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Protein

Transmembrane and coiled-coil domain-containing protein 2

Gene

Tmco2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane and coiled-coil domain-containing protein 2
Gene namesi
Name:Tmco2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:1916719 Tmco2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei54 – 74HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002494361 – 183Transmembrane and coiled-coil domain-containing protein 2Add BLAST183

Proteomic databases

EPDiP0C1V4
PaxDbiP0C1V4
PRIDEiP0C1V4

PTM databases

iPTMnetiP0C1V4
PhosphoSitePlusiP0C1V4

Expressioni

Gene expression databases

CleanExiMM_TMCO2

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000101875

Structurei

3D structure databases

SMRiP0C1V4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili127 – 150Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410JA7Q Eukaryota
ENOG4111526 LUCA
HOGENOMiHOG000154635
HOVERGENiHBG080208
InParanoidiP0C1V4

Family and domain databases

InterProiView protein in InterPro
IPR031697 TMCCDC2
PANTHERiPTHR38496 PTHR38496, 1 hit
PfamiView protein in Pfam
PF15844 TMCCDC2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P0C1V4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPTFPTTTSS WDNLLNALAR SSIWNWLQAM FIGETTSAPQ PTNLGILDNL
60 70 80 90 100
APAVQIILGI SFLTLLAIGL FALWKRSIRS IQKIVMFVIT LYQLYKKGSD
110 120 130 140 150
FFQVLLANPE GSGRQIQDNN NIFLSLGLQE KILKKLQMVE NKVRDLEGII
160 170 180
VARKPASKRD CSSEPYCSCS DCQSPLPTSG FTS
Length:183
Mass (Da):20,331
Last modified:September 19, 2006 - v1
Checksum:iF17790D57EF7EECD
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3JS82J3JS82_MOUSE
MCG49082
Tmco2 mCG_49082
187Annotation score:

Sequence cautioni

The sequence AK006456 differs from that shown. Reason: Erroneous termination at position 99. Translated as Ser.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti156A → G (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK006456 mRNA No translation available.
AL669949 Genomic DNA No translation available.
UniGeneiMm.481120

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK006456 mRNA No translation available.
AL669949 Genomic DNA No translation available.
UniGeneiMm.481120

3D structure databases

SMRiP0C1V4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000101875

PTM databases

iPTMnetiP0C1V4
PhosphoSitePlusiP0C1V4

Proteomic databases

EPDiP0C1V4
PaxDbiP0C1V4
PRIDEiP0C1V4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1916719 Tmco2

Phylogenomic databases

eggNOGiENOG410JA7Q Eukaryota
ENOG4111526 LUCA
HOGENOMiHOG000154635
HOVERGENiHBG080208
InParanoidiP0C1V4

Miscellaneous databases

PROiPR:P0C1V4
SOURCEiSearch...

Gene expression databases

CleanExiMM_TMCO2

Family and domain databases

InterProiView protein in InterPro
IPR031697 TMCCDC2
PANTHERiPTHR38496 PTHR38496, 1 hit
PfamiView protein in Pfam
PF15844 TMCCDC2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTMCO2_MOUSE
AccessioniPrimary (citable) accession number: P0C1V4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: September 19, 2006
Last modified: February 28, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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