UniProtKB - P0AFU2 (YFBS_ECOLI)
Protein
Uncharacterized transporter YfbS
Gene
yfbS
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Molecular functioni
- cation transmembrane transporter activity Source: InterPro
GO - Biological processi
- potassium ion transport Source: InterPro
Keywordsi
Biological process | Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:G7186-MONOMER |
Protein family/group databases
TCDBi | 2.A.47.4.8, the divalent anion:na(+) symporter (dass) family |
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized transporter YfbS |
Gene namesi | Name:yfbS Ordered Locus Names:b2292, JW2289 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell inner membrane Curated; Multi-pass membrane protein Curated
Plasma Membrane
- plasma membrane Source: EcoCyc
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 1 – 21 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 29 – 49 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 51 – 71 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 78 – 98 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 102 – 122 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 136 – 156 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 175 – 195 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 373 – 393 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 425 – 445 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 464 – 484 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 503 – 523 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 543 – 563 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 588 – 608 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000172503 | 1 – 610 | Uncharacterized transporter YfbSAdd BLAST | 610 |
Proteomic databases
jPOSTi | P0AFU2 |
PaxDbi | P0AFU2 |
PRIDEi | P0AFU2 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4262968, 215 interactors |
DIPi | DIP-48033N |
IntActi | P0AFU2, 1 interactor |
STRINGi | 511145.b2292 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 218 – 307 | RCK C-terminal 1PROSITE-ProRule annotationAdd BLAST | 90 | |
Domaini | 314 – 398 | RCK C-terminal 2PROSITE-ProRule annotationAdd BLAST | 85 |
Sequence similaritiesi
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG0471, Bacteria COG0490, Bacteria |
HOGENOMi | CLU_005170_6_1_6 |
InParanoidi | P0AFU2 |
PhylomeDBi | P0AFU2 |
Family and domain databases
Gene3Di | 3.30.70.1450, 2 hits |
InterProi | View protein in InterPro IPR004680, Cit_transptr-like_dom IPR031312, Na/sul_symport_CS IPR006037, RCK_C IPR036721, RCK_C_sf |
Pfami | View protein in Pfam PF03600, CitMHS, 2 hits PF02080, TrkA_C, 2 hits |
SUPFAMi | SSF116726, SSF116726, 2 hits |
PROSITEi | View protein in PROSITE PS01271, NA_SULFATE, 1 hit PS51202, RCK_C, 2 hits |
i Sequence
Sequence statusi: Complete.
P0AFU2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNGELIWVLS LLAVAIVLFA TGRVRMDAVA LFVIVAFALS GTLTVPEVFS
60 70 80 90 100
GFSDPNVVLI AALFIIGDGL VRTGVATVMG TWLVKVAGNS EIKMLVLLML
110 120 130 140 150
TVAGLGAFMS STGVVAIFIP VVLSVAMRMQ TSPSRLMMPL SFAGLISGMM
160 170 180 190 200
TLVATPPNLV VNSELLREGY HGFSFFSVTP IGLVVLVLGI LYMLVMRFML
210 220 230 240 250
KGDTQTPQRE GWTRRTFRDL IREYRLTGRA RRLAIRPGSP MIGQRLDDLK
260 270 280 290 300
LRERYGANVI GVERWRRFRR VIVNVNGVSE FRARDVLLID MSAADVDLRQ
310 320 330 340 350
FCSEQLLEPM VLRGEYFSDQ ALDVGMAEIS LIPESELIGK SVREIGFRTR
360 370 380 390 400
YGLNVVGLKR NGVALEGSLA DEPLLLGDII LVVGNWKLIG MLAKQGRDFV
410 420 430 440 450
ALNLPEEVSE ASPAHSQAPH AIFCLVLMVA LMLTDEIPNP VAAIIACLLM
460 470 480 490 500
GKFRCIDAES AYKSIHWPSI ILIVGMMPFA VALQKTGGVA LAVKGLMDIG
510 520 530 540 550
GGYGPHMMLG CLFVLSAVIG LFISNTATAV LMAPIALAAA KTMGVSPYPF
560 570 580 590 600
AMVVAMAASA AFMTPVSSPV NTLVLGPGNY SFSDFVKLGV PFTIIVMAVC
610
VVMIPMLFPF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC75352.1 AP009048 Genomic DNA Translation: BAA16128.1 |
PIRi | B65001 |
RefSeqi | NP_416795.1, NC_000913.3 WP_001012899.1, NZ_STEB01000008.1 |
Genome annotation databases
EnsemblBacteriai | AAC75352; AAC75352; b2292 BAA16128; BAA16128; BAA16128 |
GeneIDi | 58462917 946766 |
KEGGi | ecj:JW2289 eco:b2292 |
PATRICi | fig|1411691.4.peg.4443 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC75352.1 AP009048 Genomic DNA Translation: BAA16128.1 |
PIRi | B65001 |
RefSeqi | NP_416795.1, NC_000913.3 WP_001012899.1, NZ_STEB01000008.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4262968, 215 interactors |
DIPi | DIP-48033N |
IntActi | P0AFU2, 1 interactor |
STRINGi | 511145.b2292 |
Protein family/group databases
TCDBi | 2.A.47.4.8, the divalent anion:na(+) symporter (dass) family |
Proteomic databases
jPOSTi | P0AFU2 |
PaxDbi | P0AFU2 |
PRIDEi | P0AFU2 |
Genome annotation databases
EnsemblBacteriai | AAC75352; AAC75352; b2292 BAA16128; BAA16128; BAA16128 |
GeneIDi | 58462917 946766 |
KEGGi | ecj:JW2289 eco:b2292 |
PATRICi | fig|1411691.4.peg.4443 |
Organism-specific databases
EchoBASEi | EB3856 |
Phylogenomic databases
eggNOGi | COG0471, Bacteria COG0490, Bacteria |
HOGENOMi | CLU_005170_6_1_6 |
InParanoidi | P0AFU2 |
PhylomeDBi | P0AFU2 |
Enzyme and pathway databases
BioCyci | EcoCyc:G7186-MONOMER |
Miscellaneous databases
PROi | PR:P0AFU2 |
Family and domain databases
Gene3Di | 3.30.70.1450, 2 hits |
InterProi | View protein in InterPro IPR004680, Cit_transptr-like_dom IPR031312, Na/sul_symport_CS IPR006037, RCK_C IPR036721, RCK_C_sf |
Pfami | View protein in Pfam PF03600, CitMHS, 2 hits PF02080, TrkA_C, 2 hits |
SUPFAMi | SSF116726, SSF116726, 2 hits |
PROSITEi | View protein in PROSITE PS01271, NA_SULFATE, 1 hit PS51202, RCK_C, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YFBS_ECOLI | |
Accessioni | P0AFU2Primary (citable) accession number: P0AFU2 Secondary accession number(s): P76935, P77741 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 20, 2005 |
Last sequence update: | December 20, 2005 | |
Last modified: | April 7, 2021 | |
This is version 111 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families