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Protein

Protein FAM163B

Gene

FAM163B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM163B
Gene namesi
Name:FAM163B
Synonyms:C9orf166
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000196990.8
HGNCiHGNC:33277 FAM163B
neXtProtiNX_P0C2L3

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 26HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000196990
PharmGKBiPA162386945

Polymorphism and mutation databases

BioMutaiFAM163B
DMDMi134035404

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002802581 – 166Protein FAM163BAdd BLAST166

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei40PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP0C2L3
PeptideAtlasiP0C2L3
PRIDEiP0C2L3
ProteomicsDBi52303

PTM databases

iPTMnetiP0C2L3
PhosphoSitePlusiP0C2L3

Expressioni

Gene expression databases

BgeeiENSG00000196990 Expressed in 68 organ(s), highest expression level in anterior cingulate cortex
CleanExiHS_FAM163B

Organism-specific databases

HPAiHPA067336

Interactioni

Protein-protein interaction databases

IntActiP0C2L3, 2 interactors
MINTiP0C2L3
STRINGi9606.ENSP00000349336

Structurei

3D structure databases

ProteinModelPortaliP0C2L3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM163 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IWU6 Eukaryota
ENOG4111P95 LUCA
GeneTreeiENSGT00390000002397
HOGENOMiHOG000013172
HOVERGENiHBG100700
InParanoidiP0C2L3
OMAiAVHSHIP
OrthoDBiEOG091G0QQ1
PhylomeDBiP0C2L3
TreeFamiTF333084

Family and domain databases

InterProiView protein in InterPro
IPR029379 FAM163
PfamiView protein in Pfam
PF15069 FAM163, 1 hit

Sequencei

Sequence statusi: Complete.

P0C2L3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTAGTVVITG GILATVILLC IIAVLCYCRL QYYCCKKDES EEDEEEPDFA
60 70 80 90 100
VHSHLPPLHS NRNLVLTNGP ALYPTASTSF SQKSPQARAL CRSCSHCEPP
110 120 130 140 150
TFFLQEPPEE EEDVLNGGER VLYKSVSQED VELPPGGFGG LQALNPNRLS
160
AMREAFARSR SISTDV
Length:166
Mass (Da):18,190
Last modified:March 20, 2007 - v1
Checksum:iC048BBB4234EBC47
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX629352 Genomic DNA No translation available.
BC146946 mRNA Translation: AAI46947.1
BC146961 mRNA Translation: AAI46962.1
CCDSiCCDS35171.1
RefSeqiNP_001073984.1, NM_001080515.2
XP_005272260.1, XM_005272203.4
XP_005272261.1, XM_005272204.4
XP_006717296.1, XM_006717233.3
XP_011517214.1, XM_011518912.2
XP_011517215.1, XM_011518913.2
XP_016870506.1, XM_017015017.1
XP_016870507.1, XM_017015018.1
UniGeneiHs.173134
Hs.741379

Genome annotation databases

EnsembliENST00000356873; ENSP00000349336; ENSG00000196990
ENST00000496132; ENSP00000419867; ENSG00000196990
GeneIDi642968
KEGGihsa:642968
UCSCiuc011mdm.2 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX629352 Genomic DNA No translation available.
BC146946 mRNA Translation: AAI46947.1
BC146961 mRNA Translation: AAI46962.1
CCDSiCCDS35171.1
RefSeqiNP_001073984.1, NM_001080515.2
XP_005272260.1, XM_005272203.4
XP_005272261.1, XM_005272204.4
XP_006717296.1, XM_006717233.3
XP_011517214.1, XM_011518912.2
XP_011517215.1, XM_011518913.2
XP_016870506.1, XM_017015017.1
XP_016870507.1, XM_017015018.1
UniGeneiHs.173134
Hs.741379

3D structure databases

ProteinModelPortaliP0C2L3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP0C2L3, 2 interactors
MINTiP0C2L3
STRINGi9606.ENSP00000349336

PTM databases

iPTMnetiP0C2L3
PhosphoSitePlusiP0C2L3

Polymorphism and mutation databases

BioMutaiFAM163B
DMDMi134035404

Proteomic databases

PaxDbiP0C2L3
PeptideAtlasiP0C2L3
PRIDEiP0C2L3
ProteomicsDBi52303

Protocols and materials databases

DNASUi642968
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000356873; ENSP00000349336; ENSG00000196990
ENST00000496132; ENSP00000419867; ENSG00000196990
GeneIDi642968
KEGGihsa:642968
UCSCiuc011mdm.2 human

Organism-specific databases

CTDi642968
EuPathDBiHostDB:ENSG00000196990.8
GeneCardsiFAM163B
HGNCiHGNC:33277 FAM163B
HPAiHPA067336
neXtProtiNX_P0C2L3
OpenTargetsiENSG00000196990
PharmGKBiPA162386945
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IWU6 Eukaryota
ENOG4111P95 LUCA
GeneTreeiENSGT00390000002397
HOGENOMiHOG000013172
HOVERGENiHBG100700
InParanoidiP0C2L3
OMAiAVHSHIP
OrthoDBiEOG091G0QQ1
PhylomeDBiP0C2L3
TreeFamiTF333084

Miscellaneous databases

GenomeRNAii642968
PROiPR:P0C2L3

Gene expression databases

BgeeiENSG00000196990 Expressed in 68 organ(s), highest expression level in anterior cingulate cortex
CleanExiHS_FAM163B

Family and domain databases

InterProiView protein in InterPro
IPR029379 FAM163
PfamiView protein in Pfam
PF15069 FAM163, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF163B_HUMAN
AccessioniPrimary (citable) accession number: P0C2L3
Secondary accession number(s): B2RUZ5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: March 20, 2007
Last modified: September 12, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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