UniProtKB - P0AFH2 (OPPB_ECOLI)
Protein
Oligopeptide transport system permease protein OppB
Gene
oppB
Organism
Escherichia coli (strain K12)
Status
Functioni
Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane.
GO - Biological processi
- protein transport Source: UniProtKB-KW
- transmembrane transport Source: InterPro
Keywordsi
Biological process | Peptide transport, Protein transport, Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:OPPB-MONOMER MetaCyc:OPPB-MONOMER |
Protein family/group databases
TCDBi | 3.A.1.5.41, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Oligopeptide transport system permease protein OppB |
Gene namesi | Name:oppB Ordered Locus Names:b1244, JW1236 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
Plasma Membrane
- plasma membrane Source: EcoCyc
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 9 | Cytoplasmic1 Publication | 9 | |
Transmembranei | 10 – 30 | HelicalCuratedAdd BLAST | 21 | |
Topological domaini | 31 – 99 | Extracellular1 PublicationAdd BLAST | 69 | |
Transmembranei | 100 – 121 | HelicalCuratedAdd BLAST | 22 | |
Topological domaini | 122 – 137 | Cytoplasmic1 PublicationAdd BLAST | 16 | |
Transmembranei | 138 – 158 | HelicalCuratedAdd BLAST | 21 | |
Topological domaini | 159 – 172 | Extracellular1 PublicationAdd BLAST | 14 | |
Transmembranei | 173 – 190 | HelicalCuratedAdd BLAST | 18 | |
Topological domaini | 191 – 226 | Cytoplasmic1 PublicationAdd BLAST | 36 | |
Transmembranei | 227 – 250 | HelicalCuratedAdd BLAST | 24 | |
Topological domaini | 251 – 271 | Extracellular1 PublicationAdd BLAST | 21 | |
Transmembranei | 272 – 293 | HelicalCuratedAdd BLAST | 22 | |
Topological domaini | 294 – 306 | Cytoplasmic1 PublicationAdd BLAST | 13 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000060143 | 1 – 306 | Oligopeptide transport system permease protein OppBAdd BLAST | 306 |
Proteomic databases
jPOSTi | P0AFH2 |
PaxDbi | P0AFH2 |
PRIDEi | P0AFH2 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4261152, 281 interactors |
ComplexPortali | CPX-4343, Murein tripeptide ABC transporter complex CPX-4344, Oligopeptide ABC transporter complex |
DIPi | DIP-48074N |
STRINGi | 511145.b1244 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 94 – 293 | ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST | 200 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG0601, Bacteria |
InParanoidi | P0AFH2 |
PhylomeDBi | P0AFH2 |
Family and domain databases
CDDi | cd06261, TM_PBP2, 1 hit |
Gene3Di | 1.10.3720.10, 1 hit |
InterProi | View protein in InterPro IPR000515, MetI-like IPR035906, MetI-like_sf |
Pfami | View protein in Pfam PF00528, BPD_transp_1, 1 hit |
SUPFAMi | SSF161098, SSF161098, 1 hit |
PROSITEi | View protein in PROSITE PS50928, ABC_TM1, 1 hit |
i Sequence
Sequence statusi: Complete.
P0AFH2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLKFILRRCL EAIPTLFILI TISFFMMRLA PGSPFTGERT LPPEVMANIE
60 70 80 90 100
AKYHLNDPIM TQYFSYLKQL AHGDFGPSFK YKDYSVNDLV ASSFPVSAKL
110 120 130 140 150
GAAAFFLAVI LGVSAGVIAA LKQNTKWDYT VMGLAMTGVV IPSFVVAPLL
160 170 180 190 200
VMIFAIILHW LPGGGWNGGA LKFMILPMVA LSLAYIASIA RITRGSMIEV
210 220 230 240 250
LHSNFIRTAR AKGLPMRRII LRHALKPALL PVLSYMGPAF VGIITGSMVI
260 270 280 290 300
ETIYGLPGIG QLFVNGALNR DYSLVLSLTI LVGALTILFN AIVDVLYAVI
DPKIRY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74326.1 AP009048 Genomic DNA Translation: BAA14776.1 J05433 Genomic DNA No translation available. |
PIRi | G64871, B36263 |
RefSeqi | NP_415760.1, NC_000913.3 WP_000911112.1, NZ_STEB01000005.1 |
Genome annotation databases
EnsemblBacteriai | AAC74326; AAC74326; b1244 BAA14776; BAA14776; BAA14776 |
GeneIDi | 58463013 945823 |
KEGGi | ecj:JW1236 eco:b1244 |
PATRICi | fig|1411691.4.peg.1039 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74326.1 AP009048 Genomic DNA Translation: BAA14776.1 J05433 Genomic DNA No translation available. |
PIRi | G64871, B36263 |
RefSeqi | NP_415760.1, NC_000913.3 WP_000911112.1, NZ_STEB01000005.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4261152, 281 interactors |
ComplexPortali | CPX-4343, Murein tripeptide ABC transporter complex CPX-4344, Oligopeptide ABC transporter complex |
DIPi | DIP-48074N |
STRINGi | 511145.b1244 |
Protein family/group databases
TCDBi | 3.A.1.5.41, the atp-binding cassette (abc) superfamily |
Proteomic databases
jPOSTi | P0AFH2 |
PaxDbi | P0AFH2 |
PRIDEi | P0AFH2 |
Genome annotation databases
EnsemblBacteriai | AAC74326; AAC74326; b1244 BAA14776; BAA14776; BAA14776 |
GeneIDi | 58463013 945823 |
KEGGi | ecj:JW1236 eco:b1244 |
PATRICi | fig|1411691.4.peg.1039 |
Organism-specific databases
EchoBASEi | EB0669 |
Phylogenomic databases
eggNOGi | COG0601, Bacteria |
InParanoidi | P0AFH2 |
PhylomeDBi | P0AFH2 |
Enzyme and pathway databases
BioCyci | EcoCyc:OPPB-MONOMER MetaCyc:OPPB-MONOMER |
Miscellaneous databases
PROi | PR:P0AFH2 |
Family and domain databases
CDDi | cd06261, TM_PBP2, 1 hit |
Gene3Di | 1.10.3720.10, 1 hit |
InterProi | View protein in InterPro IPR000515, MetI-like IPR035906, MetI-like_sf |
Pfami | View protein in Pfam PF00528, BPD_transp_1, 1 hit |
SUPFAMi | SSF161098, SSF161098, 1 hit |
PROSITEi | View protein in PROSITE PS50928, ABC_TM1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | OPPB_ECOLI | |
Accessioni | P0AFH2Primary (citable) accession number: P0AFH2 Secondary accession number(s): P31132, P76026, P77550 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 20, 2005 |
Last sequence update: | December 20, 2005 | |
Last modified: | February 10, 2021 | |
This is version 104 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families