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Protein

50S ribosomal protein L21

Gene

rplU

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

This protein binds to 23S rRNA in the presence of protein L20.2 Publications

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:EG50001-MONOMER
MetaCyc:EG50001-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L21UniRule annotation
Alternative name(s):
Large ribosomal subunit protein bL211 Publication
Gene namesi
Name:rplUUniRule annotation
Ordered Locus Names:b3186, JW3153
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG50001 rplU

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
  • cytosolic large ribosomal subunit Source: EcoCyc

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001810001 – 10350S ribosomal protein L21Add BLAST103

Proteomic databases

EPDiP0AG48
PaxDbiP0AG48
PRIDEiP0AG48

2D gel databases

SWISS-2DPAGEiP0AG48

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit (PubMed:387076, PubMed:10094780, PubMed:16272117, PubMed:25310980, PubMed:24844575, PubMed:27934701, PubMed:27906160, PubMed:27906161). Contacts protein L20 (PubMed:2665813, PubMed:6170935).9 Publications

Protein-protein interaction databases

BioGridi4261074, 217 interactors
DIPiDIP-47852N
IntActiP0AG48, 90 interactors
STRINGi316385.ECDH10B_3360

Structurei

Secondary structure

1103
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi2 – 7Combined sources6
Beta strandi10 – 15Combined sources6
Beta strandi19 – 23Combined sources5
Beta strandi32 – 35Combined sources4
Beta strandi38 – 43Combined sources6
Beta strandi46 – 49Combined sources4
Beta strandi51 – 53Combined sources3
Beta strandi58 – 68Combined sources11
Beta strandi72 – 78Combined sources7
Turni79 – 82Combined sources4
Beta strandi83 – 89Combined sources7
Beta strandi92 – 102Combined sources11

3D structure databases

ProteinModelPortaliP0AG48
SMRiP0AG48
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0AG48

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial ribosomal protein bL21 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0261 LUCA
HOGENOMiHOG000036265
InParanoidiP0AG48
KOiK02888
OMAiGHRQQYT
PhylomeDBiP0AG48

Family and domain databases

HAMAPiMF_01363 Ribosomal_L21, 1 hit
InterProiView protein in InterPro
IPR036164 L21-like_sf
IPR028909 L21p-like
IPR001787 Ribosomal_L21
IPR018258 Ribosomal_L21_CS
PANTHERiPTHR21349 PTHR21349, 1 hit
PfamiView protein in Pfam
PF00829 Ribosomal_L21p, 1 hit
SUPFAMiSSF141091 SSF141091, 1 hit
TIGRFAMsiTIGR00061 L21, 1 hit
PROSITEiView protein in PROSITE
PS01169 RIBOSOMAL_L21, 1 hit

Sequencei

Sequence statusi: Complete.

P0AG48-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYAVFQSGGK QHRVSEGQTV RLEKLDIATG ETVEFAEVLM IANGEEVKIG
60 70 80 90 100
VPFVDGGVIK AEVVAHGRGE KVKIVKFRRR KHYRKQQGHR QWFTDVKITG

ISA
Length:103
Mass (Da):11,564
Last modified:July 21, 1986 - v1
Checksum:i9221F104EC9C8CDB
GO

Mass spectrometryi

Molecular mass is 11562.7 Da from positions 1 - 103. Determined by MALDI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D13267 Genomic DNA Translation: BAA02525.1
U18997 Genomic DNA Translation: AAA57987.1
U00096 Genomic DNA Translation: AAC76218.1
AP009048 Genomic DNA Translation: BAE77230.1
PIRiJS0766 R5EC21
RefSeqiNP_417653.1, NC_000913.3
WP_000271401.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76218; AAC76218; b3186
BAE77230; BAE77230; BAE77230
GeneIDi30329540
949057
KEGGiecj:JW3153
eco:b3186
PATRICifig|1411691.4.peg.3545

Similar proteinsi

Entry informationi

Entry nameiRL21_ECOLI
AccessioniPrimary (citable) accession number: P0AG48
Secondary accession number(s): P02422, Q2M926
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: June 20, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

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