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Protein

30S ribosomal protein S14

Gene

rpsN

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.

GO - Molecular functioni

  • structural constituent of ribosome Source: CAFA

GO - Biological processi

  • ribosomal small subunit assembly Source: CAFA
  • translation Source: GO_Central

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciEcoCyc:EG10913-MONOMER
MetaCyc:EG10913-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S14
Alternative name(s):
Small ribosomal subunit protein uS141 Publication
Gene namesi
Name:rpsN
Ordered Locus Names:b3307, JW3269
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10913 rpsN

Subcellular locationi

GO - Cellular componenti

  • cytosolic small ribosomal subunit Source: CAFA

Pathology & Biotechi

Chemistry databases

DrugBankiDB00759 Tetracycline
DB00560 Tigecycline

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved
ChainiPRO_00001308902 – 10130S ribosomal protein S14Add BLAST100

Proteomic databases

EPDiP0AG59
PaxDbiP0AG59
PRIDEiP0AG59

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit (PubMed:10094780, PubMed:12809609, PubMed:16272117, PubMed:27934701, PubMed:12244297, PubMed:27906160, PubMed:27906161). Contacts proteins S3 and S10 (By similarity).UniRule annotation7 Publications

Protein-protein interaction databases

DIPiDIP-35805N
IntActiP0AG59, 82 interactors
STRINGi316385.ECDH10B_3482

Structurei

Secondary structure

1101
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi4 – 19Combined sources16
Turni20 – 23Combined sources4
Helixi24 – 26Combined sources3
Helixi27 – 29Combined sources3
Helixi30 – 32Combined sources3
Helixi44 – 47Combined sources4
Turni49 – 52Combined sources4
Helixi53 – 55Combined sources3
Helixi57 – 59Combined sources3
Turni65 – 67Combined sources3
Beta strandi71 – 74Combined sources4
Turni75 – 78Combined sources4
Helixi81 – 88Combined sources8
Turni89 – 91Combined sources3
Beta strandi93 – 95Combined sources3
Beta strandi96 – 98Combined sources3

3D structure databases

ProteinModelPortaliP0AG59
SMRiP0AG59
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0AG59

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105VBI Bacteria
COG0199 LUCA
HOGENOMiHOG000039864
InParanoidiP0AG59
KOiK02954
OMAiRLHNRCK
PhylomeDBiP0AG59

Family and domain databases

HAMAPiMF_00537 Ribosomal_S14_1, 1 hit
InterProiView protein in InterPro
IPR001209 Ribosomal_S14
IPR023036 Ribosomal_S14_bac/plastid
IPR018271 Ribosomal_S14_CS
PANTHERiPTHR19836 PTHR19836, 1 hit
PfamiView protein in Pfam
PF00253 Ribosomal_S14, 1 hit
PROSITEiView protein in PROSITE
PS00527 RIBOSOMAL_S14, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0AG59-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKQSMKARE VKRVALADKY FAKRAELKAI ISDVNASDED RWNAVLKLQT
60 70 80 90 100
LPRDSSPSRQ RNRCRQTGRP HGFLRKFGLS RIKVREAAMR GEIPGLKKAS

W
Length:101
Mass (Da):11,580
Last modified:January 23, 2007 - v2
Checksum:iE2B21D9D3752352C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti92E → Q AA sequence (Ref. 1) Curated1
Sequence conflicti99 – 101ASW → G in CAA25718 (PubMed:6222285).Curated3

Mass spectrometryi

Molecular mass is 11449.3 Da from positions 2 - 101. Determined by MALDI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X01563 Genomic DNA Translation: CAA25718.1
U18997 Genomic DNA Translation: AAA58104.1
U00096 Genomic DNA Translation: AAC76332.1
AP009048 Genomic DNA Translation: BAE77984.1
PIRiF65123 R3EC14
RefSeqiNP_417766.1, NC_000913.3
WP_001118930.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76332; AAC76332; b3307
BAE77984; BAE77984; BAE77984
GeneIDi947801
KEGGiecj:JW3269
eco:b3307
PATRICifig|1411691.4.peg.3424

Similar proteinsi

Entry informationi

Entry nameiRS14_ECOLI
AccessioniPrimary (citable) accession number: P0AG59
Secondary accession number(s): P02370, Q2M6X2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: June 20, 2018
This is version 124 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

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