UniProtKB - P0CF97 (F200B_HUMAN)
Protein
Protein FAM200B
Gene
FAM200B
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Protein FAM200BCurated |
Gene namesi | |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:27740, FAM200B |
neXtProti | NX_P0CF97 |
VEuPathDBi | HostDB:ENSG00000237765.6 |
Pathology & Biotechi
Organism-specific databases
DisGeNETi | 285550 |
OpenTargetsi | ENSG00000237765 |
PharmGKBi | PA165664101 |
Miscellaneous databases
Pharosi | P0CF97, Tdark |
Genetic variation databases
BioMutai | FAM200B |
DMDMi | 296439620 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000394262 | 1 – 657 | Protein FAM200BAdd BLAST | 657 |
Proteomic databases
MassIVEi | P0CF97 |
PaxDbi | P0CF97 |
PeptideAtlasi | P0CF97 |
PRIDEi | P0CF97 |
ProteomicsDBi | 52445 |
PTM databases
iPTMneti | P0CF97 |
PhosphoSitePlusi | P0CF97 |
Expressioni
Gene expression databases
Bgeei | ENSG00000237765, Expressed in muscle tissue and 218 other tissues |
ExpressionAtlasi | P0CF97, baseline and differential |
Genevisiblei | P0CF97, HS |
Organism-specific databases
HPAi | ENSG00000237765, Low tissue specificity |
Interactioni
Protein-protein interaction databases
BioGRIDi | 130142, 2 interactors |
STRINGi | 9606.ENSP00000483930 |
Miscellaneous databases
RNActi | P0CF97, protein |
Family & Domainsi
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 21 – 24 | Poly-Ser | 4 | |
Compositional biasi | 54 – 57 | Poly-Lys | 4 | |
Compositional biasi | 600 – 603 | Poly-Leu | 4 |
Sequence similaritiesi
Belongs to the FAM200 family.Curated
Phylogenomic databases
eggNOGi | ENOG502QT83, Eukaryota |
GeneTreei | ENSGT00940000164387 |
HOGENOMi | CLU_021316_5_0_1 |
InParanoidi | P0CF97 |
OMAi | RICTIAE |
OrthoDBi | 875619at2759 |
PhylomeDBi | P0CF97 |
TreeFami | TF328297 |
Family and domain databases
InterProi | View protein in InterPro IPR012337, RNaseH-like_sf |
SUPFAMi | SSF53098, SSF53098, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
P0CF97-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDHFFIKRKR NSEVKYTEAC SSSSVESGIV NSDNIEKNTD SNLQTSTSFE
60 70 80 90 100
PHFKKKKVSA RRYNEDYLKY GFIKCEKPFE NDRPQCVICN NILANESLKP
110 120 130 140 150
SKLKRHLETQ HAELIDKPLE YFQRKKKDIK LSTQFLSCST AVSEKALLSS
160 170 180 190 200
YLVAYRVAKE KIANTAAEKI ILPACLDMVR TIFDDKSADK LKTIPNDNTV
210 220 230 240 250
SLRICTIAEH LETMLITRLQ SGIDFAIQLD ESTDIGSCTT LLVYVRYAWQ
260 270 280 290 300
DDFLEDFLCF LNLTSHLSGL DIFTELERRI VGQYKLNWKN CKGITSDGTA
310 320 330 340 350
TMTGKHSRVI KKLLEVTNNG AVWNHCFIHR EGLASREIPQ NLMEVLKNAV
360 370 380 390 400
KVVNFIKGSS LNSRLLETFC SEIGTNHTHL LYHTKIRWLS QGKILSRVYE
410 420 430 440 450
LRNEIHFFLI EKKSHLASIF EDDTWVTKLA YLTDIFSILN ELSLKLQGKN
460 470 480 490 500
SDVFQHVERI QGFRKTLLLW QVRLKSNRPS YYMFPRFLQH IEENIINENI
510 520 530 540 550
LKEIKLEILL HLTSLSQTFN HFFPEEKFET LRENSWVKDP FAFRHPESII
560 570 580 590 600
ELNLVPEEEN ELLQLSSSYT LKNDYETLSL SAFWMKVKED FPLLSRKSVL
610 620 630 640 650
LLLPFTTTSL CELGFSILTQ LKTKERNGLN CAAVMRVALS SCVPDWNELM
NRQAHPS
