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Entry version 85 (07 Apr 2021)
Sequence version 1 (03 Mar 2009)
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Protein

Camelliol C synthase

Gene

CAMS1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Converts oxidosqualene to camelliol C. Minor production of achilleol and beta-amyrin.

1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei486Proton donorBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIsomerase

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ARA:AT1G78955-MONOMER
MetaCyc:AT1G78955-MONOMER

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
5.4.99.38, 399

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Camelliol C synthase (EC:5.4.99.38)
Alternative name(s):
Lupeol synthase 3
Short name:
AtLUP3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CAMS1
Synonyms:LUP3
Ordered Locus Names:At1g78955
ORF Names:YUP8H12R.44
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G78955

The Arabidopsis Information Resource

More...
TAIRi
locus:504956092, AT1G78955

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003661331 – 769Camelliol C synthaseAdd BLAST769

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P0C8Y0

PRoteomics IDEntifications database

More...
PRIDEi
P0C8Y0

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
238532

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P0C8Y0, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT1G78955.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P0C8Y0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati149 – 190PFTB 1Add BLAST42
Repeati641 – 682PFTB 2Add BLAST42

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the terpene cyclase/mutase family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0497, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_009074_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P0C8Y0

Database of Orthologous Groups

More...
OrthoDBi
365003at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P0C8Y0

Family and domain databases

Conserved Domains Database

More...
CDDi
cd02892, SQCY_1, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032696, SQ_cyclase_C
IPR032697, SQ_cyclase_N
IPR018333, Squalene_cyclase
IPR008930, Terpenoid_cyclase/PrenylTrfase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13243, SQHop_cyclase_C, 1 hit
PF13249, SQHop_cyclase_N, 1 hit

Structure-Function Linkage Database

More...
SFLDi
SFLDG01016, Prenyltransferase_Like_2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48239, SSF48239, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01787, squalene_cyclas, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

P0C8Y0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWKLKIANGN KEEPYLFSTN NFLGRQTWEF DPDAGTVEEL AAVEEARRKF
60 70 80 90 100
YDDRFRVKAS SDLIWRMQFL KEKKFEQVIP PAKVEDANNI TSEIATNALR
110 120 130 140 150
KGVNFLSALQ ASDGHWPAEN AGPLFFLPPL VFCLYVTGHL HEIFTQDHRR
160 170 180 190 200
EVLRYIYCHQ NEDGGWGLHI EGNSTMFCTT LNYICMRILG EGPNGGPGNA
210 220 230 240 250
CKRARDWILD HGGATYIPSW GKTWLSILGV FDWSGSNPMP PEFWILPSFL
260 270 280 290 300
PIHPAKMWCY CRLVYMPMSY LYGKRFVGPI SPLILQLREE IYLQPYAKIN
310 320 330 340 350
WNRARHLCAK EDAYCPHPQI QDVIWNCLYI FTEPFLACWP FNKLLREKAL
360 370 380 390 400
GVAMKHIHYE DENSRYITIG CVEKALCMLA CWVEDPNGIH FKKHLLRISD
410 420 430 440 450
YLWIAEDGMK MQSFGSQLWD SGFALQALVA SNLVNEIPDV LRRGYDFLKN
460 470 480 490 500
SQVRENPSGD FTNMYRHISK GSWTFSDRDH GWQASDCTAE SFKCCLLLSM
510 520 530 540 550
IPPDIVGPKM DPEQLYEAVT ILLSLQSKNG GVTAWEPARG QEWLELLNPT
560 570 580 590 600
EVFADIVVEH EYNECTSSAI QALILFKQLY PNHRTEEINT SIKKAVQYIE
610 620 630 640 650
SIQMLDGSWY GSWGVCFTYS TWFGLGGLAA AGKTYNNCLA MRKGVHFLLT
660 670 680 690 700
TQKDNGGWGE SYLSCPKKRY IPSEGERSNL VQTSWAMMGL LHAGQAERDP
710 720 730 740 750
SPLHRAAKLL INSQLENGDF PQQEITGAFM KNCLLHYAAY RNIFPVWALA
760
EYRRRVPLPY EKPSTERRS
Length:769
Mass (Da):88,156
Last modified:March 3, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i30B7372DD5703C60
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8ARV5A0A1P8ARV5_ARATH
Terpene cyclase/mutase family membe...
CAMS1 camelliol C synthase 1, At1g78955
663Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8ARV6A0A1P8ARV6_ARATH
Terpene cyclase/mutase family membe...
CAMS1 camelliol C synthase 1, At1g78955
609Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A178WKN4A0A178WKN4_ARATH
Terpene cyclase/mutase family membe...
CAMS1 camelliol C synthase 1, At1g78955
704Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8ARW8A0A1P8ARW8_ARATH
Camelliol C synthase 1
CAMS1 camelliol C synthase 1, At1g78955
594Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC002986 Genomic DNA Translation: AAC17080.1
CP002684 Genomic DNA Translation: AEE36184.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T01060

NCBI Reference Sequences

More...
RefSeqi
NP_683508.1, NM_148667.2

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G78955.1; AT1G78955.1; AT1G78955

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
844235

Gramene; a comparative resource for plants

More...
Gramenei
AT1G78955.1; AT1G78955.1; AT1G78955

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G78955

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002986 Genomic DNA Translation: AAC17080.1
CP002684 Genomic DNA Translation: AEE36184.1
PIRiT01060
RefSeqiNP_683508.1, NM_148667.2

3D structure databases

SMRiP0C8Y0
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT1G78955.1

Proteomic databases

PaxDbiP0C8Y0
PRIDEiP0C8Y0
ProteomicsDBi238532

Genome annotation databases

EnsemblPlantsiAT1G78955.1; AT1G78955.1; AT1G78955
GeneIDi844235
GrameneiAT1G78955.1; AT1G78955.1; AT1G78955
KEGGiath:AT1G78955

Organism-specific databases

AraportiAT1G78955
TAIRilocus:504956092, AT1G78955

Phylogenomic databases

eggNOGiKOG0497, Eukaryota
HOGENOMiCLU_009074_2_0_1
InParanoidiP0C8Y0
OrthoDBi365003at2759
PhylomeDBiP0C8Y0

Enzyme and pathway databases

BioCyciARA:AT1G78955-MONOMER
MetaCyc:AT1G78955-MONOMER
BRENDAi5.4.99.38, 399

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P0C8Y0

Gene expression databases

ExpressionAtlasiP0C8Y0, baseline and differential

Family and domain databases

CDDicd02892, SQCY_1, 1 hit
InterProiView protein in InterPro
IPR032696, SQ_cyclase_C
IPR032697, SQ_cyclase_N
IPR018333, Squalene_cyclase
IPR008930, Terpenoid_cyclase/PrenylTrfase
PfamiView protein in Pfam
PF13243, SQHop_cyclase_C, 1 hit
PF13249, SQHop_cyclase_N, 1 hit
SFLDiSFLDG01016, Prenyltransferase_Like_2, 1 hit
SUPFAMiSSF48239, SSF48239, 2 hits
TIGRFAMsiTIGR01787, squalene_cyclas, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLUP3_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P0C8Y0
Secondary accession number(s): O64553
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 7, 2021
This is version 85 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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