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Protein

Dihydropteroate synthase type-1

Gene

sulI

Organism
Escherichia coli
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives (By similarity). It is implicated in resistance to sulfonamide. The type II enzyme is stable whereas type I DHPS loses its activity rapidly.By similarity

Miscellaneous

The sulI gene is located on various large self-transmissible resistance plasmids and on transposons related to Tn21.
The plasmid pDGO100 contains two copies of the sulI gene.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: tetrahydrofolate biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate.
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Dihydropteroate synthase (sul2), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP), Dihydropteroate synthase (C2U48_30365), Dihydropteroate synthase (CRM83_20785), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP), Dihydropteroate synthase (CCZ08_16730), Dihydropteroate synthase (sul3), Dihydropteroate synthase (C1I39_27460), Dihydropteroate synthase (sulI), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP), Dihydropteroate synthase (sul2), Dihydropteroate synthase (sul1), Dihydropteroate synthase (folP), Dihydropteroate synthase (sulII), Dihydropteroate synthase (B634_00023), Dihydropteroate synthase (SulI), Dihydropteroate synthase (CWS33_26340), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP), Dihydropteroate synthase (DXF93_01780), Dihydropteroate synthase (BK375_28220), Dihydropteroate synthase (folP), Dihydropteroate synthase (B9N33_26330), Dihydropteroate synthase (folP), Dihydropteroate synthase (DS732_23625), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP_1), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP), Dihydropteroate synthase (BK383_15895), Dihydropteroate synthase (CRT55_03920), Dihydropteroate synthase (folP), Dihydropteroate synthase (sul1), Dihydropteroate synthase (BMR23_11675), Dihydropteroate synthase (folP), Dihydropteroate synthase (A9819_18240), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP), Dihydropteroate synthase (BXT93_15530), Dihydropteroate synthase (AW059_15240), Dihydropteroate synthase (ACN81_18515), Dihydropteroate synthase (APU18_05315), Dihydropteroate synthase (C2U48_30480), Dihydropteroate synthase (BMT49_25665), Dihydropteroate synthase (C6985_19500), Dihydropteroate synthase (sulI), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP2), Dihydropteroate synthase (C5P01_18905), Dihydropteroate synthase (folP), Dihydropteroate synthase (BK400_32640), Dihydropteroate synthase type-1 (sulI), Dihydropteroate synthase type-2 (sulII), Dihydropteroate synthase (sul1), Dihydropteroate synthase, Dihydropteroate synthase, Dihydropteroate synthase (sul2), Dihydropteroate synthase (BSR05_04210), Dihydropteroate synthase, Dihydropteroate synthase (folP), Dihydropteroate synthase, Dihydropteroate synthase (sul1), Dihydropteroate synthase, Dihydropteroate synthase (sul2), Dihydropteroate synthase (sulII), Dihydropteroate synthase, Dihydropteroate synthase (folP), Dihydropteroate synthase (folP), Dihydropteroate synthase (folP_3), Dihydropteroate synthase (sul3), Dihydropteroate synthase (sul2), Dihydropteroate synthase (folP_1), Dihydropteroate synthase (sul1), Dihydropteroate synthase (sul3), Dihydropteroate synthase (sul1)
  2. no protein annotated in this organism
This subpathway is part of the pathway tetrahydrofolate biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate, the pathway tetrahydrofolate biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi9MagnesiumBy similarity1
<p>This subsection of the ‘Function’ section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei826-hydroxymethyl-7,8-dihydropterin diphosphateBy similarity1
Binding sitei1016-hydroxymethyl-7,8-dihydropterin diphosphateBy similarity1
Binding sitei1736-hydroxymethyl-7,8-dihydropterin diphosphateBy similarity1
Binding sitei2126-hydroxymethyl-7,8-dihydropterin diphosphateBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferase
Biological processAntibiotic resistance, Folate biosynthesis
LigandMagnesium, Metal-binding

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00077;UER00156

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Dihydropteroate synthase type-1 (EC:2.5.1.15)
Alternative name(s):
Dihydropteroate pyrophosphorylase type I
Dihydropteroate synthase type I
Short name:
DHPS
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:sulI
Synonyms:sul1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates if the gene coding for the protein originates from the hydrogenosome, the mitochondrion, the nucleomorph, different plastids or a plasmid. The absence of this section means that the gene is located in one of the main chromosomal element(s).<p><a href='/help/encoded_on' target='_top'>More...</a></p>Encoded oniPlasmid IncFII R100 (NR1)1 Publication
Plasmid IncW R3882 Publications
Plasmid pLMO201 Publication
Plasmid pLMO271 Publication
Plasmid IncN R462 Publications
Plasmid pDGO1001 Publication
Plasmid R6-51 Publication
Plasmid pDGO1011 Publication
Plasmid IncFII NR791 Publication
Plasmid IncW pSa3 Publications
Plasmid IncP-beta R7511 Publication
Plasmid pCMXR11 Publication
Plasmid pMSP0711 Publication
Plasmid p1658/971 Publication
Plasmid pHSH11 Publication
Plasmid pHSH21 Publication
Plasmid pAK331 Publication
Plasmid p5411 Publication
Plasmid pQR-11 Publication
Plasmid pKO561 Publication
Plasmid pKO971 Publication
Plasmid pAPEC-O2-R1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri562 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB00634 Sulfacetamide

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001682011 – 279Dihydropteroate synthase type-1Add BLAST279

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer or homotrimer.

