UniProtKB - P0AF96 (TABA_ECOLI)
Protein
Toxin-antitoxin biofilm protein TabA
Gene
tabA
Organism
Escherichia coli (strain K12)
Status
Functioni
Influences biofilm formation. Represses fimbria genes in 8 hours biofilms. May act in response to the combined activity of several toxin-antitoxin (TA) systems.1 Publication
GO - Biological processi
- single-species biofilm formation Source: EcoCyc
Enzyme and pathway databases
BioCyci | EcoCyc:G7883-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Toxin-antitoxin biofilm protein TabA |
Gene namesi | Name:tabA Synonyms:yjgK Ordered Locus Names:b4252, JW5756 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Pathology & Biotechi
Disruption phenotypei
Deletion increases biofilm formation after 8 hours and decreases biofilm formation after 24 hours.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000169765 | 1 – 150 | Toxin-antitoxin biofilm protein TabAAdd BLAST | 150 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 36 | N6-acetyllysine1 Publication | 1 |
Keywords - PTMi
AcetylationProteomic databases
jPOSTi | P0AF96 |
PaxDbi | P0AF96 |
PRIDEi | P0AF96 |
PTM databases
iPTMneti | P0AF96 |
Expressioni
Inductioni
Induced by simultaneous deletion of five TA systems (MazF/MazE, RelE/RelB, ChpB, YoeB/YefM, and YafQ/DinJ).1 Publication
Interactioni
Protein-protein interaction databases
BioGRIDi | 4259562, 211 interactors |
DIPi | DIP-48214N |
STRINGi | 511145.b4252 |
Family & Domainsi
Sequence similaritiesi
Belongs to the TabA/YhcH/YiaL family.Curated
Phylogenomic databases
eggNOGi | COG2731, Bacteria |
HOGENOMi | CLU_107139_3_0_6 |
InParanoidi | P0AF96 |
PhylomeDBi | P0AF96 |
Family and domain databases
Gene3Di | 2.60.120.370, 1 hit |
InterProi | View protein in InterPro IPR004375, YhcH/YjgK/YiaL IPR037012, YhcH/YjgK/YiaL_sf |
PANTHERi | PTHR34986, PTHR34986, 1 hit |
Pfami | View protein in Pfam PF04074, DUF386, 1 hit |
TIGRFAMsi | TIGR00022, TIGR00022, 1 hit |
i Sequence
Sequence statusi: Complete.
P0AF96-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIIGNIHNLQ PWLPQELRQA IEHIKAHVTA ETPKGKHDIE GNRLFYLISE
60 70 80 90 100
DMTEPYEARR AEYHARYLDI QIVLKGQEGM TFSTQPAGAP DTDWLADKDI
110 120 130 140 150
AFLPEGVDEK TVILNEGDFV VFYPGEVHKP LCAVGAPAQV RKAVVKMLMA
Sequence cautioni
The sequence AAA97148 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U14003 Genomic DNA Translation: AAA97148.1 Different initiation. U00096 Genomic DNA Translation: AAC77209.2 AP009048 Genomic DNA Translation: BAE78249.1 |
PIRi | S56477 |
RefSeqi | NP_418673.4, NC_000913.3 WP_000583469.1, NZ_LN832404.1 |
Genome annotation databases
EnsemblBacteriai | AAC77209; AAC77209; b4252 BAE78249; BAE78249; BAE78249 |
GeneIDi | 58390508 948777 |
KEGGi | ecj:JW5756 eco:b4252 |
PATRICi | fig|1411691.4.peg.2452 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U14003 Genomic DNA Translation: AAA97148.1 Different initiation. U00096 Genomic DNA Translation: AAC77209.2 AP009048 Genomic DNA Translation: BAE78249.1 |
PIRi | S56477 |
RefSeqi | NP_418673.4, NC_000913.3 WP_000583469.1, NZ_LN832404.1 |
3D structure databases
SMRi | P0AF96 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4259562, 211 interactors |
DIPi | DIP-48214N |
STRINGi | 511145.b4252 |
PTM databases
iPTMneti | P0AF96 |
Proteomic databases
jPOSTi | P0AF96 |
PaxDbi | P0AF96 |
PRIDEi | P0AF96 |
Genome annotation databases
EnsemblBacteriai | AAC77209; AAC77209; b4252 BAE78249; BAE78249; BAE78249 |
GeneIDi | 58390508 948777 |
KEGGi | ecj:JW5756 eco:b4252 |
PATRICi | fig|1411691.4.peg.2452 |
Organism-specific databases
EchoBASEi | EB2420 |
Phylogenomic databases
eggNOGi | COG2731, Bacteria |
HOGENOMi | CLU_107139_3_0_6 |
InParanoidi | P0AF96 |
PhylomeDBi | P0AF96 |
Enzyme and pathway databases
BioCyci | EcoCyc:G7883-MONOMER |
Miscellaneous databases
PROi | PR:P0AF96 |
Family and domain databases
Gene3Di | 2.60.120.370, 1 hit |
InterProi | View protein in InterPro IPR004375, YhcH/YjgK/YiaL IPR037012, YhcH/YjgK/YiaL_sf |
PANTHERi | PTHR34986, PTHR34986, 1 hit |
Pfami | View protein in Pfam PF04074, DUF386, 1 hit |
TIGRFAMsi | TIGR00022, TIGR00022, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TABA_ECOLI | |
Accessioni | P0AF96Primary (citable) accession number: P0AF96 Secondary accession number(s): P39335, Q2M657 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 20, 2005 |
Last sequence update: | December 20, 2005 | |
Last modified: | February 10, 2021 | |
This is version 102 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families