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UniProtKB - P0C2M9 (FYUA_YEREN)

Entry version 67 (25 May 2022)
Sequence version 1 (03 Apr 2007)
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Protein

Pesticin receptor

Gene

fyuA

Organism
Yersinia enterocolitica
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Receptor for the bacteriocin pesticin and for the siderophore yersiniabactin.

Miscellaneous

Weakly expressed by yersiniae located in the liver and the intestinal lumen. Strongly expressed in yersiniae located in the peritoneal cavity. Moderately expressed in yersiniae located in the spleen. This probably reflects the availability of iron for yersiniae.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor
Biological processIon transport, Iron transport, Transport
LigandIron

Protein family/group databases

Transport Classification Database

More...TCDBi		1.B.14.8.7, the outer membrane receptor (omr) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Pesticin receptor
Alternative name(s):
IPR65
IRPC
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:fyuA
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiYersinia enterocolitica
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri630 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Yersiniaceae › Yersinia

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell outer membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 22Sequence analysisAdd BLAST22
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000003475623 – 673Pesticin receptorAdd BLAST651

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Induced in absence of iron.

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		P0C2M9

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P0C2M9

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi30 – 37TonB box8
Motifi657 – 673TonB C-terminal boxAdd BLAST17

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TonB-dependent receptor family.Curated

Keywords - Domaini

Signal, TonB box, Transmembrane, Transmembrane beta strand

Phylogenomic databases

Database of Orthologous Groups

More...OrthoDBi		514956at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.40.170.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR039426, BtuB-like
IPR012910, Plug_dom
IPR000531, TonB-dep_rcpt_b-brl
IPR036942, TonB_rcpt_b-brl_sf
IPR010105, TonB_sidphr_rcpt

The PANTHER Classification System

More...PANTHERi		PTHR30069, PTHR30069, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF07715, Plug, 1 hit
PF00593, TonB_dep_Rec, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01783, TonB-siderophor, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P0C2M9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKMTRLYPLA LGGLLLPAIA NAQTSQQDES TLEVTASKQS SRSASANNVS 
        60         70         80         90        100
STVVSAPELS DAGVTASDKL PRVLPGLNIE NSGNMLFSTI SLRGVSSAQD 
       110        120        130        140        150
FYNPAVTLYV DGVPQLSTNT IQALTDVQSV ELLRGPQGTL YGKSAQGGII 
       160        170        180        190        200
NIVTQQPDST PRGYIEGGVS SRDSYRSKFN LSGPIQDGLL YGSVTLLRQV 
       210        220        230        240        250
DDGDMINPAT GSDDLGGTRA SIGNVKLRLA PDDQPWEMGF AASRECTRAT 
       260        270        280        290        300
QDAYVGWNDI KGRKLSLSDG SPDPYMRRCT DSQTLSGKYT TDDWVFNLIS 
       310        320        330        340        350
AWQQQHYSRT FPSGSLIVNM PQRWNQDVQE LRAATLGDAR TVDMVFGLYR 
       360        370        380        390        400
QNTREKLNSA YNMPTMPYLS STGYTTAETL AAYSDLTWHL TDRFDIGGGV 
       410        420        430        440        450
RFSHDKSSTQ YHGSMLGNPF GDQGKSNDDQ VLGQLSAGYM LTDDWRVYTR 
       460        470        480        490        500
IAQGYKPSGY NIVPTAGLDA KPFVAEKSIN YELGTRYETA DVTLQAATFY 
       510        520        530        540        550
THTKDMQLYS GPVGMQTLSN AGKADATGVE LEAKWRFAPG WSWDINGNVI 
       560        570        580        590        600
RSEFTNDSEL YHGNRVPFVP RYGAGSSVNG VIDTRYGALM PRLAVNLVGP 
       610        620        630        640        650
HYFDGDNQLR QGTYATLDSS LGWQATERIN ISVHVDNLFD RRYRTYGYMN 
       660        670 
GSSAVAQVNM GRTVGINTRI DFF
Length:673
Mass (Da):73,682
Last modified:April 3, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1C20E0352FAD4DCC
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti362N → D in strain: YE737 and 1209-79. 1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
Z29675 Genomic DNA Translation: CAA82773.1
Z35485 Genomic DNA Translation: CAA84620.1
Z35487 Genomic DNA Translation: CAA84622.1
Z35496 Genomic DNA Translation: CAA84630.1

Protein sequence database of the Protein Information Resource

More...PIRi		S60142

NCBI Reference Sequences

More...RefSeqi		WP_005168662.1, NZ_CQCV01000030.1
WP_011816644.1, NZ_NWMR01000021.1

Genome annotation databases

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		yew:CH47_1968

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z29675 Genomic DNA Translation: CAA82773.1
Z35485 Genomic DNA Translation: CAA84620.1
Z35487 Genomic DNA Translation: CAA84622.1
Z35496 Genomic DNA Translation: CAA84630.1
PIRiS60142
RefSeqiWP_005168662.1, NZ_CQCV01000030.1
WP_011816644.1, NZ_NWMR01000021.1

3D structure databases

AlphaFoldDBiP0C2M9
SMRiP0C2M9
ModBaseiSearch...

Protein family/group databases

TCDBi1.B.14.8.7, the outer membrane receptor (omr) family

Genome annotation databases

KEGGiyew:CH47_1968

Phylogenomic databases

OrthoDBi514956at2

Family and domain databases

Gene3Di2.40.170.20, 1 hit
InterProiView protein in InterPro
IPR039426, BtuB-like
IPR012910, Plug_dom
IPR000531, TonB-dep_rcpt_b-brl
IPR036942, TonB_rcpt_b-brl_sf
IPR010105, TonB_sidphr_rcpt
PANTHERiPTHR30069, PTHR30069, 1 hit
PfamiView protein in Pfam
PF07715, Plug, 1 hit
PF00593, TonB_dep_Rec, 1 hit
TIGRFAMsiTIGR01783, TonB-siderophor, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFYUA_YEREN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P0C2M9
Secondary accession number(s): P46360
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: April 3, 2007
Last modified: May 25, 2022
This is version 67 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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