The new UniProt website is here!
Take me to UniProt BETA
UniProtKB - P0C7W0 (PRR29_HUMAN)
Protein
Proline-rich protein 29
Gene
PRR29
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Proline-rich protein 29 |
Gene namesi | Name:PRR29 Synonyms:C17orf72 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:25673, PRR29 |
neXtProti | NX_P0C7W0 |
VEuPathDBi | HostDB:ENSG00000224383 |
Pathology & Biotechi
Organism-specific databases
OpenTargetsi | ENSG00000224383 |
PharmGKBi | PA142672220 |
Miscellaneous databases
Pharosi | P0C7W0, Tdark |
Genetic variation databases
BioMutai | PRR29 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000344468 | 1 – 189 | Proline-rich protein 29Add BLAST | 189 |
Proteomic databases
MassIVEi | P0C7W0 |
PaxDbi | P0C7W0 |
PeptideAtlasi | P0C7W0 |
PRIDEi | P0C7W0 |
ProteomicsDBi | 20341 52380 [P0C7W0-1] |
Expressioni
Gene expression databases
Bgeei | ENSG00000224383, Expressed in right uterine tube and 179 other tissues |
ExpressionAtlasi | P0C7W0, baseline and differential |
Genevisiblei | P0C7W0, HS |
Organism-specific databases
HPAi | ENSG00000224383, Tissue enriched (fallopian) |
Interactioni
Protein-protein interaction databases
STRINGi | 9606.ENSP00000396936 |
Miscellaneous databases
RNActi | P0C7W0, protein |
Structurei
3D structure databases
AlphaFoldDBi | P0C7W0 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 152 – 189 | DisorderedSequence analysisAdd BLAST | 38 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 157 – 171 | Pro residuesSequence analysisAdd BLAST | 15 |
Phylogenomic databases
eggNOGi | ENOG502S6FU, Eukaryota |
GeneTreei | ENSGT00390000002000 |
HOGENOMi | CLU_2333053_0_0_1 |
InParanoidi | P0C7W0 |
OMAi | HYLPCPM |
OrthoDBi | 1322603at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR027904, DUF4587 IPR038915, PRR29-like |
PANTHERi | PTHR28604, PTHR28604, 1 hit |
Pfami | View protein in Pfam PF15248, DUF4587, 1 hit |
s (4+)i Sequence
Sequence statusi: Complete.
This entry describes 4 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 4 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: P0C7W0-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MASGAGGSWG RSPPQSAVPT PWVTFLQPLS WAVPPAPPQP GRVKEDLLEL
60 70 80 90 100
MMLQNAQMHQ LLLSRLVAGA LQPRPASPCP QVYLEVPQEE PEEEEEEMDV
110 120 130 140 150
REKGPLVFHH HYLPYLMPSP GALLPWPAPF FPTPACQPYL QDVPRIQHCP
160 170 180
ASREREVRAV PPPPPPSATG TVGADVPPAS DYYDAESLL
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketJ3QR92 | J3QR92_HUMAN | Proline-rich protein 29 | PRR29 | 138 | Annotation score: | ||
J3KRF4 | J3KRF4_HUMAN | Proline-rich protein 29 | PRR29 | 37 | Annotation score: | ||
J3KRR4 | J3KRR4_HUMAN | Proline-rich protein 29 | PRR29 | 156 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 145 | R → S in BAG51052 (PubMed:14702039).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_069055 | 24 | T → S1 PublicationCorresponds to variant dbSNP:rs62070903Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_046997 | 22 – 28 | Missing in isoform 4. 1 Publication | 7 | |
Alternative sequenceiVSP_045344 | 82 – 98 | VYLEV…EEEEM → ESCAPTPTPQCHRDCGC in isoform 3. 1 PublicationAdd BLAST | 17 | |
Alternative sequenceiVSP_045345 | 99 – 189 | Missing in isoform 3. 1 PublicationAdd BLAST | 91 | |
Alternative sequenceiVSP_045346 | 157 – 189 | VRAVP…AESLL → TTMMPRASYEDRPRPWELHQ LPALDTAPEPPPAPLLSTPR CPWLAVLLTPSTSARPSSPG EISPCPTPMSSWTGRICAVV in isoform 2. 1 PublicationAdd BLAST | 33 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK021786 mRNA Translation: BAG51052.1 AK302960 mRNA Translation: BAG64111.1 AK304254 mRNA Translation: BAG65120.1 DB037384 mRNA No translation available. AC005803 Genomic DNA No translation available. |
