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UniProtKB - P0AG88 (SECB_ECO57)
Protein
Protein-export protein SecB
Gene
secB
Organism
Escherichia coli O157:H7
Status
Functioni
One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
UniRule annotationGO - Molecular functioni
- unfolded protein binding Source: InterPro
GO - Biological processi
- protein folding Source: UniProtKB-UniRule
- protein tetramerization Source: InterPro
- protein transport Source: UniProtKB-UniRule
Keywordsi
Molecular function | Chaperone |
Biological process | Protein transport, Translocation, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Protein-export protein SecBUniRule annotation |
Gene namesi | Name:secBUniRule annotation Ordered Locus Names:Z5036, ECs4487 |
Organismi | Escherichia coli O157:H7 |
Taxonomic identifieri | 83334 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm UniRule annotation
Other locations
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000055371 | 1 – 155 | Protein-export protein SecBAdd BLAST | 155 |
Interactioni
Subunit structurei
Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
UniRule annotationGO - Molecular functioni
- unfolded protein binding Source: InterPro
Protein-protein interaction databases
STRINGi | 155864.EDL933_4873 |
Family & Domainsi
Sequence similaritiesi
Belongs to the SecB family.UniRule annotation
Phylogenomic databases
eggNOGi | COG1952, Bacteria |
HOGENOMi | CLU_111574_1_0_6 |
OMAi | CPNVLFP |
Family and domain databases
Gene3Di | 3.10.420.10, 1 hit |
HAMAPi | MF_00821, SecB, 1 hit |
InterProi | View protein in InterPro IPR003708, SecB IPR035958, SecB-like_sf |
PANTHERi | PTHR36918, PTHR36918, 1 hit |
Pfami | View protein in Pfam PF02556, SecB, 1 hit |
PRINTSi | PR01594, SECBCHAPRONE |
SUPFAMi | SSF54611, SSF54611, 1 hit |
TIGRFAMsi | TIGR00809, secB, 1 hit |
i Sequence
Sequence statusi: Complete.
P0AG88-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSEQNNTEMT FQIQRIYTKD ISFEAPNAPH VFQKDWQPEV KLDLDTASSQ
60 70 80 90 100
LADDVYEVVL RVTVTASLGE ETAFLCEVQQ GGIFSIAGIE GTQMAHCLGA
110 120 130 140 150
YCPNILFPYA RECITSMVSR GTFPQLNLAP VNFDALFMNY LQQQAGEGTE
EHQDA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE005174 Genomic DNA Translation: AAG58756.1 BA000007 Genomic DNA Translation: BAB37910.1 |
PIRi | G91189 H86036 |
RefSeqi | NP_312514.1, NC_002695.1 WP_000003377.1, NZ_SWKA01000005.1 |
Genome annotation databases
EnsemblBacteriai | AAG58756; AAG58756; Z5036 BAB37910; BAB37910; ECs_4487 |
GeneIDi | 67417612 915570 |
KEGGi | ece:Z5036 ecs:ECs4487 |
PATRICi | fig|386585.9.peg.4702 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE005174 Genomic DNA Translation: AAG58756.1 BA000007 Genomic DNA Translation: BAB37910.1 |
PIRi | G91189 H86036 |
RefSeqi | NP_312514.1, NC_002695.1 WP_000003377.1, NZ_SWKA01000005.1 |
3D structure databases
AlphaFoldDBi | P0AG88 |
SMRi | P0AG88 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 155864.EDL933_4873 |
Genome annotation databases
EnsemblBacteriai | AAG58756; AAG58756; Z5036 BAB37910; BAB37910; ECs_4487 |
GeneIDi | 67417612 915570 |
KEGGi | ece:Z5036 ecs:ECs4487 |
PATRICi | fig|386585.9.peg.4702 |
Phylogenomic databases
eggNOGi | COG1952, Bacteria |
HOGENOMi | CLU_111574_1_0_6 |
OMAi | CPNVLFP |
Family and domain databases
Gene3Di | 3.10.420.10, 1 hit |
HAMAPi | MF_00821, SecB, 1 hit |
InterProi | View protein in InterPro IPR003708, SecB IPR035958, SecB-like_sf |
PANTHERi | PTHR36918, PTHR36918, 1 hit |
Pfami | View protein in Pfam PF02556, SecB, 1 hit |
PRINTSi | PR01594, SECBCHAPRONE |
SUPFAMi | SSF54611, SSF54611, 1 hit |
TIGRFAMsi | TIGR00809, secB, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | SECB_ECO57 | |
Accessioni | P0AG88Primary (citable) accession number: P0AG88 Secondary accession number(s): P15040 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 20, 2005 |
Last sequence update: | December 20, 2005 | |
Last modified: | May 25, 2022 | |
This is version 94 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families