The new UniProt website is here!
Take me to UniProt BETA
UniProtKB - P0C0K9 (NAC_METTM)
Protein
Nascent polypeptide-associated complex protein
Gene
nac
Organism
Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum)
Status
Functioni
Contacts the emerging nascent chain on the ribosome.
UniRule annotationGO - Molecular functioni
- RNA binding Source: UniProtKB-UniRule
GO - Biological processi
- protein transport Source: UniProtKB-UniRule
Keywordsi
Molecular function | RNA-binding |
Biological process | Protein transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Nascent polypeptide-associated complex proteinUniRule annotation |
Gene namesi | Name:nacUniRule annotation Ordered Locus Names:MTBMA_c06300 |
Organismi | Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) |
Taxonomic identifieri | 79929 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Methanomada group › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000135600 | 1 – 117 | Nascent polypeptide-associated complex proteinAdd BLAST | 117 |
Interactioni
Subunit structurei
Homodimer.
Interacts with the ribosome. Binds ribosomal RNA.
UniRule annotation1 PublicationProtein-protein interaction databases
STRINGi | 79929.MTBMA_c06300 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
AlphaFoldDBi | P0C0K9 |
SMRi | P0C0K9 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P0C0K9 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 9 – 77 | NAC-A/BUniRule annotationAdd BLAST | 69 |
Sequence similaritiesi
Belongs to the NAC-alpha family.UniRule annotation
Phylogenomic databases
HOGENOMi | CLU_146475_0_0_2 |
OMAi | PRKMKQM |
OrthoDBi | 105165at2157 |
Family and domain databases
Gene3Di | 2.20.70.30, 1 hit |
HAMAPi | MF_00814, NAC_arch, 1 hit |
IDEALi | IID90013 |
InterProi | View protein in InterPro IPR044034, NAC-like_UBA IPR038187, NAC_A/B_dom_sf IPR005231, NAC_arc IPR002715, Nas_poly-pep-assoc_cplx_dom IPR009060, UBA-like_sf |
Pfami | View protein in Pfam PF19026, HYPK_UBA, 1 hit PF01849, NAC, 1 hit |
SMARTi | View protein in SMART SM01407, NAC, 1 hit |
SUPFAMi | SSF46934, SSF46934, 1 hit |
TIGRFAMsi | TIGR00264, TIGR00264, 1 hit |
PROSITEi | View protein in PROSITE PS51151, NAC_AB, 1 hit |
i Sequence
Sequence statusi: Complete.
P0C0K9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIPGMGMNPK QLKQMQRAMK QMGMDMKDLR GVEEVVIKLK KKEIIIKNPR
60 70 80 90 100
VNVMDFMGQK TYQVTGKARE CDLEAEVKIP DDDIELVMNQ TGVSREEATR
110
ALQETGGDLA EAIMRLS
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 41 | K → R no nucleotide entry (PubMed:15665334).Curated | 1 | |
Sequence conflicti | 50 | R → K no nucleotide entry (PubMed:15665334).Curated | 1 | |
Sequence conflicti | 55 | D → E no nucleotide entry (PubMed:15665334).Curated | 1 | |
Sequence conflicti | 71 – 72 | CD → RS no nucleotide entry (PubMed:15665334).Curated | 2 | |
Sequence conflicti | 77 – 78 | VK → ME no nucleotide entry (PubMed:15665334).Curated | 2 | |
Sequence conflicti | 81 | D → E no nucleotide entry (PubMed:15665334).Curated | 1 | |
Sequence conflicti | 93 | V → A no nucleotide entry (PubMed:15665334).Curated | 1 | |
Sequence conflicti | 97 | E → D no nucleotide entry (PubMed:15665334).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP001710 Genomic DNA Translation: ADL58225.1 |
RefSeqi | WP_013295449.1, NC_014408.1 |
Genome annotation databases
EnsemblBacteriai | ADL58225; ADL58225; MTBMA_c06300 |
GeneIDi | 9704338 |
KEGGi | mmg:MTBMA_c06300 |
PATRICi | fig|79929.8.peg.614 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP001710 Genomic DNA Translation: ADL58225.1 |
RefSeqi | WP_013295449.1, NC_014408.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1TR8 | X-ray | 2.27 | A/B | 19-117 | [»] | |
AlphaFoldDBi | P0C0K9 | |||||
SMRi | P0C0K9 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 79929.MTBMA_c06300 |
Genome annotation databases
EnsemblBacteriai | ADL58225; ADL58225; MTBMA_c06300 |
GeneIDi | 9704338 |
KEGGi | mmg:MTBMA_c06300 |
PATRICi | fig|79929.8.peg.614 |
Phylogenomic databases
HOGENOMi | CLU_146475_0_0_2 |
OMAi | PRKMKQM |
OrthoDBi | 105165at2157 |
Miscellaneous databases
EvolutionaryTracei | P0C0K9 |
Family and domain databases
Gene3Di | 2.20.70.30, 1 hit |
HAMAPi | MF_00814, NAC_arch, 1 hit |
IDEALi | IID90013 |
InterProi | View protein in InterPro IPR044034, NAC-like_UBA IPR038187, NAC_A/B_dom_sf IPR005231, NAC_arc IPR002715, Nas_poly-pep-assoc_cplx_dom IPR009060, UBA-like_sf |
Pfami | View protein in Pfam PF19026, HYPK_UBA, 1 hit PF01849, NAC, 1 hit |
SMARTi | View protein in SMART SM01407, NAC, 1 hit |
SUPFAMi | SSF46934, SSF46934, 1 hit |
TIGRFAMsi | TIGR00264, TIGR00264, 1 hit |
PROSITEi | View protein in PROSITE PS51151, NAC_AB, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | NAC_METTM | |
Accessioni | P0C0K9Primary (citable) accession number: P0C0K9 Secondary accession number(s): D9PVH7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 25, 2005 |
Last sequence update: | November 30, 2010 | |
Last modified: | May 25, 2022 | |
This is version 77 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structureDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families