CCDSi | CCDS54157.1 [P0C7W0-2] CCDS54158.1 [P0C7W0-1] CCDS54159.1 [P0C7W0-3] CCDS58586.1 [P0C7W0-4] |
RefSeqi | NP_001157729.1, NM_001164257.1 [P0C7W0-1] NP_001177958.1, NM_001191029.1 [P0C7W0-2] NP_001177959.1, NM_001191030.1 [P0C7W0-4] NP_001177960.1, NM_001191031.1 [P0C7W0-3] |
Genome annotation databases
Ensembli | ENST00000412177.6; ENSP00000400986.1; ENSG00000224383.8 ENST00000425164.7; ENSP00000396936.3; ENSG00000224383.8 [P0C7W0-2] ENST00000577953.5; ENSP00000463279.1; ENSG00000224383.8 [P0C7W0-3] ENST00000579184.5; ENSP00000462097.1; ENSG00000224383.8 [P0C7W0-4] |
GeneIDi | 92340 |
KEGGi | hsa:92340 |
MANE-Selecti | ENST00000412177.6; ENSP00000400986.1; NM_001164257.2; NP_001157729.1 |
UCSCi | uc002jdt.5, human [P0C7W0-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK021786 mRNA Translation: BAG51052.1 AK302960 mRNA Translation: BAG64111.1 AK304254 mRNA Translation: BAG65120.1 DB037384 mRNA No translation available. AC005803 Genomic DNA No translation available. |
CCDSi | CCDS54157.1 [P0C7W0-2] CCDS54158.1 [P0C7W0-1] CCDS54159.1 [P0C7W0-3] CCDS58586.1 [P0C7W0-4] |
RefSeqi | NP_001157729.1, NM_001164257.1 [P0C7W0-1] NP_001177958.1, NM_001191029.1 [P0C7W0-2] NP_001177959.1, NM_001191030.1 [P0C7W0-4] NP_001177960.1, NM_001191031.1 [P0C7W0-3] |
3D structure databases
AlphaFoldDBi | P0C7W0 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9606.ENSP00000396936 |
Genetic variation databases
BioMutai | PRR29 |
Proteomic databases
MassIVEi | P0C7W0 |
PaxDbi | P0C7W0 |
PeptideAtlasi | P0C7W0 |
PRIDEi | P0C7W0 |
ProteomicsDBi | 20341 52380 [P0C7W0-1] |
Protocols and materials databases
Antibodypediai | 52676, 1 antibodies from 1 providers |
DNASUi | 92340 |
Genome annotation databases
Ensembli | ENST00000412177.6; ENSP00000400986.1; ENSG00000224383.8 ENST00000425164.7; ENSP00000396936.3; ENSG00000224383.8 [P0C7W0-2] ENST00000577953.5; ENSP00000463279.1; ENSG00000224383.8 [P0C7W0-3] ENST00000579184.5; ENSP00000462097.1; ENSG00000224383.8 [P0C7W0-4] |
GeneIDi | 92340 |
KEGGi | hsa:92340 |
MANE-Selecti | ENST00000412177.6; ENSP00000400986.1; NM_001164257.2; NP_001157729.1 |
UCSCi | uc002jdt.5, human [P0C7W0-1] |
Organism-specific databases
CTDi | 92340 |
GeneCardsi | PRR29 |
HGNCi | HGNC:25673, PRR29 |
HPAi | ENSG00000224383, Tissue enriched (fallopian) |
neXtProti | NX_P0C7W0 |
OpenTargetsi | ENSG00000224383 |
PharmGKBi | PA142672220 |
VEuPathDBi | HostDB:ENSG00000224383 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502S6FU, Eukaryota |
GeneTreei | ENSGT00390000002000 |
HOGENOMi | CLU_2333053_0_0_1 |
InParanoidi | P0C7W0 |
OMAi | HYLPCPM |
OrthoDBi | 1322603at2759 |
Enzyme and pathway databases
PathwayCommonsi | P0C7W0 |
Miscellaneous databases
BioGRID-ORCSi | 92340, 5 hits in 1066 CRISPR screens |
ChiTaRSi | PRR29, human |
GenomeRNAii | 92340 |
Pharosi | P0C7W0, Tdark |
PROi | PR:P0C7W0 |
RNActi | P0C7W0, protein |
Gene expression databases
Bgeei | ENSG00000224383, Expressed in right uterine tube and 179 other tissues |
ExpressionAtlasi | P0C7W0, baseline and differential |
Genevisiblei | P0C7W0, HS |
Family and domain databases
InterProi | View protein in InterPro IPR027904, DUF4587 IPR038915, PRR29-like |
PANTHERi | PTHR28604, PTHR28604, 1 hit |
Pfami | View protein in Pfam PF15248, DUF4587, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | PRR29_HUMAN | |
Accessioni | P0C7W0Primary (citable) accession number: P0C7W0 Secondary accession number(s): B3KMP0 J3QKX4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 22, 2008 |
Last sequence update: | February 6, 2013 | |
Last modified: | May 25, 2022 | |
This is version 81 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 17
Human chromosome 17: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports