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UniProtKB - P0CE70 (NFT1_YEASX)
Protein
ABC transporter NFT1
Gene
NFT1
Organism
Saccharomyces cerevisiae (Baker's yeast)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 686 – 693 | ATPPROSITE-ProRule annotation | 8 | |
Nucleotide bindingi | 1319 – 1326 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ABC-type transporter activity Source: InterPro
- ATP binding Source: UniProtKB-KW
Keywordsi
Biological process | Transport |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: ABC transporter NFT1Alternative name(s): New full-length MRP-type transporter 1 |
Gene namesi | Name:NFT1 |
Organismi | Saccharomyces cerevisiae (Baker's yeast) |
Taxonomic identifieri | 4932 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Organism-specific databases
VEuPathDBi | FungiDB:YKR103W FungiDB:YKR104W |
Subcellular locationi
Other locations
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 29 | ExtracellularSequence analysisAdd BLAST | 29 | |
Transmembranei | 30 – 50 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 51 – 103 | CytoplasmicSequence analysisAdd BLAST | 53 | |
Transmembranei | 104 – 124 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 125 – 130 | ExtracellularSequence analysis | 6 | |
Transmembranei | 131 – 151 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 152 – 169 | CytoplasmicSequence analysisAdd BLAST | 18 | |
Transmembranei | 170 – 190 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 191 – 201 | ExtracellularSequence analysisAdd BLAST | 11 | |
Transmembranei | 202 – 222 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 223 – 302 | CytoplasmicSequence analysisAdd BLAST | 80 | |
Transmembranei | 303 – 323 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 324 – 351 | ExtracellularSequence analysisAdd BLAST | 28 | |
Transmembranei | 352 – 374 | HelicalPROSITE-ProRule annotationAdd BLAST | 23 | |
Topological domaini | 375 – 449 | CytoplasmicSequence analysisAdd BLAST | 75 | |
Transmembranei | 450 – 470 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 471 – 481 | ExtracellularSequence analysisAdd BLAST | 11 | |
Transmembranei | 482 – 504 | HelicalPROSITE-ProRule annotationAdd BLAST | 23 | |
Topological domaini | 505 – 558 | CytoplasmicSequence analysisAdd BLAST | 54 | |
Transmembranei | 559 – 579 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 580 – 584 | ExtracellularSequence analysis | 5 | |
Transmembranei | 585 – 605 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 606 – 953 | CytoplasmicSequence analysisAdd BLAST | 348 | |
Transmembranei | 954 – 974 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 975 – 1013 | ExtracellularSequence analysisAdd BLAST | 39 | |
Transmembranei | 1014 – 1034 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 1035 – 1082 | CytoplasmicSequence analysisAdd BLAST | 48 | |
Transmembranei | 1083 – 1105 | HelicalPROSITE-ProRule annotationAdd BLAST | 23 | |
Topological domaini | 1106 – 1109 | ExtracellularSequence analysis | 4 | |
Transmembranei | 1110 – 1132 | HelicalPROSITE-ProRule annotationAdd BLAST | 23 | |
Topological domaini | 1133 – 1199 | CytoplasmicSequence analysisAdd BLAST | 67 | |
Transmembranei | 1200 – 1220 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 1221 – 1222 | ExtracellularSequence analysis | 2 | |
Transmembranei | 1223 – 1243 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 1244 – 1558 | CytoplasmicSequence analysisAdd BLAST | 315 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000392614 | 1 – 1558 | ABC transporter NFT1Add BLAST | 1558 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 4 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 311 – 621 | ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST | 311 | |
Domaini | 651 – 892 | ABC transporter 1PROSITE-ProRule annotationAdd BLAST | 242 | |
Domaini | 961 – 1251 | ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST | 291 | |
Domaini | 1285 – 1538 | ABC transporter 2PROSITE-ProRule annotationAdd BLAST | 254 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 410 – 434 | DisorderedSequence analysisAdd BLAST | 25 | |
Regioni | 892 – 926 | DisorderedSequence analysisAdd BLAST | 35 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 420 – 434 | Basic and acidic residuesSequence analysisAdd BLAST | 15 |
Sequence similaritiesi
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. [View classification]Curated
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixFamily and domain databases
Gene3Di | 1.20.1560.10, 2 hits 3.40.50.300, 2 hits |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR011527, ABC1_TM_dom IPR036640, ABC1_TM_sf IPR003439, ABC_transporter-like_ATP-bd IPR017871, ABC_transporter-like_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00664, ABC_membrane, 2 hits PF00005, ABC_tran, 2 hits |
SMARTi | View protein in SMART SM00382, AAA, 2 hits |
SUPFAMi | SSF52540, SSF52540, 2 hits SSF90123, SSF90123, 2 hits |
PROSITEi | View protein in PROSITE PS50929, ABC_TM1F, 2 hits PS00211, ABC_TRANSPORTER_1, 2 hits PS50893, ABC_TRANSPORTER_2, 2 hits |
i Sequence
Sequence statusi: Complete.
