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Protein

Proline-rich protein 35

Gene

PRR35

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Proline-rich protein 35
Alternative name(s):
Uncharacterized protein RJD1
Gene namesi
Name:PRR35
Synonyms:C16orf11
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000161992.5
HGNCiHGNC:14139 PRR35
neXtProtiNX_P0CG20

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000161992
PharmGKBiPA25524

Polymorphism and mutation databases

BioMutaiC16orf11
DMDMi298351619

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003261841 – 571Proline-rich protein 35Add BLAST571

Proteomic databases

PaxDbiP0CG20
PeptideAtlasiP0CG20
PRIDEiP0CG20
ProteomicsDBi52454

PTM databases

iPTMnetiP0CG20
PhosphoSitePlusiP0CG20

Expressioni

Gene expression databases

BgeeiENSG00000161992 Expressed in 29 organ(s), highest expression level in right hemisphere of cerebellum
GenevisibleiP0CG20 HS

Organism-specific databases

HPAiHPA069297

Interactioni

Protein-protein interaction databases

BioGridi126978, 1 interactor
IntActiP0CG20, 73 interactors
STRINGi9606.ENSP00000386499

Structurei

3D structure databases

ProteinModelPortaliP0CG20
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi83 – 401Pro-richAdd BLAST319

Phylogenomic databases

eggNOGiENOG410IG6R Eukaryota
ENOG410YD4G LUCA
GeneTreeiENSGT00530000063870
HOGENOMiHOG000089960
InParanoidiP0CG20
OMAiSGHTTKC
OrthoDBiEOG091G036R
PhylomeDBiP0CG20
TreeFamiTF331381

Family and domain databases

InterProiView protein in InterPro
IPR039363 ZNF750
IPR039064 ZNF750_Znf
PANTHERiPTHR14678 PTHR14678, 1 hit
PfamiView protein in Pfam
PF15269 zf-C2H2_7, 1 hit

Sequencei

Sequence statusi: Complete.

P0CG20-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSREAGSCRV GTGARARSRK PKKPHYIPRP WGKPYNYKCF QCPFTCLEKS
60 70 80 90 100
HLYNHMKYSL CKDSLSLLLD SPDWACRRGS TTPRPHAPTP DRPGESDPGR
110 120 130 140 150
QPQGARPTGA APAPDLVVAD IHSLHCGGGP KSRAKGSPGP PPPVARATRK
160 170 180 190 200
GPGPSGLLPE SWKPGMGGDP RGVGAGDMAS AGPEGSVPCY PPPAPGEFPE
210 220 230 240 250
AHSLHLSLLG VNYPLSPGLF SYLGPSLAAA AHVPFLASAS PLLPPATAFP
260 270 280 290 300
AVQPPQRPTP APRLYYPLLL EHTLGLPAGK AALAKAPVSP RSPSGTPAPG
310 320 330 340 350
LLKVPVPGLG PWPRVTPRDP GQEGELERAA QSDPRRRLSL GSRLELPKAS
360 370 380 390 400
PSLTRFCSRS SLPTGSSVML WPEDGDPGGP ETPGPEGPLP LQPRGPVPGS
410 420 430 440 450
PEHVGEDLTR ALGDYARVEQ RLGQLGPAGG LAPRPLREQL GKIRLELLTI
460 470 480 490 500
HQALEQAVRP PDAPLDLSVK RAPAKGPQAL GEAWGRPELG PVLTGGTPEP
510 520 530 540 550
PGMLGPAAPQ PFSGHTTKCE ADSSVPPPGL PLAAPDDPVI PGSGWGTCVA
560 570
TRSSQTPEAV CGLQSPQGAE V
Length:571
Mass (Da):59,354
Last modified:June 15, 2010 - v1
Checksum:i7F15F84F05FF460E
GO

Sequence cautioni

The sequence AAK61234 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006464 Genomic DNA Translation: AAK61234.1 Sequence problems.
Z97986 Genomic DNA No translation available.
CH471112 Genomic DNA Translation: EAW85802.1
BC016613 mRNA Translation: AAH16613.1
CCDSiCCDS45365.1
RefSeqiNP_660313.1, NM_145270.2
XP_016878448.1, XM_017022959.1
XP_016878449.1, XM_017022960.1
UniGeneiHs.632220

Genome annotation databases

EnsembliENST00000409413; ENSP00000386499; ENSG00000161992
GeneIDi146325
KEGGihsa:146325
UCSCiuc002chk.4 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006464 Genomic DNA Translation: AAK61234.1 Sequence problems.
Z97986 Genomic DNA No translation available.
CH471112 Genomic DNA Translation: EAW85802.1
BC016613 mRNA Translation: AAH16613.1
CCDSiCCDS45365.1
RefSeqiNP_660313.1, NM_145270.2
XP_016878448.1, XM_017022959.1
XP_016878449.1, XM_017022960.1
UniGeneiHs.632220

3D structure databases

ProteinModelPortaliP0CG20
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126978, 1 interactor
IntActiP0CG20, 73 interactors
STRINGi9606.ENSP00000386499

PTM databases

iPTMnetiP0CG20
PhosphoSitePlusiP0CG20

Polymorphism and mutation databases

BioMutaiC16orf11
DMDMi298351619

Proteomic databases

PaxDbiP0CG20
PeptideAtlasiP0CG20
PRIDEiP0CG20
ProteomicsDBi52454

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000409413; ENSP00000386499; ENSG00000161992
GeneIDi146325
KEGGihsa:146325
UCSCiuc002chk.4 human

Organism-specific databases

CTDi146325
EuPathDBiHostDB:ENSG00000161992.5
GeneCardsiPRR35
HGNCiHGNC:14139 PRR35
HPAiHPA069297
neXtProtiNX_P0CG20
OpenTargetsiENSG00000161992
PharmGKBiPA25524
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IG6R Eukaryota
ENOG410YD4G LUCA
GeneTreeiENSGT00530000063870
HOGENOMiHOG000089960
InParanoidiP0CG20
OMAiSGHTTKC
OrthoDBiEOG091G036R
PhylomeDBiP0CG20
TreeFamiTF331381

Miscellaneous databases

GenomeRNAii146325
PROiPR:P0CG20

Gene expression databases

BgeeiENSG00000161992 Expressed in 29 organ(s), highest expression level in right hemisphere of cerebellum
GenevisibleiP0CG20 HS

Family and domain databases

InterProiView protein in InterPro
IPR039363 ZNF750
IPR039064 ZNF750_Znf
PANTHERiPTHR14678 PTHR14678, 1 hit
PfamiView protein in Pfam
PF15269 zf-C2H2_7, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPRR35_HUMAN
AccessioniPrimary (citable) accession number: P0CG20
Secondary accession number(s): B8ZZ27
, Q8N233, Q96AX3, Q96S23
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: June 15, 2010
Last modified: November 7, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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