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Protein

NHL-repeat-containing protein 4

Gene

NHLRC4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
NHL-repeat-containing protein 4
Gene namesi
Name:NHLRC4
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000257108.1
HGNCiHGNC:26700 NHLRC4
neXtProtiNX_P0CG21

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA165450302

Polymorphism and mutation databases

BioMutaiNHLRC4

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003951061 – 123NHL-repeat-containing protein 4Add BLAST123

Proteomic databases

PaxDbiP0CG21
PRIDEiP0CG21
ProteomicsDBi52455

Expressioni

Gene expression databases

BgeeiENSG00000257108 Expressed in 106 organ(s), highest expression level in right uterine tube
GenevisibleiP0CG21 HS

Interactioni

Protein-protein interaction databases

IntActiP0CG21, 15 interactors
STRINGi9606.ENSP00000410858

Structurei

3D structure databases

ProteinModelPortaliP0CG21
SMRiP0CG21
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati35 – 78NHL 1Add BLAST44
Repeati79 – 119NHL 2Add BLAST41

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG2177 Eukaryota
ENOG4111G04 LUCA
GeneTreeiENSGT00900000141088
HOGENOMiHOG000133029
InParanoidiP0CG21
OMAiWLFGSAC
OrthoDBiEOG091G0SQX
PhylomeDBiP0CG21

Family and domain databases

Gene3Di2.120.10.30, 1 hit
InterProiView protein in InterPro
IPR011042 6-blade_b-propeller_TolB-like
IPR001258 NHL_repeat
IPR013017 NHL_repeat_subgr
PfamiView protein in Pfam
PF01436 NHL, 1 hit
PROSITEiView protein in PROSITE
PS51125 NHL, 2 hits

Sequencei

Sequence statusi: Complete.

P0CG21-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLGLEGPCWV GPGPDGGLAV SEEFGDVRLF GSARQPLGSL GGWTGHTFGC
60 70 80 90 100
PAGICSNSEG NVIVADEQRR QVTLFPRAGP PICLVSEGLG QPLGVACAPQ
110 120
GQLLVADAKD NSIKVYQGLK ELA
Length:123
Mass (Da):12,631
Last modified:June 15, 2010 - v1
Checksum:i0AA4CBDBF7CD9074
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093527 mRNA Translation: BAC04193.1
Z98883 Genomic DNA No translation available.
BC113527 mRNA Translation: AAI13528.1
BC113529 mRNA Translation: AAI13530.1
CCDSiCCDS45366.1
RefSeqiNP_001288088.1, NM_001301159.1
NP_788850.1, NM_176677.2
UniGeneiHs.664267
Hs.744949

Genome annotation databases

EnsembliENST00000424439; ENSP00000410858; ENSG00000257108
ENST00000540585; ENSP00000442223; ENSG00000257108
GeneIDi283948
KEGGihsa:283948
UCSCiuc002chl.4 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093527 mRNA Translation: BAC04193.1
Z98883 Genomic DNA No translation available.
BC113527 mRNA Translation: AAI13528.1
BC113529 mRNA Translation: AAI13530.1
CCDSiCCDS45366.1
RefSeqiNP_001288088.1, NM_001301159.1
NP_788850.1, NM_176677.2
UniGeneiHs.664267
Hs.744949

3D structure databases

ProteinModelPortaliP0CG21
SMRiP0CG21
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP0CG21, 15 interactors
STRINGi9606.ENSP00000410858

Polymorphism and mutation databases

BioMutaiNHLRC4

Proteomic databases

PaxDbiP0CG21
PRIDEiP0CG21
ProteomicsDBi52455

Protocols and materials databases

DNASUi283948
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000424439; ENSP00000410858; ENSG00000257108
ENST00000540585; ENSP00000442223; ENSG00000257108
GeneIDi283948
KEGGihsa:283948
UCSCiuc002chl.4 human

Organism-specific databases

CTDi283948
EuPathDBiHostDB:ENSG00000257108.1
GeneCardsiNHLRC4
HGNCiHGNC:26700 NHLRC4
neXtProtiNX_P0CG21
PharmGKBiPA165450302
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2177 Eukaryota
ENOG4111G04 LUCA
GeneTreeiENSGT00900000141088
HOGENOMiHOG000133029
InParanoidiP0CG21
OMAiWLFGSAC
OrthoDBiEOG091G0SQX
PhylomeDBiP0CG21

Miscellaneous databases

GenomeRNAii283948
PROiPR:P0CG21

Gene expression databases

BgeeiENSG00000257108 Expressed in 106 organ(s), highest expression level in right uterine tube
GenevisibleiP0CG21 HS

Family and domain databases

Gene3Di2.120.10.30, 1 hit
InterProiView protein in InterPro
IPR011042 6-blade_b-propeller_TolB-like
IPR001258 NHL_repeat
IPR013017 NHL_repeat_subgr
PfamiView protein in Pfam
PF01436 NHL, 1 hit
PROSITEiView protein in PROSITE
PS51125 NHL, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiNHLC4_HUMAN
AccessioniPrimary (citable) accession number: P0CG21
Secondary accession number(s): B8ZZ27
, Q8N233, Q96AX3, Q96S23
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: June 15, 2010
Last modified: November 7, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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