P0CE70-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIKNGTCPYW ERDDLSECAR REYIEFKFPL FILLTGMIYA FCKVFRAFYL
60 70 80 90 100
RGKNHTNEAP EFEEQGNGNH EYARFSVLRL KSAWESRSFC NVNNRSTFDK
110 120 130 140 150
FKKFIEGAFI VLQLTIHLYI LSSMPMDNKK FFHQGFLVQM FLWILLLVVI
160 170 180 190 200
TLRLISASQS FRWVLACKRD LWAVSFYSYA SLFTLSILPL RSVFIGKIKD
210 220 230 240 250
KIMVKYIISE TFIDLALLLL LSTSSIEGTR YSFLVENENK KLPPAPTVFG
260 270 280 290 300
LLTFSRIDRL IWKAYKHCLG NADIWDLDIN NKSIAILANF EMSSKKGRLL
310 320 330 340 350
PNIICYFKAV FISQLFLAFV SSFLNFVPSL LMPRILSYVN DPKSKSWNLV
360 370 380 390 400
SLYVSSMLVS KIIATTCRGQ GLFLGEKGTM QLRTVLISNI YSKTLRRTIL
410 420 430 440 450
KDSTTSLQKN ASTSFEENPD SSEAEPRKKS SRKDNSVNNV MSIDAFKVSE
460 470 480 490 500
AMNTFYLACE AVFMTVTALM ILYSLLGWSA FAGTFALLAM IPLNFWCATF
510 520 530 540 550
YGNYQADQLI LTDKRTSGIS EALNSIRVIK LLAWENLFYQ KIINVRDGEI
560 570 580 590 600
RLLKKKATIF FLNHLIWFFG PTLVSAITFS VFIKFQNQTL TPTIAFTALS
610 620 630 640 650
LFAILRTPMD QIASTVSLLI QSFISLERIQ DYLNESETRK YEILEQSNTK
660 670 680 690 700
FGFEDASMEW EAAETSFKLK NISIDFKLNS LNAIIGPTGS GKSSLLLGLL
710 720 730 740 750
GELNLLSGKI YVPTVESRDD LEIGKDGMTN SMAYCSQTPW LISGTIKDNV
760 770 780 790 800
VFGEIFNKQK FDDVMKSCCL DKDIKAMTAG IRTDVGDGGF SLSGGQQQRI
810 820 830 840 850
ALARAIYSSS RYLILDDCLS AVDPETALYI YEECLCGPMM KGRTCIITSH
860 870 880 890 900
NISLVTKRAD WLVILDRGEV KSQGKPSDLI KSNEFLRESI NNDSKNTTHN
910 920 930 940 950
QIDLKRSTTS KKTKNGDPEG GNSQDEVCAE VENFEETKME GSVKFSAYKW
960 970 980 990 1000
LADYFGGLGV VFVFTSSSIL IHGITLSQGF WLRYWLDTGS SGSKSTWLYR
1010 1020 1030 1040 1050
IVEGHSNIYF LLTYIIIGLV SSFLTSGKVW IAIISGTNVT KKIFAKLLSS
1060 1070 1080 1090 1100
ILYAKLRFHN VTPTGRIMNR FSKDMDIIDQ QLIPNFEGLS YSVVVCLWII
1110 1120 1130 1140 1150
LLIGYVTPQF LLFAIPLCAL YYTVCTLYLR ASRELKRIDN INISPIHQLF
1160 1170 1180 1190 1200
AEAIKGVTTI RALADERRFI TQSLVAIDRS NAPFFYLNMA TEWITYRVDI
1210 1220 1230 1240 1250
IGTLVLFSSS VMIIMKASYL DAGLAGILLS NAFSFTETAQ WIIKVFSSVE
1260 1270 1280 1290 1300
LLMSSVERIK EYTDIPSESN GYISPPANWP QTGDVELKNL SLRYSPHSSK
1310 1320 1330 1340 1350
ALDNVSFKVK AGTKVGIVGR TGAGKSSIIA AIYRLSDWEN GTITIDNKDI
1360 1370 1380 1390 1400
KHIPLERLRN SISCIPQDPT LFDGTVRSNL DPFDRYSDVQ IYGVLSKVGL
1410 1420 1430 1440 1450
IEECDELCLI FEQEQPNFSS HKLRNRFIDL NTVVKSGGSN LSQGQRQLLC
1460 1470 1480 1490 1500
LARSMLGARN IMLIDEATAS IDYISDAKIQ KTIRETMKNT TILTIAHRLR
1510 1520 1530 1540 1550
SVIDYDKILV MEMGRVKEYD HPYTLISDRN TIFYRLCRQS GEFENLFELA
KVSFDNKR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY230264 Genomic DNA Translation: AAO73540.1 AY230265 Genomic DNA Translation: AAO73541.1 AY230266 Genomic DNA Translation: AAO73542.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY230264 Genomic DNA Translation: AAO73540.1 AY230265 Genomic DNA Translation: AAO73541.1 AY230266 Genomic DNA Translation: AAO73542.1 |
3D structure databases
SMRi | P0CE70 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | P0CE70, 3 interactors |
MINTi | P0CE70 |
Organism-specific databases
VEuPathDBi | FungiDB:YKR103W FungiDB:YKR104W |
Family and domain databases
Gene3Di | 1.20.1560.10, 2 hits 3.40.50.300, 2 hits |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR011527, ABC1_TM_dom IPR036640, ABC1_TM_sf IPR003439, ABC_transporter-like_ATP-bd IPR017871, ABC_transporter-like_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00664, ABC_membrane, 2 hits PF00005, ABC_tran, 2 hits |
SMARTi | View protein in SMART SM00382, AAA, 2 hits |
SUPFAMi | SSF52540, SSF52540, 2 hits SSF90123, SSF90123, 2 hits |
PROSITEi | View protein in PROSITE PS50929, ABC_TM1F, 2 hits PS00211, ABC_TRANSPORTER_1, 2 hits PS50893, ABC_TRANSPORTER_2, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | NFT1_YEASX | |
Accessioni | P0CE70Primary (citable) accession number: P0CE70 Secondary accession number(s): P36028 Q6Q5L3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 23, 2010 |
Last sequence update: | March 23, 2010 | |
Last modified: | February 23, 2022 | |
This is version 63 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |