
Length:403
Mass (Da):45,160
Last modified:July 13, 2010 - v1
Checksum:iF2194FBF417DB209
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z82254 Genomic DNA No translation available.
CCDSiCCDS65304.1
RefSeqiNP_001137450.1, NM_001143978.2
XP_011529314.1, XM_011531012.2
UniGeneiHs.648338

Genome annotation databases

EnsembliENST00000537356; ENSP00000473824; ENSG00000166707
ENST00000611638; ENSP00000482195; ENSG00000166707
GeneIDi644353
KEGGihsa:644353
UCSCiuc011msh.4 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z82254 Genomic DNA No translation available.
CCDSiCCDS65304.1
RefSeqiNP_001137450.1, NM_001143978.2
XP_011529314.1, XM_011531012.2
UniGeneiHs.648338

3D structure databases

ProteinModelPortaliP0CG32
SMRiP0CG32
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi569537, 1 interactor

PTM databases

PhosphoSitePlusiP0CG32

Polymorphism and mutation databases

DMDMi300681209

Proteomic databases

PeptideAtlasiP0CG32
PRIDEiP0CG32
ProteomicsDBi52462

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000537356; ENSP00000473824; ENSG00000166707
ENST00000611638; ENSP00000482195; ENSG00000166707
GeneIDi644353
KEGGihsa:644353
UCSCiuc011msh.4 human

Organism-specific databases

CTDi644353
EuPathDBiHostDB:ENSG00000166707.10
GeneCardsiZCCHC18
HGNCiHGNC:32459 ZCCHC18
HPAiHPA034940
neXtProtiNX_P0CG32
OpenTargetsiENSG00000166707
PharmGKBiPA162409569
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00530000062986
InParanoidiP0CG32
OMAiRSEPIME
OrthoDBiEOG091G0AM8
PhylomeDBiP0CG32

Miscellaneous databases

GenomeRNAii644353
PROiPR:P0CG32

Gene expression databases

BgeeiENSG00000166707 Expressed in 120 organ(s), highest expression level in cerebellum
GenevisibleiP0CG32 HS

Family and domain databases

InterProiView protein in InterPro
IPR026523 PNMA
PANTHERiPTHR23095 PTHR23095, 1 hit
PfamiView protein in Pfam
PF14893 PNMA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiZCC18_HUMAN
AccessioniPrimary (citable) accession number: P0CG32
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 13, 2010
Last sequence update: July 13, 2010
Last modified: November 7, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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