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Protein

Sarcolemmal membrane-associated protein

Gene

Slmap

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May play a role during myoblast fusion.By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Sarcolemmal membrane-associated protein
Gene namesi
Name:Slmap
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1307674 Slmap

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 832CytoplasmicSequence analysisAdd BLAST832
Transmembranei833 – 853Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST21
Topological domaini854 – 858ExtracellularSequence analysis5

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Cytoskeleton, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002596651 – 858Sarcolemmal membrane-associated proteinAdd BLAST858

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei150PhosphoserineBy similarity1
Modified residuei472PhosphoserineCombined sources1
Modified residuei476PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiP0C219

PTM databases

iPTMnetiP0C219
PhosphoSitePlusiP0C219

Interactioni

Subunit structurei

Homodimer. Interacts with myosin (By similarity).By similarity

Structurei

3D structure databases

ProteinModelPortaliP0C219
SMRiP0C219
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 85FHAPROSITE-ProRule annotationAdd BLAST58

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 165Necessary for targeting to centrosomesBy similarityAdd BLAST165

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili169 – 204Sequence analysisAdd BLAST36
Coiled coili232 – 381Sequence analysisAdd BLAST150
Coiled coili516 – 829Sequence analysisAdd BLAST314

Sequence similaritiesi

Belongs to the SLMAP family.Curated

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000072709
HOVERGENiHBG082442
InParanoidiP0C219
PhylomeDBiP0C219

Family and domain databases

CDDicd00060 FHA, 1 hit
InterProiView protein in InterPro
IPR000253 FHA_dom
IPR030498 SLMAP
IPR008984 SMAD_FHA_dom_sf
PANTHERiPTHR15715:SF22 PTHR15715:SF22, 1 hit
PfamiView protein in Pfam
PF00498 FHA, 1 hit
SMARTiView protein in SMART
SM00240 FHA, 1 hit
SUPFAMiSSF49879 SSF49879, 1 hit
PROSITEiView protein in PROSITE
PS50006 FHA_DOMAIN, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.iShow all

P0C219-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPSALAIFTC RPNSHPFQER HVYLDEPIKI GRSVARCRPA QNNATFDCKV
60 70 80 90 100
LSRNHALVWF DHKTSKFYLQ DTKSSNGTFI NSQRLSRGSE ESPPCEILSG
110 120 130 140 150
DIIQFGVDVT ENTRKVVTHG CIVSTIKLFL PDGMEARLRS DDVIHAPLPS
160 170 180 190 200
PVDKVAANTP SMYSQELFQL SQYLQEALHR EQMLEQKLAT LQRLLAITQE
210 220 230 240 250
ASDTSWQALI DEDRLLSRLE VMGNQLQACS KNQTEDSLRK ELVALQEDKH
260 270 280 290 300
SYETTAKESL RRVLQEKIEV VRKLSEVERS LSNTEDECTH LREMNERTQE
310 320 330 340 350
ELRELANKYN GAVNEIKDLS DKLKAAEGKQ EEIQQKGQAE KKELQAKIDD
360 370 380 390 400
MEEKEQELQA KIEALQADND FTNERLTALQ VVRLEPLQEK TLKECSSLGG
410 420 430 440 450
IQVDDFLPKI NGSTEKEERL LSKSGGDCTF IHQFIECQKK KLMVQGHLTK
460 470 480 490 500
VVEESKLSKE ENQAKAKESD LSDTLSPSKE KSSDDTTDDA QMDEQDLNEP
510 520 530 540 550
LAKVSLLKDD DLQGTQAETE AKQDTQHLRK ELVEAQELAR ASKQKCFDLQ
560 570 580 590 600
AALLEEERKA YRNQVEESAK QIQVLQVVQL QRLHMDMENL QEEKDTEISS
610 620 630 640 650
TRDKLLSAQD EILLLHQAAA KAVSERDTDF MSLQEELKKV RAELEGWRKA
660 670 680 690 700
ASEYEEEIRS LQSTFQLRCQ QCEVQQREEA TRLQGGELEK LKKEWDVLEN
710 720 730 740 750
ECRSLKKENV LLSSELQRQE KELHNNSQKQ SLELTSDLSI LQMTRKELEN
760 770 780 790 800
QMGSLKEQHL RDEADLKTLL SKAENQAKDV QKEYEKTQTV LSELKLKFEM
810 820 830 840 850
TEQEKQSITD ELKQCKDNLK LLREKGNNKP WPWMPMVAAL VAVTAMVLYV

PGLARASP
Length:858
Mass (Da):98,224
Last modified:October 31, 2006 - v1
Checksum:i9BDAF795710C2FC9
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2JWA5A0A0G2JWA5_RAT
Sarcolemmal membrane-associated pro...
Slmap
808Annotation score:
D3ZKE6D3ZKE6_RAT
Sarcolemma associated protein (Pred...
Slmap Slmap_predicted, rCG_39165
787Annotation score:
B5DF63B5DF63_RAT
Sarcolemmal membrane-associated pro...
Slmap
749Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR03100912 Genomic DNA No translation available.
AABR03100133 Genomic DNA No translation available.
AABR03100672 Genomic DNA No translation available.
AABR03100596 Genomic DNA No translation available.
UniGeneiRn.3704

Genome annotation databases

UCSCiRGD:1307674 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR03100912 Genomic DNA No translation available.
AABR03100133 Genomic DNA No translation available.
AABR03100672 Genomic DNA No translation available.
AABR03100596 Genomic DNA No translation available.
UniGeneiRn.3704

3D structure databases

ProteinModelPortaliP0C219
SMRiP0C219
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiP0C219
PhosphoSitePlusiP0C219

Proteomic databases

PRIDEiP0C219

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiRGD:1307674 rat

Organism-specific databases

RGDi1307674 Slmap

Phylogenomic databases

HOGENOMiHOG000072709
HOVERGENiHBG082442
InParanoidiP0C219
PhylomeDBiP0C219

Miscellaneous databases

PROiPR:P0C219

Family and domain databases

CDDicd00060 FHA, 1 hit
InterProiView protein in InterPro
IPR000253 FHA_dom
IPR030498 SLMAP
IPR008984 SMAD_FHA_dom_sf
PANTHERiPTHR15715:SF22 PTHR15715:SF22, 1 hit
PfamiView protein in Pfam
PF00498 FHA, 1 hit
SMARTiView protein in SMART
SM00240 FHA, 1 hit
SUPFAMiSSF49879 SSF49879, 1 hit
PROSITEiView protein in PROSITE
PS50006 FHA_DOMAIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSLMAP_RAT
AccessioniPrimary (citable) accession number: P0C219
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 31, 2006
Last modified: May 23, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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