UniProtKB - P0AET5 (HDED_ECOLI)
Protein
Protein HdeD
Gene
hdeD
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Biological processi
- response to pH Source: EcoCyc
Enzyme and pathway databases
BioCyci | EcoCyc:EG11495-MONOMER |
Protein family/group databases
TCDBi | 9.B.36.1.1, the acid resistance membrane protein (hded) family |
Names & Taxonomyi
Protein namesi | Recommended name: Protein HdeD |
Gene namesi | Name:hdeD Synonyms:yhiA Ordered Locus Names:b3511, JW3479 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 25 | CytoplasmicSequence analysisAdd BLAST | 25 | |
Transmembranei | 26 – 44 | HelicalSequence analysisAdd BLAST | 19 | |
Topological domaini | 45 – 47 | PeriplasmicSequence analysis | 3 | |
Transmembranei | 48 – 70 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 71 – 76 | CytoplasmicSequence analysis | 6 | |
Transmembranei | 77 – 99 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 100 – 103 | PeriplasmicSequence analysis | 4 | |
Transmembranei | 104 – 126 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 127 – 138 | CytoplasmicSequence analysisAdd BLAST | 12 | |
Transmembranei | 139 – 161 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 162 – 164 | PeriplasmicSequence analysis | 3 | |
Transmembranei | 165 – 187 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 188 – 190 | CytoplasmicSequence analysis | 3 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: EcoCyc
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000083935 | 1 – 190 | Protein HdeDAdd BLAST | 190 |
Proteomic databases
jPOSTi | P0AET5 |
PaxDbi | P0AET5 |
PRIDEi | P0AET5 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4259561, 5 interactors |
DIPi | DIP-48170N |
IntActi | P0AET5, 1 interactor |
STRINGi | 511145.b3511 |
Family & Domainsi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG3247, Bacteria |
HOGENOMi | CLU_091585_6_0_6 |
InParanoidi | P0AET5 |
Family and domain databases
InterProi | View protein in InterPro IPR005325, DUF308_memb |
Pfami | View protein in Pfam PF03729, DUF308, 2 hits |
i Sequence
Sequence statusi: Complete.
P0AET5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLYIDKATIL KFDLEMLKKH RRAIQFIAVL LFIVGLLCIS FPFVSGDILS
60 70 80 90 100
TVVGALLICS GIALIVGLFS NRSHNFWPVL SGFLVAVAYL LIGYFFIRAP
110 120 130 140 150
ELGIFAIAAF IAGLFCVAGV IRLMSWYRQR SMKGSWLQLV IGVLDIVIAW
160 170 180 190
IFLGATPMVS VTLVSTLVGI ELIFSAASLF SFASLFVKQQ
Sequence cautioni
The sequence BAA01882 differs from that shown. Reason: Erroneous initiation.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D11389 Genomic DNA Translation: BAA01985.1 U00039 Genomic DNA Translation: AAB18487.1 U00096 Genomic DNA Translation: AAC76536.1 AP009048 Genomic DNA Translation: BAE77783.1 D11109 Genomic DNA Translation: BAA01882.1 Different initiation. |
PIRi | S47731 |
RefSeqi | NP_417968.1, NC_000913.3 WP_000965672.1, NZ_STEB01000046.1 |
Genome annotation databases
EnsemblBacteriai | AAC76536; AAC76536; b3511 BAE77783; BAE77783; BAE77783 |
GeneIDi | 58463705 948024 |
KEGGi | ecj:JW3479 eco:b3511 |
PATRICi | fig|1411691.4.peg.3208 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D11389 Genomic DNA Translation: BAA01985.1 U00039 Genomic DNA Translation: AAB18487.1 U00096 Genomic DNA Translation: AAC76536.1 AP009048 Genomic DNA Translation: BAE77783.1 D11109 Genomic DNA Translation: BAA01882.1 Different initiation. |
PIRi | S47731 |
RefSeqi | NP_417968.1, NC_000913.3 WP_000965672.1, NZ_STEB01000046.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4259561, 5 interactors |
DIPi | DIP-48170N |
IntActi | P0AET5, 1 interactor |
STRINGi | 511145.b3511 |
Protein family/group databases
TCDBi | 9.B.36.1.1, the acid resistance membrane protein (hded) family |
Proteomic databases
jPOSTi | P0AET5 |
PaxDbi | P0AET5 |
PRIDEi | P0AET5 |
Genome annotation databases
EnsemblBacteriai | AAC76536; AAC76536; b3511 BAE77783; BAE77783; BAE77783 |
GeneIDi | 58463705 948024 |
KEGGi | ecj:JW3479 eco:b3511 |
PATRICi | fig|1411691.4.peg.3208 |
Organism-specific databases
EchoBASEi | EB1458 |
Phylogenomic databases
eggNOGi | COG3247, Bacteria |
HOGENOMi | CLU_091585_6_0_6 |
InParanoidi | P0AET5 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11495-MONOMER |
Miscellaneous databases
PROi | PR:P0AET5 |
Family and domain databases
InterProi | View protein in InterPro IPR005325, DUF308_memb |
Pfami | View protein in Pfam PF03729, DUF308, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | HDED_ECOLI | |
Accessioni | P0AET5Primary (citable) accession number: P0AET5 Secondary accession number(s): P26603, P28326, Q2M7H3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 20, 2005 |
Last sequence update: | December 20, 2005 | |
Last modified: | February 10, 2021 | |
This is version 102 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |