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Protein

T-cell receptor gamma chain C region 1

Gene

TRGC1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Keywordsi

Molecular functionReceptor

Names & Taxonomyi

Protein namesi
Recommended name:
T-cell receptor gamma chain C region 1
Gene namesi
Name:TRGC1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:12275 TRGC1
MIMi186970 gene
neXtProtiNX_P0CF51

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei139 – 161HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi6966

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000393472‹1 – 173T-cell receptor gamma chain C region 1Add BLAST›173

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi32 ↔ 88PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PeptideAtlasiP0CF51
PRIDEiP0CF51
ProteomicsDBi52442

PTM databases

iPTMnetiP0CF51
PhosphoSitePlusiP0CF51

Structurei

Secondary structure

1173
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP0CF51
SMRiP0CF51
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 104Ig-likeAdd BLAST95

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi143 – 147Poly-Leu5

Keywords - Domaini

Immunoglobulin domain, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiP0CF51
PhylomeDBiP0CF51

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003597 Ig_C1-set
PfamiView protein in Pfam
PF07654 C1-set, 1 hit
SMARTiView protein in SMART
SM00407 IGc1, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P0CF51-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
DKQLDADVSP KPTIFLPSIA ETKLQKAGTY LCLLEKFFPD VIKIHWQEKK
60 70 80 90 100
SNTILGSQEG NTMKTNDTYM KFSWLTVPEK SLDKEHRCIV RHENNKNGVD
110 120 130 140 150
QEIIFPPIKT DVITMDPKDN CSKDANDTLL LQLTNTSAYY MYLLLLLKSV
160 170
VYFAIITCCL LRRTAFCCNG EKS
Length:173
Mass (Da):19,804
Last modified:April 20, 2010 - v1
Checksum:i67C65AF5C03D33BB
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A075B6Q9A0A075B6Q9_HUMAN
T-cell receptor gamma chain C regio...
TRGC1
173Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M14998, M14996, M14997 Genomic DNA Translation: AAA75392.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M14998, M14996, M14997 Genomic DNA Translation: AAA75392.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4LFHX-ray2.30G1-129[»]
4LHUX-ray2.87G1-129[»]
ProteinModelPortaliP0CF51
SMRiP0CF51
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiP0CF51
PhosphoSitePlusiP0CF51

Proteomic databases

PeptideAtlasiP0CF51
PRIDEiP0CF51
ProteomicsDBi52442

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

DisGeNETi6966
GeneCardsiTRGC1
HGNCiHGNC:12275 TRGC1
MIMi186970 gene
neXtProtiNX_P0CF51
GenAtlasiSearch...

Phylogenomic databases

InParanoidiP0CF51
PhylomeDBiP0CF51

Miscellaneous databases

ChiTaRSiTRGC1 human
PROiPR:P0CF51
SOURCEiSearch...

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003597 Ig_C1-set
PfamiView protein in Pfam
PF07654 C1-set, 1 hit
SMARTiView protein in SMART
SM00407 IGc1, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTRGC1_HUMAN
AccessioniPrimary (citable) accession number: P0CF51
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: April 20, 2010
Last modified: June 20, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
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