UniProtKB - P0AF01 (MODB_ECOLI)
Protein
Molybdenum transport system permease protein ModB
Gene
modB
Organism
Escherichia coli (strain K12)
Status
Functioni
Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.
GO - Molecular functioni
- molybdate ion transmembrane transporter activity Source: InterPro
Keywordsi
Biological process | Transport |
Ligand | Molybdenum |
Enzyme and pathway databases
BioCyci | EcoCyc:MODB-MONOMER MetaCyc:MODB-MONOMER |
Protein family/group databases
TCDBi | 3.A.1.8.1, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Molybdenum transport system permease protein ModB |
Gene namesi | Name:modB Synonyms:chlJ Ordered Locus Names:b0764, JW0747 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
Plasma Membrane
- integral component of plasma membrane Source: EcoCyc
- plasma membrane Source: EcoCyc
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 16 | PeriplasmicSequence analysisAdd BLAST | 16 | |
Transmembranei | 17 – 37 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 38 – 49 | CytoplasmicSequence analysisAdd BLAST | 12 | |
Transmembranei | 50 – 70 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 71 – 83 | PeriplasmicSequence analysisAdd BLAST | 13 | |
Transmembranei | 84 – 104 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 105 – 136 | CytoplasmicSequence analysisAdd BLAST | 32 | |
Transmembranei | 137 – 157 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 158 – 201 | PeriplasmicSequence analysisAdd BLAST | 44 | |
Transmembranei | 202 – 222 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 223 – 229 | CytoplasmicSequence analysis | 7 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000060111 | 1 – 229 | Molybdenum transport system permease protein ModBAdd BLAST | 229 |
Proteomic databases
PaxDbi | P0AF01 |
PRIDEi | P0AF01 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4261270, 8 interactors |
ComplexPortali | CPX-4342, Molybdate ABC transporter complex |
IntActi | P0AF01, 4 interactors |
STRINGi | 511145.b0764 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 11 – 219 | ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST | 209 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG4149, Bacteria |
HOGENOMi | CLU_016047_14_3_6 |
InParanoidi | P0AF01 |
PhylomeDBi | P0AF01 |
Family and domain databases
CDDi | cd06261, TM_PBP2, 1 hit |
Gene3Di | 1.10.3720.10, 1 hit |
InterProi | View protein in InterPro IPR000515, MetI-like IPR035906, MetI-like_sf IPR011867, ModB_ABC |
Pfami | View protein in Pfam PF00528, BPD_transp_1, 1 hit |
SUPFAMi | SSF161098, SSF161098, 1 hit |
TIGRFAMsi | TIGR02141, modB_ABC, 1 hit |
PROSITEi | View protein in PROSITE PS50928, ABC_TM1, 1 hit |
i Sequence
Sequence statusi: Complete.
P0AF01-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MILTDPEWQA VLLSLKVSSL AVLFSLPFGI FFAWLLVRCT FPGKALLDSV
60 70 80 90 100
LHLPLVLPPV VVGYLLLVSM GRRGFIGERL YDWFGITFAF SWRGAVLAAA
110 120 130 140 150
VMSFPLMVRA IRLALEGVDV KLEQAARTLG AGRWRVFFTI TLPLTLPGII
160 170 180 190 200
VGTVLAFARS LGEFGATITF VSNIPGETRT IPSAMYTLIQ TPGGESGAAR
210 220
LCIISIALAM ISLLISEWLA RISRERAGR
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 40 | T → S (PubMed:7665460).Curated | 1 | |
Sequence conflicti | 40 | T → S (PubMed:8564363).Curated | 1 | |
Sequence conflicti | 40 | T → S (PubMed:3553151).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L34009 Genomic DNA Translation: AAB00836.1 U27192 Genomic DNA Translation: AAB60172.1 U07867 Genomic DNA Translation: AAB06894.1 U00096 Genomic DNA Translation: AAC73851.1 AP009048 Genomic DNA Translation: BAA35428.1 M16182 Genomic DNA Translation: AAA83839.1 |
PIRi | D64812, BVECHJ |
RefSeqi | NP_415285.1, NC_000913.3 WP_000604034.1, NZ_STEB01000028.1 |
Genome annotation databases
EnsemblBacteriai | AAC73851; AAC73851; b0764 BAA35428; BAA35428; BAA35428 |
GeneIDi | 58460867 945361 |
KEGGi | ecj:JW0747 eco:b0764 |
PATRICi | fig|1411691.4.peg.1514 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L34009 Genomic DNA Translation: AAB00836.1 U27192 Genomic DNA Translation: AAB60172.1 U07867 Genomic DNA Translation: AAB06894.1 U00096 Genomic DNA Translation: AAC73851.1 AP009048 Genomic DNA Translation: BAA35428.1 M16182 Genomic DNA Translation: AAA83839.1 |
PIRi | D64812, BVECHJ |
RefSeqi | NP_415285.1, NC_000913.3 WP_000604034.1, NZ_STEB01000028.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4261270, 8 interactors |
ComplexPortali | CPX-4342, Molybdate ABC transporter complex |
IntActi | P0AF01, 4 interactors |
STRINGi | 511145.b0764 |
Protein family/group databases
TCDBi | 3.A.1.8.1, the atp-binding cassette (abc) superfamily |
Proteomic databases
PaxDbi | P0AF01 |
PRIDEi | P0AF01 |
Genome annotation databases
EnsemblBacteriai | AAC73851; AAC73851; b0764 BAA35428; BAA35428; BAA35428 |
GeneIDi | 58460867 945361 |
KEGGi | ecj:JW0747 eco:b0764 |
PATRICi | fig|1411691.4.peg.1514 |
Organism-specific databases
EchoBASEi | EB0002 |
Phylogenomic databases
eggNOGi | COG4149, Bacteria |
HOGENOMi | CLU_016047_14_3_6 |
InParanoidi | P0AF01 |
PhylomeDBi | P0AF01 |
Enzyme and pathway databases
BioCyci | EcoCyc:MODB-MONOMER MetaCyc:MODB-MONOMER |
Miscellaneous databases
PROi | PR:P0AF01 |
Family and domain databases
CDDi | cd06261, TM_PBP2, 1 hit |
Gene3Di | 1.10.3720.10, 1 hit |
InterProi | View protein in InterPro IPR000515, MetI-like IPR035906, MetI-like_sf IPR011867, ModB_ABC |
Pfami | View protein in Pfam PF00528, BPD_transp_1, 1 hit |
SUPFAMi | SSF161098, SSF161098, 1 hit |
TIGRFAMsi | TIGR02141, modB_ABC, 1 hit |
PROSITEi | View protein in PROSITE PS50928, ABC_TM1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | MODB_ECOLI | |
Accessioni | P0AF01Primary (citable) accession number: P0AF01 Secondary accession number(s): P09834, P77537 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 20, 2005 |
Last sequence update: | December 20, 2005 | |
Last modified: | February 10, 2021 | |
This is version 111 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families