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Protein

Solute carrier family 2, facilitated glucose transporter member 7

Gene

Slc2a7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei332MonosaccharideBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processSugar transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 2, facilitated glucose transporter member 7
Alternative name(s):
Glucose transporter type 7
Short name:
GLUT-7
Gene namesi
Name:Slc2a7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:3650865 Slc2a7

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 21CytoplasmicSequence analysisAdd BLAST21
Transmembranei22 – 42HelicalSequence analysisAdd BLAST21
Topological domaini43 – 78ExtracellularSequence analysisAdd BLAST36
Transmembranei79 – 99HelicalSequence analysisAdd BLAST21
Topological domaini100 – 107CytoplasmicSequence analysis8
Transmembranei108 – 128HelicalSequence analysisAdd BLAST21
Topological domaini129 – 138ExtracellularSequence analysis10
Transmembranei139 – 159HelicalSequence analysisAdd BLAST21
Topological domaini160 – 172CytoplasmicSequence analysisAdd BLAST13
Transmembranei173 – 193HelicalSequence analysisAdd BLAST21
Topological domaini194 – 198ExtracellularSequence analysis5
Transmembranei199 – 219HelicalSequence analysisAdd BLAST21
Topological domaini220 – 282CytoplasmicSequence analysisAdd BLAST63
Transmembranei283 – 303HelicalSequence analysisAdd BLAST21
Topological domaini304 – 322ExtracellularSequence analysisAdd BLAST19
Transmembranei323 – 343HelicalSequence analysisAdd BLAST21
Topological domaini344 – 351CytoplasmicSequence analysis8
Transmembranei352 – 372HelicalSequence analysisAdd BLAST21
Topological domaini373 – 380ExtracellularSequence analysis8
Transmembranei381 – 401HelicalSequence analysisAdd BLAST21
Topological domaini402 – 416CytoplasmicSequence analysisAdd BLAST15
Transmembranei417 – 437HelicalSequence analysisAdd BLAST21
Topological domaini438 – 446ExtracellularSequence analysis9
Transmembranei447 – 467HelicalSequence analysisAdd BLAST21
Topological domaini468 – 513CytoplasmicSequence analysisAdd BLAST46

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003172721 – 513Solute carrier family 2, facilitated glucose transporter member 7Add BLAST513

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi57N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiP0C6A1
PRIDEiP0C6A1

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059106

Structurei

3D structure databases

ProteinModelPortaliP0C6A1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni295 – 301Monosaccharide bindingBy similarity7

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0569 Eukaryota
COG0477 LUCA
HOVERGENiHBG014816
InParanoidiP0C6A1

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR003663 Sugar/inositol_transpt
IPR005829 Sugar_transporter_CS
PfamiView protein in Pfam
PF00083 Sugar_tr, 1 hit
PRINTSiPR00171 SUGRTRNSPORT
SUPFAMiSSF103473 SSF103473, 1 hit
TIGRFAMsiTIGR00879 SP, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
PS00216 SUGAR_TRANSPORT_1, 1 hit
PS00217 SUGAR_TRANSPORT_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P0C6A1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEDKEIGTPL PLPHSEARLQ PTLVLTTLSA AFGSVFQYGY NIAVINTPHK
60 70 80 90 100
VFKSFYNDTH FERHGTFMDE STLLLLWSCT VSMFPLGGLL GSLVVGLMVN
110 120 130 140 150
KWGRKGTLLI NNVFAITSAV LMGVSKVARA FELIILSRVL VGICAGIAYS
160 170 180 190 200
TLPMYLGELA PQNLRGALGT MTEVFVIIGV LLAQIFSLQA ILGNATGWPI
210 220 230 240 250
LLALTGVPAV IQLLSLPFFP ESPRYTLIEK GDEETARQAL RRLRGQNYNV
260 270 280 290 300
EAEMEEMRTE ERTEQAEGRL SVLNLFTFRP LRWQLISIVV LMAGQQLSGI
310 320 330 340 350
NAVNYYADVI YTSAGVDPTQ SQYVTLGSGV INLVMTLVSA VIIERLGRRI
360 370 380 390 400
LLLSGYAICC SACLVLTVAL LLQSTAPELS YLSIVCVFSY IVGHSIGPSP
410 420 430 440 450
VPSVVRTEIV LQSSRTAAFT VDGAVHWLTN FIVGLTFPSI QVAIGAYSFL
460 470 480 490 500
VFAGVCILTA AYIYVVIPET KGRTFVEINC AFAKRNGVEF PEEKEVATAK
510
PHTPSLPTKE TAF
Length:513
Mass (Da):55,886
Last modified:February 5, 2008 - v1
Checksum:iC4FFBFE9EE8061B9
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B1ARZ3B1ARZ3_MOUSE
Solute carrier family 2, facilitate...
Slc2a7
525Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL606971 Genomic DNA No translation available.
UniGeneiMm.359648

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL606971 Genomic DNA No translation available.
UniGeneiMm.359648

3D structure databases

ProteinModelPortaliP0C6A1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059106

Proteomic databases

PaxDbiP0C6A1
PRIDEiP0C6A1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:3650865 Slc2a7

Phylogenomic databases

eggNOGiKOG0569 Eukaryota
COG0477 LUCA
HOVERGENiHBG014816
InParanoidiP0C6A1

Miscellaneous databases

PROiPR:P0C6A1
SOURCEiSearch...

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR003663 Sugar/inositol_transpt
IPR005829 Sugar_transporter_CS
PfamiView protein in Pfam
PF00083 Sugar_tr, 1 hit
PRINTSiPR00171 SUGRTRNSPORT
SUPFAMiSSF103473 SSF103473, 1 hit
TIGRFAMsiTIGR00879 SP, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
PS00216 SUGAR_TRANSPORT_1, 1 hit
PS00217 SUGAR_TRANSPORT_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiGTR7_MOUSE
AccessioniPrimary (citable) accession number: P0C6A1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 5, 2008
Last modified: January 31, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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