UniProtKB - P0AEC0 (YOAE_ECOLI)
Protein
UPF0053 inner membrane protein YoaE
Gene
yoaE
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Molecular functioni
- flavin adenine dinucleotide binding Source: InterPro
Enzyme and pathway databases
BioCyci | EcoCyc:G6997-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: UPF0053 inner membrane protein YoaE |
Gene namesi | Name:yoaE Ordered Locus Names:b1816, JW1805 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 13 | CytoplasmicSequence analysisAdd BLAST | 13 | |
Transmembranei | 14 – 34 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 35 – 48 | PeriplasmicSequence analysisAdd BLAST | 14 | |
Transmembranei | 49 – 69 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 70 – 78 | CytoplasmicSequence analysis | 9 | |
Transmembranei | 79 – 99 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 100 – 124 | PeriplasmicSequence analysisAdd BLAST | 25 | |
Transmembranei | 125 – 145 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 146 – 149 | CytoplasmicSequence analysis | 4 | |
Transmembranei | 150 – 170 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 171 – 184 | PeriplasmicSequence analysisAdd BLAST | 14 | |
Transmembranei | 185 – 205 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 206 | CytoplasmicSequence analysis | 1 | |
Transmembranei | 207 – 227 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 228 – 354 | PeriplasmicSequence analysisAdd BLAST | 127 | |
Transmembranei | 355 – 375 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 376 – 518 | CytoplasmicSequence analysisAdd BLAST | 143 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: GO_Central
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000088359 | 1 – 518 | UPF0053 inner membrane protein YoaEAdd BLAST | 518 |
Proteomic databases
jPOSTi | P0AEC0 |
PaxDbi | P0AEC0 |
PRIDEi | P0AEC0 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260347, 14 interactors 850692, 1 interactor |
IntActi | P0AEC0, 1 interactor |
STRINGi | 511145.b1816 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 304 – 363 | CBS 1PROSITE-ProRule annotationAdd BLAST | 60 | |
Domaini | 367 – 427 | CBS 2PROSITE-ProRule annotationAdd BLAST | 61 |
Sequence similaritiesi
Belongs to the UPF0053 family.Curated
Keywords - Domaini
CBS domain, Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG1253, Bacteria |
HOGENOMi | CLU_015237_0_0_6 |
InParanoidi | P0AEC0 |
PhylomeDBi | P0AEC0 |
Family and domain databases
Gene3Di | 3.30.465.10, 1 hit |
InterProi | View protein in InterPro IPR000644, CBS_dom IPR036318, FAD-bd_PCMH-like_sf IPR016169, FAD-bd_PCMH_sub2 IPR005496, Integral_membrane_TerC IPR005170, Transptr-assoc_dom |
Pfami | View protein in Pfam PF03471, CorC_HlyC, 1 hit PF03741, TerC, 1 hit |
SMARTi | View protein in SMART SM01091, CorC_HlyC, 1 hit |
SUPFAMi | SSF56176, SSF56176, 1 hit |
PROSITEi | View protein in PROSITE PS51371, CBS, 2 hits |
i Sequence
Sequence statusi: Complete.
P0AEC0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEFLMDPSIW AGLLTLVVLE IVLGIDNLVF IAILADKLPP KQRDKARLLG
60 70 80 90 100
LSLALIMRLG LLSLISWMVT LTKPLFTVMD FSFSGRDLIM LFGGIFLLFK
110 120 130 140 150
ATTELHERLE NRDHDSGHGK GYASFWVVVT QIVILDAVFS LDAVITAVGM
160 170 180 190 200
VNHLPVMMAA VVIAMAVMLL ASKPLTRFVN QHPTVVVLCL SFLLMIGLSL
210 220 230 240 250
VAEGFGFHIP KGYLYAAIGF SIIIEVFNQI ARRNFIRHQS TLPLRARTAD
260 270 280 290 300
AILRLMGGKR QANVQHDADN PMPMPIPEGA FAEEERYMIN GVLTLASRSL
310 320 330 340 350
RGIMTPRGEI SWVDANLGVD EIREQLLSSP HSLFPVCRGE LDEIIGIVRA
360 370 380 390 400
KELLVALEEG VDVAAIASAS PAIIVPETLD PINLLGVLRR ARGSFVIVTN
410 420 430 440 450
EFGVVQGLVT PLDVLEAIAG EFPDADETPE IITDGDGWLV KGGTDLHALQ
460 470 480 490 500
QALDVEHLAD DDDIATVAGL VISANGHIPR VGDVIDVGPL HITIIEANDY
510
RVDLVRIVKE QPAHDEDE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74886.1 AP009048 Genomic DNA Translation: BAA15623.1 |
PIRi | H64942 |
RefSeqi | NP_416330.1, NC_000913.3 WP_000394983.1, NZ_STEB01000009.1 |
Genome annotation databases
EnsemblBacteriai | AAC74886; AAC74886; b1816 BAA15623; BAA15623; BAA15623 |
GeneIDi | 49584434 946335 |
KEGGi | ecj:JW1805 eco:b1816 |
PATRICi | fig|511145.12.peg.1893 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74886.1 AP009048 Genomic DNA Translation: BAA15623.1 |
PIRi | H64942 |
RefSeqi | NP_416330.1, NC_000913.3 WP_000394983.1, NZ_STEB01000009.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4260347, 14 interactors 850692, 1 interactor |
IntActi | P0AEC0, 1 interactor |
STRINGi | 511145.b1816 |
Proteomic databases
jPOSTi | P0AEC0 |
PaxDbi | P0AEC0 |
PRIDEi | P0AEC0 |
Genome annotation databases
EnsemblBacteriai | AAC74886; AAC74886; b1816 BAA15623; BAA15623; BAA15623 |
GeneIDi | 49584434 946335 |
KEGGi | ecj:JW1805 eco:b1816 |
PATRICi | fig|511145.12.peg.1893 |
Organism-specific databases
EchoBASEi | EB3290 |
Phylogenomic databases
eggNOGi | COG1253, Bacteria |
HOGENOMi | CLU_015237_0_0_6 |
InParanoidi | P0AEC0 |
PhylomeDBi | P0AEC0 |
Enzyme and pathway databases
BioCyci | EcoCyc:G6997-MONOMER |
Miscellaneous databases
PROi | PR:P0AEC0 |
Family and domain databases
Gene3Di | 3.30.465.10, 1 hit |
InterProi | View protein in InterPro IPR000644, CBS_dom IPR036318, FAD-bd_PCMH-like_sf IPR016169, FAD-bd_PCMH_sub2 IPR005496, Integral_membrane_TerC IPR005170, Transptr-assoc_dom |
Pfami | View protein in Pfam PF03471, CorC_HlyC, 1 hit PF03741, TerC, 1 hit |
SMARTi | View protein in SMART SM01091, CorC_HlyC, 1 hit |
SUPFAMi | SSF56176, SSF56176, 1 hit |
PROSITEi | View protein in PROSITE PS51371, CBS, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YOAE_ECOLI | |
Accessioni | P0AEC0Primary (citable) accession number: P0AEC0 Secondary accession number(s): P76262 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 6, 2005 |
Last sequence update: | December 6, 2005 | |
Last modified: | October 7, 2020 | |
This is version 109 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Uncharacterized protein families (UPF)
List of uncharacterized protein family (UPF) entries - SIMILARITY comments
Index of protein domains and families