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P0C002

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P0C002

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 258Pterin-bindingPROSITE-ProRule annotationAdd BLAST258

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni246 – 2486-hydroxymethyl-7,8-dihydropterin diphosphate bindingBy similarity3

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DHPS family.Curated

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00739 DHPS, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.20.20.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006390 DHP_synth
IPR011005 Dihydropteroate_synth-like
IPR000489 Pterin-binding_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00809 Pterin_bind, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51717 SSF51717, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01496 DHPS, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00792 DHPS_1, 1 hit
PS00793 DHPS_2, 1 hit
PS50972 PTERIN_BINDING, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P0C002-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVTVFGILNL TEDSFFDESR RLDPAGAVTA AIEMLRVGSD VVDVGPAASH
60 70 80 90 100
PDARPVSPAD EIRRIAPLLD ALSDQMHRVS IDSFQPETQR YALKRGVGYL
110 120 130 140 150
NDIQGFPDPA LYPDIAEADC RLVVMHSAQR DGIATRTGHL RPEDALDEIV
160 170 180 190 200
RFFEARVSAL RRSGVAADRL ILDPGMGFFL SPAPETSLHV LSNLQKLKSA
210 220 230 240 250
LGLPLLVSVS RKSFLGATVG LPVKDLGPAS LAAELHAIGN GADYVRTHAP
260 270
GDLRSAITFS ETLAKFRSRD ARDRGLDHA
Length:279
Mass (Da):30,126
Last modified:June 7, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i13EE36C6E3FBDF63
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti259F → I in CAA00729 (PubMed:2662140).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X12868 Genomic DNA Translation: CAA31358.1
M95287 Genomic DNA Translation: AAB59087.1
U42226 Genomic DNA Translation: AAC53726.1
X15024 Genomic DNA Translation: CAA33123.1
A07921 Unassigned DNA Translation: CAA00729.1
X12870 Genomic DNA Translation: CAA31364.1
AF047479 Genomic DNA Translation: AAC14739.1
L06418 Genomic DNA Translation: AAA92747.1
L06418 Genomic DNA Translation: AAA92751.3
U04277 Genomic DNA Translation: AAB60179.1
AF071413 Genomic DNA Translation: AAC33914.1
AF205943 Genomic DNA Translation: AAG45723.1
U12441 Genomic DNA Translation: AAK95985.1
AB061794 Genomic DNA Translation: BAB72156.1
AF174129 Genomic DNA Translation: AAK60189.2
AF550679 Genomic DNA Translation: AAO49595.1
AY259085 Genomic DNA Translation: AAP20908.1
AY259085 Genomic DNA Translation: AAP20913.1
AY259086 Genomic DNA Translation: AAP20924.1
AY259086 Genomic DNA Translation: AAP20929.1
AY224185 Genomic DNA Translation: AAP51287.1
AY260546 Genomic DNA Translation: AAP22979.1
AY339625 Genomic DNA Translation: AAQ16671.1
L06822 Genomic DNA Translation: AAW29415.1
L06822 Genomic DNA Translation: AAW29418.1
AY655485 Genomic DNA Translation: AAW31097.1
AY878717 Genomic DNA Translation: AAX18266.1
AY878717 Genomic DNA Translation: AAX18269.1
AY878718 Genomic DNA Translation: AAX18276.1
AY878718 Genomic DNA Translation: AAX18279.1
AY214164 Genomic DNA Translation: AAP51280.1
X58425 Genomic DNA Translation: CAA41328.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A60174 SYECOG
T45123

NCBI Reference Sequences

More...
RefSeqi
NP_863000.1, NC_004998.1
WP_000259031.1, NZ_UIMZ01000083.1
YP_001096354.1, NC_009132.1
YP_001096411.1, NC_009133.1
YP_002891164.1, NC_012690.1
YP_002894492.1, NC_012692.1
YP_003937681.1, NC_014615.1
YP_004558213.1, NC_015599.1
YP_006902980.1, NC_019037.1
YP_006903340.1, NC_019045.2
YP_006939957.1, NC_018994.1
YP_006952407.1, NC_019062.1
YP_006952437.1, NC_019063.1
YP_006952978.1, NC_019066.1
YP_006953197.1, NC_019069.1
YP_006953612.1, NC_019081.1
YP_006953620.1, NC_019082.1
YP_008574825.1, NC_022374.1
YP_009023104.1, NC_023909.1
YP_009060115.1, NC_024956.1
YP_009061085.1, NC_024975.1
YP_009068292.1, NC_025139.1
YP_009070794.1, NC_025175.1
YP_009182147.1, NC_028464.1
YP_190215.1, NC_006671.1
YP_724471.1, NC_007682.3

