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Protein

Coiled-coil domain-containing protein 172

Gene

CCDC172

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Coiled-coil domain-containing protein 172
Gene namesi
Name:CCDC172
Synonyms:C10orf96
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000182645.5
HGNCiHGNC:30524 CCDC172
neXtProtiNX_P0C7W6

Subcellular locationi

Keywords - Cellular componenti

Cell projection, Cytoplasm

Pathology & Biotechi

Organism-specific databases

DisGeNETi374355
OpenTargetsiENSG00000182645
PharmGKBiPA134867240

Polymorphism and mutation databases

BioMutaiCCDC172
DMDMi206557852

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003445131 – 258Coiled-coil domain-containing protein 172Add BLAST258

Proteomic databases

MaxQBiP0C7W6
PaxDbiP0C7W6
PeptideAtlasiP0C7W6
PRIDEiP0C7W6
ProteomicsDBi52381

PTM databases

iPTMnetiP0C7W6
PhosphoSitePlusiP0C7W6

Expressioni

Gene expression databases

BgeeiENSG00000182645
CleanExiHS_C10orf96
GenevisibleiP0C7W6 HS

Interactioni

Subunit structurei

May interact with TEKT2.By similarity

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi131893, 17 interactors
IntActiP0C7W6, 26 interactors
MINTiP0C7W6

Structurei

3D structure databases

ProteinModelPortaliP0C7W6
SMRiP0C7W6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili13 – 90Sequence analysisAdd BLAST78
Coiled coili123 – 191Sequence analysisAdd BLAST69
Coiled coili226 – 256Sequence analysisAdd BLAST31

Sequence similaritiesi

Belongs to the CCDC172 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IWRG Eukaryota
ENOG4112A44 LUCA
GeneTreeiENSGT00390000005203
HOGENOMiHOG000111699
HOVERGENiHBG106901
InParanoidiP0C7W6
OMAiHIIFSEH
OrthoDBiEOG091G0OD3
PhylomeDBiP0C7W6
TreeFamiTF333231

Family and domain databases

InterProiView protein in InterPro
IPR029618 CCDC172
PANTHERiPTHR22419 PTHR22419, 1 hit

Sequencei

Sequence statusi: Complete.

P0C7W6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLESLFQHI IFTEHQAEES RRLMREVRSE ITRCREKIKK ATEELNEEKI
60 70 80 90 100
KLESKVQQFF EKSFFLQLLK AHENALEKQY SEITNHRNML LQTFEAIKKQ
110 120 130 140 150
MIEEEDKFIK EITDFNNDYE ITKKRELLMK ENVKIEISDL ENQANMLKSE
160 170 180 190 200
MKSMEHDSSQ LNELQKQKSE LIQELFTLQR KLKVFEDEEN ESICTTKYLE
210 220 230 240 250
AEKIKISEKP QNDTECLRLK KELELYKEDD MESVYEALQT EIEFLELTLA

QKDLQESK
Length:258
Mass (Da):31,035
Last modified:July 22, 2008 - v1
Checksum:i9CFC9C42B13486B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011328 Genomic DNA No translation available.
BC044830 mRNA Translation: AAH44830.1
CCDSiCCDS31291.1
RefSeqiNP_940917.1, NM_198515.2
XP_016871695.1, XM_017016206.1
UniGeneiHs.233407

Genome annotation databases

EnsembliENST00000333254; ENSP00000329860; ENSG00000182645
GeneIDi374355
KEGGihsa:374355
UCSCiuc001lck.3 human

Similar proteinsi

Entry informationi

Entry nameiCC172_HUMAN
AccessioniPrimary (citable) accession number: P0C7W6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: July 22, 2008
Last modified: June 20, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

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