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UniProtKB - P0C1Z6 (TFPT_HUMAN)

Entry version 127 (07 Oct 2020)
Sequence version 1 (31 Oct 2006)
Previous versions | rss
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Protein

TCF3 fusion partner

Gene

TFPT

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Appears to promote apoptosis in a p53/TP53-independent manner.
Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processApoptosis, DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		P0C1Z6

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-5689603, UCH proteinases
R-HSA-5696394, DNA Damage Recognition in GG-NER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
TCF3 fusion partner
Alternative name(s):
INO80 complex subunit F
Protein FB1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TFPT
Synonyms:INO80F
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000105619.13

Human Gene Nomenclature Database

More...HGNCi		HGNC:13630, TFPT

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		609519, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P0C1Z6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

A chromosomal aberration involving TFPT is a cause of pre-B-cell acute lymphoblastic leukemia (B-ALL). Inversion inv(19)(p13;q13) with TCF3.1 Publication

Keywords - Diseasei

Proto-oncogene

Organism-specific databases

DisGeNET

More...DisGeNETi		29844

Open Targets

More...OpenTargetsi		ENSG00000105619

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA37802

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P0C1Z6, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		TFPT

Domain mapping of disease mutations (DMDM)

More...DMDMi		126352246

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002545811 – 253TCF3 fusion partnerAdd BLAST253

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei167PhosphoserineCombined sources1
Modified residuei172PhosphothreonineCombined sources1
Modified residuei180PhosphoserineCombined sources1
Modified residuei188PhosphoserineCombined sources1
Modified residuei207PhosphothreonineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki216Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei249PhosphoserineCombined sources1
Modified residuei252PhosphoserineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P0C1Z6

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P0C1Z6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P0C1Z6

MaxQB - The MaxQuant DataBase

More...MaxQBi		P0C1Z6

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P0C1Z6

PeptideAtlas

More...PeptideAtlasi		P0C1Z6

PRoteomics IDEntifications database

More...PRIDEi		P0C1Z6

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		33890
52299

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P0C1Z6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P0C1Z6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000105619, Expressed in prefrontal cortex and 209 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P0C1Z6, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P0C1Z6, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000105619, Tissue enhanced (brain)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with NOL3; translocates NOL3 into the nucleus and negatively regulated TFPT-induced cell death (By similarity).

Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the N-terminus of INO80.

By similarity3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		118931, 88 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-846, INO80 chromatin remodeling complex

Protein interaction database and analysis system

More...IntActi		P0C1Z6, 44 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000375639

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P0C1Z6, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502RHUP, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000016605

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P0C1Z6

KEGG Orthology (KO)

More...KOi		K11670

Identification of Orthologs from Complete Genome Data

More...OMAi		NEPPDKE

Database for complete collections of gene phylogenies

More...PhylomeDBi		P0C1Z6

TreeFam database of animal gene trees

More...TreeFami		TF338152

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR033555, TFPT

The PANTHER Classification System

More...PANTHERi		PTHR35084, PTHR35084, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P0C1Z6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MELEQREGTM AAVGFEEFSA PPGSELALPP LFGGHILESE LETEVEFVSG 
        60         70         80         90        100
GLGGSGLRER DEEEEAARGR RRRQRELNRR KYQALGRRCR EIEQVNERVL 
       110        120        130        140        150
NRLHQVQRIT RRLQQERRFL MRVLDSYGDD YRASQFTIVL EDEGSQGTDA 
       160        170        180        190        200
PTPGNAENEP PEKETLSPPR RTPAPPEPGS PAPGEGPSGR KRRRVPRDGR 
       210        220        230        240        250
RAGNALTPEL APVQIKVEED FGFEADEALD SSWVSRGPDK LLPYPTLASP 

ASD
Length:253
Mass (Da):28,278
Last modified:October 31, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC57CC8436F963F36
GO
Isoform 2 (identifier: P0C1Z6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-9: Missing.

Show »
Length:244
Mass (Da):27,204
Checksum:i671FF579304750CD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A8MTQ3A8MTQ3_HUMAN
TCF3 fusion partner
TFPT
193Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JP55A0A0G2JP55_HUMAN
TCF3 fusion partner
TFPT
145Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WDC1F8WDC1_HUMAN
TCF3 fusion partner
TFPT
105Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0589371 – 9Missing in isoform 2. 9

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF052052 mRNA Translation: AAD45182.1
AC012314 Genomic DNA No translation available.
AC245052 Genomic DNA No translation available.
CH471135 Genomic DNA Translation: EAW72186.1
BC001728 mRNA No translation available.
BC004281 mRNA Translation: AAH04281.1
BC007776 mRNA Translation: AAH07776.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS12878.1 [P0C1Z6-1]
CCDS82396.1 [P0C1Z6-2]

