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Protein

Actin-2

Gene

ACT2

Organism
Oryza sativa subsp. indica (Rice)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.

Miscellaneous

There are at least eight actin genes in rice.

GO - Molecular functioni

Keywordsi

LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-OSA-2029482 Regulation of actin dynamics for phagocytic cup formation
R-OSA-5663213 RHO GTPases Activate WASPs and WAVEs

Names & Taxonomyi

Protein namesi
Recommended name:
Actin-2
Gene namesi
Name:ACT2
Synonyms:AC2, RAC2
OrganismiOryza sativa subsp. indica (Rice)
Taxonomic identifieri39946 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002914551 – 377Actin-2Add BLAST377

Proteomic databases

PRIDEiP0C539

Expressioni

Gene expression databases

ExpressionAtlasiP0C539 differential

Structurei

3D structure databases

ProteinModelPortaliP0C539
SMRiP0C539
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the actin family.Curated

Phylogenomic databases

eggNOGiKOG0676 Eukaryota
COG5277 LUCA
HOGENOMiHOG000233339

Family and domain databases

InterProiView protein in InterPro
IPR004000 Actin
IPR020902 Actin/actin-like_CS
IPR004001 Actin_CS
PANTHERiPTHR11937 PTHR11937, 1 hit
PfamiView protein in Pfam
PF00022 Actin, 1 hit
PRINTSiPR00190 ACTIN
SMARTiView protein in SMART
SM00268 ACTIN, 1 hit
PROSITEiView protein in PROSITE
PS00406 ACTINS_1, 1 hit
PS00432 ACTINS_2, 1 hit
PS01132 ACTINS_ACT_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

P0C539-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADAEDIQPL VCDNGTGMVK AGFAGDDAPR AVFPSIVGRP RHTGVMVGMG
60 70 80 90 100
QKDAYVGDEA QSKRGILTLK YPIEHGIVSN WDDMEKIWHH TFYNELRVAP
110 120 130 140 150
EEHPILLTEA PLNPKANREK MTQIMFETFS VPAMYVAIQA VLSLYASGRT
160 170 180 190 200
TGIVLDSGDG VSHTVPIYEG YALPHAILRL DLAGRDLTDS LMKILTERGY
210 220 230 240 250
SFTTSAEREI VRDIKEKLAY VALDYEQELE TAKSSSSVEK SYELPDGQVI
260 270 280 290 300
TIGAERFRCP EVMFQPSLIG MEAPGIHETT YNSIMKCDVD IRKDLYGNIV
310 320 330 340 350
LSGGSTMFPG IADRMSKEIT ALAPSSMKIK VVAPPERKYS VWIGGSILAS
360 370
LSTFQQMWIS RAEYEESGPA IVHRKCF
Length:377
Mass (Da):41,680
Last modified:June 12, 2007 - v1
Checksum:i9F54046D3CE99007
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15864 Genomic DNA Translation: CAA33873.1
PIRiS10021 ATRZ2

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15864 Genomic DNA Translation: CAA33873.1
PIRiS10021 ATRZ2

3D structure databases

ProteinModelPortaliP0C539
SMRiP0C539
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP0C539

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0676 Eukaryota
COG5277 LUCA
HOGENOMiHOG000233339

Enzyme and pathway databases

ReactomeiR-OSA-2029482 Regulation of actin dynamics for phagocytic cup formation
R-OSA-5663213 RHO GTPases Activate WASPs and WAVEs

Gene expression databases

ExpressionAtlasiP0C539 differential

Family and domain databases

InterProiView protein in InterPro
IPR004000 Actin
IPR020902 Actin/actin-like_CS
IPR004001 Actin_CS
PANTHERiPTHR11937 PTHR11937, 1 hit
PfamiView protein in Pfam
PF00022 Actin, 1 hit
PRINTSiPR00190 ACTIN
SMARTiView protein in SMART
SM00268 ACTIN, 1 hit
PROSITEiView protein in PROSITE
PS00406 ACTINS_1, 1 hit
PS00432 ACTINS_2, 1 hit
PS01132 ACTINS_ACT_LIKE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiACT2_ORYSI
AccessioniPrimary (citable) accession number: P0C539
Secondary accession number(s): P17298
, Q0IWG7, Q7XCZ1, Q94GX5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: June 12, 2007
Last modified: October 10, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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