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Protein

Glucuronide carrier protein homolog

Gene

uidB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

The protein is inactive for transport, probably due to the presence of a Leu instead of a Pro at position 100.Curated

GO - Molecular functioni

  • transporter activity Source: EcoCyc

GO - Biological processi

Enzyme and pathway databases

BioCyciEcoCyc:UIDB-MONOMER
MetaCyc:UIDB-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glucuronide carrier protein homolog
Gene namesi
Name:uidB
Synonyms:gusB, uidP
Ordered Locus Names:b1616, JW1608
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11658 uidB

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 11CytoplasmicSequence analysisAdd BLAST11
Transmembranei12 – 34HelicalSequence analysisAdd BLAST23
Topological domaini35 – 37PeriplasmicSequence analysis3
Transmembranei38 – 60HelicalSequence analysisAdd BLAST23
Topological domaini61 – 79CytoplasmicSequence analysisAdd BLAST19
Transmembranei80 – 100HelicalSequence analysisAdd BLAST21
Topological domaini101 – 108PeriplasmicSequence analysis8
Transmembranei109 – 129HelicalSequence analysisAdd BLAST21
Topological domaini130 – 146CytoplasmicSequence analysisAdd BLAST17
Transmembranei147 – 167HelicalSequence analysisAdd BLAST21
Topological domaini168 – 180PeriplasmicSequence analysisAdd BLAST13
Transmembranei181 – 201HelicalSequence analysisAdd BLAST21
Topological domaini202 – 228CytoplasmicSequence analysisAdd BLAST27
Transmembranei229 – 249HelicalSequence analysisAdd BLAST21
Topological domaini250 – 263PeriplasmicSequence analysisAdd BLAST14
Transmembranei264 – 284HelicalSequence analysisAdd BLAST21
Topological domaini285 – 296CytoplasmicSequence analysisAdd BLAST12
Transmembranei297 – 316HelicalSequence analysisAdd BLAST20
Topological domaini317 – 320PeriplasmicSequence analysis4
Transmembranei321 – 343HelicalSequence analysisAdd BLAST23
Topological domaini344 – 372CytoplasmicSequence analysisAdd BLAST29
Transmembranei373 – 393HelicalSequence analysisAdd BLAST21
Topological domaini394 – 408PeriplasmicSequence analysisAdd BLAST15
Transmembranei409 – 429HelicalSequence analysisAdd BLAST21
Topological domaini430 – 457CytoplasmicSequence analysisAdd BLAST28

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001707621 – 457Glucuronide carrier protein homologAdd BLAST457

Proteomic databases

PaxDbiP0CE44
PRIDEiP0CE44

Interactioni

Protein-protein interaction databases

BioGridi4260252, 11 interactors
STRINGi316385.ECDH10B_1749

Structurei

3D structure databases

ProteinModelPortaliP0CE44
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CT4 Bacteria
COG2211 LUCA
InParanoidiP0CE44
KOiK16139

Family and domain databases

InterProiView protein in InterPro
IPR036259 MFS_trans_sf
IPR001927 Na/Gal_symport
IPR018043 Na/Gal_symport_CS
SUPFAMiSSF103473 SSF103473, 1 hit
TIGRFAMsiTIGR00792 gph, 1 hit
PROSITEiView protein in PROSITE
PS00872 NA_GALACTOSIDE_SYMP, 1 hit

Sequencei

Sequence statusi: Complete.

P0CE44-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQQLSWRTI VGYSLGDVAN NFAFAMGALF LLSYYTDVAG VGAAAAGTML
60 70 80 90 100
LLVRVFDAFA DVFAGRVVDS VNTRWGKFRP FLLFGTAPLM IFSVLVFWVL
110 120 130 140 150
TDWSHGSKVV YAYLTYMGLG LCYSLVNIPY GSLATAMTQQ PQSRARLGAA
160 170 180 190 200
RGIAASLTFV CLAFLIGPSI KNSSPEEMVS VYHFWTIVLA IAGMVLYFIC
210 220 230 240 250
FKSTRENVVR IVAQPSLNIS LQTLKRNRPL FMLCIGALCV LISTFAVSAS
260 270 280 290 300
SLFYVRYVLN DTGLFTVLVL VQNLVGTVAS APLVPGMVAR IGKKNTFLIG
310 320 330 340 350
ALLGTCGYLL FFWVSVWSLP VALVALAIAS IGQGVTMTVM WALEADTVEY
360 370 380 390 400
GEYLTGVRIE GLTYSLFSFT RKCGQAIGGS IPAFILGLSG YIANQVQTPE
410 420 430 440 450
VIMGIRTSIA LVPCGFMLLA FVIIWFYPLT DKKFKEIVVE IDNRKKVQQQ

LISDITN
Length:457
Mass (Da):49,908
Last modified:March 23, 2010 - v1
Checksum:i3A42E978FDB53F04
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74688.1
AP009048 Genomic DNA Translation: BAA15367.1
PIRiB64918
RefSeqiNP_416133.1, NC_000913.3
WP_001075849.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74688; AAC74688; b1616
BAA15367; BAA15367; BAA15367
GeneIDi947484
KEGGiecj:JW1608
eco:b1616
PATRICifig|1411691.4.peg.645

Similar proteinsi

Entry informationi

Entry nameiUIDB_ECOLI
AccessioniPrimary (citable) accession number: P0CE44
Secondary accession number(s): P30868, P77457
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 23, 2010
Last sequence update: March 23, 2010
Last modified: February 28, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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