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Protein

Conotoxin Fi11.11

Gene
N/A
Organism
Conus figulinus (Fig cone)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionToxin

Names & Taxonomyi

Protein namesi
Recommended name:
Conotoxin Fi11.11
OrganismiConus figulinus (Fig cone)
Taxonomic identifieri101301 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaCaenogastropodaNeogastropodaConoideaConidaeConusDendroconus

Organism-specific databases

ConoServeri1456 Fi11.11 precursor

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_0000262681‹1 – 30Conotoxin Fi11.11Add BLAST›30
PropeptideiPRO_000026268235 – 4410

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi1 ↔ 15By similarity
Disulfide bondi8 ↔ 20By similarity
Disulfide bondi14 ↔ 24By similarity
Disulfide bondi19 ↔ 28By similarity
Modified residuei30Asparagine amideBy similarity1

Keywords - PTMi

Amidation, Cleavage on pair of basic residues, Disulfide bond

Expressioni

Tissue specificityi

Expressed by the venom duct.

Structurei

3D structure databases

SMRiP0C255
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

The cysteine framework is XI (C-C-CC-CC-C-C).

Sequence similaritiesi

Belongs to the conotoxin I2 superfamily.Curated

Family and domain databases

InterProiView protein in InterPro
IPR013141 Conotoxin-I_CS
IPR020242 Conotoxin_I2-superfamily
PfamiView protein in Pfam
PF17557 Conotoxin_I2, 1 hit
PROSITEiView protein in PROSITE
PS60019 I_CONOTOXIN, 1 hit

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0C255-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40 
CHHEGLPCTS GDGCCGMECC GGVCSSHCGN GRRRQVPLKS FGQR
Length:44
Mass (Da):4,611
Last modified:November 28, 2006 - v1
Checksum:iFC05BB10C40ACD96
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11

Cross-referencesi

3D structure databases

SMRiP0C255
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

ConoServeri1456 Fi11.11 precursor

Family and domain databases

InterProiView protein in InterPro
IPR013141 Conotoxin-I_CS
IPR020242 Conotoxin_I2-superfamily
PfamiView protein in Pfam
PF17557 Conotoxin_I2, 1 hit
PROSITEiView protein in PROSITE
PS60019 I_CONOTOXIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiI2BB_CONFI
AccessioniPrimary (citable) accession number: P0C255
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: November 28, 2006
Last modified: October 10, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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