NCBI Reference Sequences

More...RefSeqi		NP_001308721.1, NM_001321792.1 [P0C1Z6-2]
NP_037474.1, NM_013342.3 [P0C1Z6-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000391758; ENSP00000375638; ENSG00000105619 [P0C1Z6-2]
ENST00000391759; ENSP00000375639; ENSG00000105619 [P0C1Z6-1]
ENST00000611344; ENSP00000484338; ENSG00000276504 [P0C1Z6-2]
ENST00000611514; ENSP00000481443; ENSG00000278161 [P0C1Z6-1]
ENST00000611935; ENSP00000482185; ENSG00000276022 [P0C1Z6-1]
ENST00000614788; ENSP00000482785; ENSG00000273833 [P0C1Z6-1]
ENST00000615534; ENSP00000480353; ENSG00000274073 [P0C1Z6-1]
ENST00000615620; ENSP00000483971; ENSG00000276263 [P0C1Z6-1]
ENST00000616277; ENSP00000483417; ENSG00000276296 [P0C1Z6-1]
ENST00000616798; ENSP00000480169; ENSG00000276504 [P0C1Z6-1]
ENST00000617348; ENSP00000477775; ENSG00000275086 [P0C1Z6-1]
ENST00000619581; ENSP00000484685; ENSG00000276323 [P0C1Z6-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		29844

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:29844

UCSC genome browser

More...UCSCi		uc010yej.1, human [P0C1Z6-1]
uc061cmq.1, human

Keywords - Coding sequence diversityi

Alternative splicing, Chromosomal rearrangement

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF052052 mRNA Translation: AAD45182.1
AC012314 Genomic DNA No translation available.
AC245052 Genomic DNA No translation available.
CH471135 Genomic DNA Translation: EAW72186.1
BC001728 mRNA No translation available.
BC004281 mRNA Translation: AAH04281.1
BC007776 mRNA Translation: AAH07776.1
CCDSiCCDS12878.1 [P0C1Z6-1]
CCDS82396.1 [P0C1Z6-2]
RefSeqiNP_001308721.1, NM_001321792.1 [P0C1Z6-2]
NP_037474.1, NM_013342.3 [P0C1Z6-1]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi118931, 88 interactors
ComplexPortaliCPX-846, INO80 chromatin remodeling complex
IntActiP0C1Z6, 44 interactors
STRINGi9606.ENSP00000375639

PTM databases

iPTMnetiP0C1Z6
PhosphoSitePlusiP0C1Z6

Polymorphism and mutation databases

BioMutaiTFPT
DMDMi126352246

Proteomic databases

EPDiP0C1Z6
jPOSTiP0C1Z6
MassIVEiP0C1Z6
MaxQBiP0C1Z6
PaxDbiP0C1Z6
PeptideAtlasiP0C1Z6
PRIDEiP0C1Z6
ProteomicsDBi33890
52299

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		32793, 148 antibodies

The DNASU plasmid repository

More...DNASUi		29844

Genome annotation databases

EnsembliENST00000391758; ENSP00000375638; ENSG00000105619 [P0C1Z6-2]
ENST00000391759; ENSP00000375639; ENSG00000105619 [P0C1Z6-1]
ENST00000611344; ENSP00000484338; ENSG00000276504 [P0C1Z6-2]
ENST00000611514; ENSP00000481443; ENSG00000278161 [P0C1Z6-1]
ENST00000611935; ENSP00000482185; ENSG00000276022 [P0C1Z6-1]
ENST00000614788; ENSP00000482785; ENSG00000273833 [P0C1Z6-1]
ENST00000615534; ENSP00000480353; ENSG00000274073 [P0C1Z6-1]
ENST00000615620; ENSP00000483971; ENSG00000276263 [P0C1Z6-1]
ENST00000616277; ENSP00000483417; ENSG00000276296 [P0C1Z6-1]
ENST00000616798; ENSP00000480169; ENSG00000276504 [P0C1Z6-1]
ENST00000617348; ENSP00000477775; ENSG00000275086 [P0C1Z6-1]
ENST00000619581; ENSP00000484685; ENSG00000276323 [P0C1Z6-1]
GeneIDi29844
KEGGihsa:29844
UCSCiuc010yej.1, human [P0C1Z6-1]
uc061cmq.1, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		29844
DisGeNETi29844
EuPathDBiHostDB:ENSG00000105619.13

GeneCards: human genes, protein and diseases

More...GeneCardsi		TFPT
HGNCiHGNC:13630, TFPT
HPAiENSG00000105619, Tissue enhanced (brain)
MIMi609519, gene
neXtProtiNX_P0C1Z6
OpenTargetsiENSG00000105619
PharmGKBiPA37802

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502RHUP, Eukaryota
GeneTreeiENSGT00390000016605
InParanoidiP0C1Z6
KOiK11670
OMAiNEPPDKE
PhylomeDBiP0C1Z6
TreeFamiTF338152

Enzyme and pathway databases

PathwayCommonsiP0C1Z6
ReactomeiR-HSA-5689603, UCH proteinases
R-HSA-5696394, DNA Damage Recognition in GG-NER

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		29844, 61 hits in 884 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		TFPT, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		TFPT

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		29844
PharosiP0C1Z6, Tbio

Protein Ontology

More...PROi		PR:P0C1Z6
RNActiP0C1Z6, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000105619, Expressed in prefrontal cortex and 209 other tissues
ExpressionAtlasiP0C1Z6, baseline and differential
GenevisibleiP0C1Z6, HS

Family and domain databases

InterProiView protein in InterPro
IPR033555, TFPT
PANTHERiPTHR35084, PTHR35084, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTFPT_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P0C1Z6
Secondary accession number(s): G5E9B5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 31, 2006
Last modified: October 7, 2020
This is version 127 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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