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A6Q8PFA1 | A0A6Q8PFA1_HUMAN | Protein FAM200B | FAM200B | 56 | Annotation score: | ||
A0A6Q8PGG8 | A0A6Q8PGG8_HUMAN | Protein FAM200B | FAM200B | 63 | Annotation score: | ||
D6RAC6 | D6RAC6_HUMAN | Protein FAM200B | FAM200B | 24 | Annotation score: | ||
A0A6Q8PG77 | A0A6Q8PG77_HUMAN | Protein FAM200B | FAM200B | 161 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC114744 Genomic DNA No translation available. |
CCDSi | CCDS47028.1 |
RefSeqi | NP_001138663.1, NM_001145191.1 XP_016863537.1, XM_017008048.1 |
Genome annotation databases
Ensembli | ENST00000422728; ENSP00000393017; ENSG00000237765 |
GeneIDi | 285550 |
KEGGi | hsa:285550 |
UCSCi | uc003gof.5, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC114744 Genomic DNA No translation available. |
CCDSi | CCDS47028.1 |
RefSeqi | NP_001138663.1, NM_001145191.1 XP_016863537.1, XM_017008048.1 |
3D structure databases
SMRi | P0CF97 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 130142, 2 interactors |
STRINGi | 9606.ENSP00000483930 |
PTM databases
iPTMneti | P0CF97 |
PhosphoSitePlusi | P0CF97 |
Genetic variation databases
BioMutai | FAM200B |
DMDMi | 296439620 |
Proteomic databases
MassIVEi | P0CF97 |
PaxDbi | P0CF97 |
PeptideAtlasi | P0CF97 |
PRIDEi | P0CF97 |
ProteomicsDBi | 52445 |
Genome annotation databases
Ensembli | ENST00000422728; ENSP00000393017; ENSG00000237765 |
GeneIDi | 285550 |
KEGGi | hsa:285550 |
UCSCi | uc003gof.5, human |
Organism-specific databases
CTDi | 285550 |
DisGeNETi | 285550 |
GeneCardsi | FAM200B |
HGNCi | HGNC:27740, FAM200B |
HPAi | ENSG00000237765, Low tissue specificity |
neXtProti | NX_P0CF97 |
OpenTargetsi | ENSG00000237765 |
PharmGKBi | PA165664101 |
VEuPathDBi | HostDB:ENSG00000237765.6 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502QT83, Eukaryota |
GeneTreei | ENSGT00940000164387 |
HOGENOMi | CLU_021316_5_0_1 |
InParanoidi | P0CF97 |
OMAi | RICTIAE |
OrthoDBi | 875619at2759 |
PhylomeDBi | P0CF97 |
TreeFami | TF328297 |
Enzyme and pathway databases
PathwayCommonsi | P0CF97 |
Miscellaneous databases
BioGRID-ORCSi | 285550, 48 hits in 858 CRISPR screens |
ChiTaRSi | FAM200B, human |
GenomeRNAii | 285550 |
Pharosi | P0CF97, Tdark |
PROi | PR:P0CF97 |
RNActi | P0CF97, protein |
Gene expression databases
Bgeei | ENSG00000237765, Expressed in muscle tissue and 218 other tissues |
ExpressionAtlasi | P0CF97, baseline and differential |
Genevisiblei | P0CF97, HS |
Family and domain databases
InterProi | View protein in InterPro IPR012337, RNaseH-like_sf |
SUPFAMi | SSF53098, SSF53098, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F200B_HUMAN | |
Accessioni | P0CF97Primary (citable) accession number: P0CF97 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 18, 2010 |
Last sequence update: | May 18, 2010 | |
Last modified: | February 10, 2021 | |
This is version 65 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Human chromosome 4
Human chromosome 4: entries, gene names and cross-references to MIM