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10752055
13876924
13900729
13903449
13905341
13905373
13905882
13906105
13906547
13906557
1446559
17035641
18983605
20466880
20468108
20491422
20492862
29200589
3244835
4246764
4924679
4924736
4999104
7872397
7872757
9846098

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X12868 Genomic DNA Translation: CAA31358.1
M95287 Genomic DNA Translation: AAB59087.1
U42226 Genomic DNA Translation: AAC53726.1
X15024 Genomic DNA Translation: CAA33123.1
A07921 Unassigned DNA Translation: CAA00729.1
X12870 Genomic DNA Translation: CAA31364.1
AF047479 Genomic DNA Translation: AAC14739.1
L06418 Genomic DNA Translation: AAA92747.1
L06418 Genomic DNA Translation: AAA92751.3
U04277 Genomic DNA Translation: AAB60179.1
AF071413 Genomic DNA Translation: AAC33914.1
AF205943 Genomic DNA Translation: AAG45723.1
U12441 Genomic DNA Translation: AAK95985.1
AB061794 Genomic DNA Translation: BAB72156.1
AF174129 Genomic DNA Translation: AAK60189.2
AF550679 Genomic DNA Translation: AAO49595.1
AY259085 Genomic DNA Translation: AAP20908.1
AY259085 Genomic DNA Translation: AAP20913.1
AY259086 Genomic DNA Translation: AAP20924.1
AY259086 Genomic DNA Translation: AAP20929.1
AY224185 Genomic DNA Translation: AAP51287.1
AY260546 Genomic DNA Translation: AAP22979.1
AY339625 Genomic DNA Translation: AAQ16671.1
L06822 Genomic DNA Translation: AAW29415.1
L06822 Genomic DNA Translation: AAW29418.1
AY655485 Genomic DNA Translation: AAW31097.1
AY878717 Genomic DNA Translation: AAX18266.1
AY878717 Genomic DNA Translation: AAX18269.1
AY878718 Genomic DNA Translation: AAX18276.1
AY878718 Genomic DNA Translation: AAX18279.1
AY214164 Genomic DNA Translation: AAP51280.1
X58425 Genomic DNA Translation: CAA41328.1
PIRiA60174 SYECOG
T45123
RefSeqiNP_863000.1, NC_004998.1
WP_000259031.1, NZ_UIMZ01000083.1
YP_001096354.1, NC_009132.1
YP_001096411.1, NC_009133.1
YP_002891164.1, NC_012690.1
YP_002894492.1, NC_012692.1
YP_003937681.1, NC_014615.1
YP_004558213.1, NC_015599.1
YP_006902980.1, NC_019037.1
YP_006903340.1, NC_019045.2
YP_006939957.1, NC_018994.1
YP_006952407.1, NC_019062.1
YP_006952437.1, NC_019063.1
YP_006952978.1, NC_019066.1
YP_006953197.1, NC_019069.1
YP_006953612.1, NC_019081.1
YP_006953620.1, NC_019082.1
YP_008574825.1, NC_022374.1
YP_009023104.1, NC_023909.1
YP_009060115.1, NC_024956.1
YP_009061085.1, NC_024975.1
YP_009068292.1, NC_025139.1
YP_009070794.1, NC_025175.1
YP_009182147.1, NC_028464.1
YP_190215.1, NC_006671.1
YP_724471.1, NC_007682.3

3D structure databases

ProteinModelPortaliP0C002
SMRiP0C002
ModBaseiSearch...
MobiDBiSearch...

Chemistry databases

DrugBankiDB00634 Sulfacetamide

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10752055
13876924
13900729
13903449
13905341
13905373
13905882
13906105
13906547
13906557
1446559
17035641
18983605
20466880
20468108
20491422
20492862
29200589
3244835
4246764
4924679
4924736
4999104
7872397
7872757
9846098

Enzyme and pathway databases

UniPathwayi
UPA00077;UER00156

Family and domain databases

CDDicd00739 DHPS, 1 hit
Gene3Di3.20.20.20, 1 hit
InterProiView protein in InterPro
IPR006390 DHP_synth
IPR011005 Dihydropteroate_synth-like
IPR000489 Pterin-binding_dom
PfamiView protein in Pfam
PF00809 Pterin_bind, 1 hit
SUPFAMiSSF51717 SSF51717, 1 hit
TIGRFAMsiTIGR01496 DHPS, 1 hit
PROSITEiView protein in PROSITE
PS00792 DHPS_1, 1 hit
PS00793 DHPS_2, 1 hit
PS50972 PTERIN_BINDING, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDHP1_ECOLX
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P0C002
Secondary accession number(s): P11744, Q79LJ7, Q93K51
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: December 5, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Plasmid, Transposable element

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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