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UniProtKB - P0C794 (MATRX_BDV1)
Protein
Matrix protein
Gene
M
Organism
Borna disease virus 1 (BoDV-1)
Status
Functioni
Plays a crucial role in virion assembly and budding.
CuratedSites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 117 | GMP; via carbonyl oxygenCombined sources | 1 |
GO - Molecular functioni
- identical protein binding Source: IntAct
- structural constituent of virion Source: UniProtKB-KW
Names & Taxonomyi
Subcellular locationi
- Virion Curated
- Host cytoplasm By similarity
- Host cell membrane ; Peripheral membrane protein 1 Publication Note: During viral budding, associates with the inner side of the plasma membrane of infected cells (PubMed:11711600). Found in nuclear punctate structures that have been proposed to be the sites of viral replication and transcription, also termed viral speckles of transcripts (vSPOTs) (By similarity).By similarity1 Publication
Keywords - Cellular componenti
Host cell membrane, Host cytoplasm, Host membrane, Membrane, Viral matrix protein, VirionPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000079206 | 1 – 142 | Matrix proteinAdd BLAST | 142 |
Post-translational modificationi
Not glycosylated.1 Publication
Interactioni
Subunit structurei
Binary interactionsi
P0C794
With | #Exp. | IntAct |
---|---|---|
itself | 2 | EBI-15760176,EBI-15760176 |
GO - Molecular functioni
- identical protein binding Source: IntAct
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P0C794 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P0C794 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 64 – 66 | GMP bindingCombined sources | 3 |
Family and domain databases
Gene3Di | 2.70.20.40, 1 hit |
InterProi | View protein in InterPro IPR032414, BDV_M IPR038520, BDV_M_sf |
Pfami | View protein in Pfam PF16520, BDV_M, 1 hit |
s (3)i Sequence
Sequence statusi: Complete.
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketIsoform Matrix protein (identifier: P0C794-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MNSKHSYVEL KDKVIVPGWP TLMLEIDFVG GTSRNQFLNI PFLSVKEPLQ
60 70 80 90 100
LPREKKLTDY FTIDVEPAGH SLVNIYFQID DFLLLTLNSL SVYKDPIRKY
110 120 130 140
MFLRLNKEQS KHAINAAFNV FSYRLRNIGV GPLGPDIRSS GP
Isoform Envelope glycoprotein p57 precursor (identifier: Q8BB27-1) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry Q8BB27.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Isoform Large structural protein (identifier: Q8JMN0-1) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry Q8JMN0.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 12 | D → G in AAA20665 (Ref. 2) Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural varianti | 108 | E → D in strain: Isolate H1 and Isolate H2. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L76228 Genomic RNA Translation: AAA91188.1 L76230 Genomic RNA Translation: AAA91189.1 L27077 Genomic RNA Translation: AAA20665.2 U94865 Genomic RNA Translation: AAB53714.1 U94869 Genomic RNA Translation: AAB53718.1 U94873 Genomic RNA Translation: AAB53722.1 U94877 Genomic RNA Translation: AAB53726.1 U94881 Genomic RNA Translation: AAB53730.1 |
RefSeqi | NP_042022.1, NC_001607.1 |
Genome annotation databases
GeneIDi | 26799165 |
KEGGi | vg:26799165 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L76228 Genomic RNA Translation: AAA91188.1 L76230 Genomic RNA Translation: AAA91189.1 L27077 Genomic RNA Translation: AAA20665.2 U94865 Genomic RNA Translation: AAB53714.1 U94869 Genomic RNA Translation: AAB53718.1 U94873 Genomic RNA Translation: AAB53722.1 U94877 Genomic RNA Translation: AAB53726.1 U94881 Genomic RNA Translation: AAB53730.1 |
RefSeqi | NP_042022.1, NC_001607.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3F1J | X-ray | 2.65 | A | 1-142 | [»] | |
4HI5 | X-ray | 3.60 | A | 1-142 | [»] | |
4HI6 | X-ray | 2.20 | A/B/C/D | 1-142 | [»] | |
4HIT | X-ray | 2.40 | A/B/C/D | 1-142 | [»] | |
4HIU | X-ray | 3.30 | A | 1-142 | [»] | |
4HIW | X-ray | 2.90 | A | 1-142 | [»] | |
4HIY | X-ray | 3.31 | A | 1-142 | [»] | |
SMRi | P0C794 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Genome annotation databases
GeneIDi | 26799165 |
KEGGi | vg:26799165 |
Miscellaneous databases
EvolutionaryTracei | P0C794 |
Family and domain databases
Gene3Di | 2.70.20.40, 1 hit |
InterProi | View protein in InterPro IPR032414, BDV_M IPR038520, BDV_M_sf |
Pfami | View protein in Pfam PF16520, BDV_M, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | MATRX_BDV1 | |
Accessioni | P0C794Primary (citable) accession number: P0C794 Secondary accession number(s): P52637 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 8, 2011 |
Last sequence update: | March 8, 2011 | |
Last modified: | September 29, 2021 | |
This is version 46 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Viral Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencingDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references