UniProtKB - P0AEG1 (DPPC_ECOLI)
Protein
Dipeptide transport system permease protein DppC
Gene
dppC
Organism
Escherichia coli (strain K12)
Status
Functioni
Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane.
GO - Molecular functioni
- dipeptide transmembrane transporter activity Source: GO_Central
GO - Biological processi
- protein transport Source: UniProtKB-KW
Keywordsi
Biological process | Peptide transport, Protein transport, Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:DPPC-MONOMER MetaCyc:DPPC-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Dipeptide transport system permease protein DppC |
Gene namesi | Name:dppC Ordered Locus Names:b3542, JW3511 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 31 | CytoplasmicSequence analysisAdd BLAST | 31 | |
Transmembranei | 32 – 52 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 53 – 101 | PeriplasmicSequence analysisAdd BLAST | 49 | |
Transmembranei | 102 – 122 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 123 – 136 | CytoplasmicSequence analysisAdd BLAST | 14 | |
Transmembranei | 137 – 157 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 158 – 206 | PeriplasmicSequence analysisAdd BLAST | 49 | |
Transmembranei | 207 – 227 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 228 – 230 | CytoplasmicSequence analysis | 3 | |
Transmembranei | 231 – 251 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 252 – 265 | PeriplasmicSequence analysisAdd BLAST | 14 | |
Transmembranei | 266 – 286 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Topological domaini | 287 – 300 | CytoplasmicSequence analysisAdd BLAST | 14 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: EcoCyc
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000060009 | 1 – 300 | Dipeptide transport system permease protein DppCAdd BLAST | 300 |
Proteomic databases
jPOSTi | P0AEG1 |
PaxDbi | P0AEG1 |
PRIDEi | P0AEG1 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4262184, 334 interactors |
ComplexPortali | CPX-4345, Heme/dipeptide ABC transporter complex, dppA variant CPX-4346, Heme/dipeptide ABC transporter complex, mppA variant |
DIPi | DIP-9469N |
IntActi | P0AEG1, 2 interactors |
STRINGi | 511145.b3542 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 98 – 287 | ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST | 190 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG1173, Bacteria |
HOGENOMi | CLU_028518_1_1_6 |
InParanoidi | P0AEG1 |
PhylomeDBi | P0AEG1 |
Family and domain databases
CDDi | cd06261, TM_PBP2, 1 hit |
Gene3Di | 1.10.3720.10, 1 hit |
InterProi | View protein in InterPro IPR000515, MetI-like IPR035906, MetI-like_sf IPR025966, OppC_N |
Pfami | View protein in Pfam PF00528, BPD_transp_1, 1 hit PF12911, OppC_N, 1 hit |
SUPFAMi | SSF161098, SSF161098, 1 hit |
PROSITEi | View protein in PROSITE PS50928, ABC_TM1, 1 hit |
i Sequence
Sequence statusi: Complete.
P0AEG1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSQVTENKVI SAPVPMTPLQ EFWHYFKRNK GAVVGLVYVV IVLFIAIFAN
60 70 80 90 100
WIAPYNPAEQ FRDALLAPPA WQEGGSMAHL LGTDDVGRDV LSRLMYGARL
110 120 130 140 150
SLLVGCLVVV LSLIMGVILG LIAGYFGGLV DNIIMRVVDI MLALPSLLLA
160 170 180 190 200
LVLVAIFGPS IGNAALALTF VALPHYVRLT RAAVLVEVNR DYVTASRVAG
210 220 230 240 250
AGAMRQMFIN IFPNCLAPLI VQASLGFSNA ILDMAALGFL GMGAQPPTPE
260 270 280 290 300
WGTMLSDVLQ FAQSAWWVVT FPGLAILLTV LAFNLMGDGL RDALDPKLKQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L08399 Genomic DNA Translation: AAA23704.1 U00039 Genomic DNA Translation: AAB18520.1 U00096 Genomic DNA Translation: AAC76567.1 AP009048 Genomic DNA Translation: BAE77752.1 |
PIRi | S47764 |
RefSeqi | NP_417999.1, NC_000913.3 WP_000084677.1, NZ_STEB01000018.1 |
Genome annotation databases
EnsemblBacteriai | AAC76567; AAC76567; b3542 BAE77752; BAE77752; BAE77752 |
GeneIDi | 49582481 948064 |
KEGGi | ecj:JW3511 eco:b3542 |
PATRICi | fig|1411691.4.peg.3173 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L08399 Genomic DNA Translation: AAA23704.1 U00039 Genomic DNA Translation: AAB18520.1 U00096 Genomic DNA Translation: AAC76567.1 AP009048 Genomic DNA Translation: BAE77752.1 |
PIRi | S47764 |
RefSeqi | NP_417999.1, NC_000913.3 WP_000084677.1, NZ_STEB01000018.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4262184, 334 interactors |
ComplexPortali | CPX-4345, Heme/dipeptide ABC transporter complex, dppA variant CPX-4346, Heme/dipeptide ABC transporter complex, mppA variant |
DIPi | DIP-9469N |
IntActi | P0AEG1, 2 interactors |
STRINGi | 511145.b3542 |
Proteomic databases
jPOSTi | P0AEG1 |
PaxDbi | P0AEG1 |
PRIDEi | P0AEG1 |
Genome annotation databases
EnsemblBacteriai | AAC76567; AAC76567; b3542 BAE77752; BAE77752; BAE77752 |
GeneIDi | 49582481 948064 |
KEGGi | ecj:JW3511 eco:b3542 |
PATRICi | fig|1411691.4.peg.3173 |
Organism-specific databases
EchoBASEi | EB2510 |
Phylogenomic databases
eggNOGi | COG1173, Bacteria |
HOGENOMi | CLU_028518_1_1_6 |
InParanoidi | P0AEG1 |
PhylomeDBi | P0AEG1 |
Enzyme and pathway databases
BioCyci | EcoCyc:DPPC-MONOMER MetaCyc:DPPC-MONOMER |
Miscellaneous databases
PROi | PR:P0AEG1 |
Family and domain databases
CDDi | cd06261, TM_PBP2, 1 hit |
Gene3Di | 1.10.3720.10, 1 hit |
InterProi | View protein in InterPro IPR000515, MetI-like IPR035906, MetI-like_sf IPR025966, OppC_N |
Pfami | View protein in Pfam PF00528, BPD_transp_1, 1 hit PF12911, OppC_N, 1 hit |
SUPFAMi | SSF161098, SSF161098, 1 hit |
PROSITEi | View protein in PROSITE PS50928, ABC_TM1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DPPC_ECOLI | |
Accessioni | P0AEG1Primary (citable) accession number: P0AEG1 Secondary accession number(s): P37315, Q2M7K4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 6, 2005 |
Last sequence update: | December 6, 2005 | |
Last modified: | December 2, 2020 | |
This is version 109 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families