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Protein

Translocation and assembly module subunit TamA

Gene

tamA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Part of the translocation and assembly module (TAM) autotransporter assembly complex, which functions in translocation of autotransporters across the outer membrane (PubMed:22466966, PubMed:25341963). Allows substrate (Ag43, AC P39180) to initiate penetration into the outer membrane; TamB is not necessary but may regulate this activity (PubMed:25341963). Has anion selective channel-forming ability, but the physiological relevance of this activity is unclear (PubMed:22466966).2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • protein secretion Source: EcoCyc

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Translocation, Transport

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
EcoCyc:G7874-MONOMER

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.B.33.2.4 the outer membrane protein insertion porin (bam complex) (ompip) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Translocation and assembly module subunit TamA1 Publication
Alternative name(s):
Autotransporter assembly factor TamA
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:tamA1 Publication
Synonyms:yftM, ytfM
Ordered Locus Names:b4220, JW4179
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

Escherichia coli strain K12 genome database

More...
EcoGenei
EG12513 tamA

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini22 – 264Periplasmic1 PublicationAdd BLAST243
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei265 – 276Beta stranded1 PublicationAdd BLAST12
Topological domaini277 – 278Extracellular1 Publication2
Transmembranei279 – 288Beta stranded1 Publication10
Topological domaini289 – 296Periplasmic1 Publication8
Transmembranei297 – 306Beta stranded1 Publication10
Topological domaini307 – 308Extracellular1 Publication2
Transmembranei309 – 317Beta stranded1 Publication9
Topological domaini318 – 326Periplasmic1 Publication9
Transmembranei327 – 336Beta stranded1 Publication10
Topological domaini337 – 346Extracellular1 Publication10
Transmembranei347 – 356Beta stranded1 Publication10
Topological domaini357 – 360Periplasmic1 Publication4
Transmembranei361 – 370Beta stranded1 Publication10
Topological domaini371 – 386Extracellular1 PublicationAdd BLAST16
Transmembranei387 – 395Beta stranded1 Publication9
Topological domaini396 – 405Periplasmic1 Publication10
Transmembranei406 – 415Beta stranded1 Publication10
Topological domaini416 – 427Extracellular1 PublicationAdd BLAST12
Transmembranei428 – 437Beta stranded1 Publication10
Topological domaini438 – 443Periplasmic2 Publications6
Transmembranei444 – 453Beta stranded1 Publication10
Topological domaini454 – 499Extracellular1 PublicationAdd BLAST46
Transmembranei500 – 508Beta stranded1 Publication9
Topological domaini509 – 513Periplasmic1 Publication5
Transmembranei514 – 523Beta stranded1 Publication10
Topological domaini524 – 535Extracellular1 PublicationAdd BLAST12
Transmembranei536 – 545Beta stranded1 Publication10
Topological domaini546 – 548Periplasmic1 Publication3
Transmembranei549 – 557Beta stranded1 Publication9
Topological domaini558 – 567Extracellular1 Publication10
Transmembranei568 – 577Beta stranded1 Publication10

GO - Cellular componenti

Keywords - Cellular componenti

Cell outer membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Not essential, cells grow more slowly than wild-type. No changes in permeability or outer membrane integrity. Loss of localization of an exogenous protein, P1121 (ROD_p1121 of Citrobacter rodentium), to outer membranes, loss of cell aggregation when adhesins are over-expressed in a double tamA-tamB deletion mutant.2 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 211 PublicationAdd BLAST21
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001394622 – 577Translocation and assembly module subunit TamAAdd BLAST556

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P0ADE4

PRoteomics IDEntifications database

More...
PRIDEi
P0ADE4

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with TamB to form the translocation and assembly module (TAM).3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
tamBP393212EBI-1114298,EBI-1117885

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
4259308, 280 interactors

Database of interacting proteins

More...
DIPi
DIP-51058N

Protein interaction database and analysis system

More...
IntActi
P0ADE4, 7 interactors

STRING: functional protein association networks

More...
STRINGi
316385.ECDH10B_4415

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1577
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P0ADE4

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P0ADE4

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini187 – 263POTRAPROSITE-ProRule annotationAdd BLAST77

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni22 – 106POTRA1, required for interaction with TamB1 PublicationAdd BLAST85
Regioni107 – 170POTRA21 PublicationAdd BLAST64
Regioni171 – 250POTRA31 PublicationAdd BLAST80
Regioni244 – 577Sufficient for outer membrane targetingAdd BLAST334

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Contains 3 N-terminal periplasmic polypeptide transport-associated (POTRA) domains and a C-terminal 16-stranded beta-barrel transmembrane region (PubMed:24056943, PubMed:25341963). The 3 POTRA domains seem to form a rigid body (unlike BamA where the 5 POTRA domains are able to move independently) (PubMed:26243377). Upon substrate binding (Ag43, AC P39180) the 3 POTRA domains move away from the inner surface of the outer membrane by about 30 Angstroms, which would deform either the outer membrane or TamB and may provide force to reset TAM (PubMed:25341963). POTRA1 is required for interaction with TamB (PubMed:26243377). Deletion of POTRA1 decreases Ag43 binding to this protein, whereas deletion of POTRA1 and 2 obviates binding to Ag43 (PubMed:26243377). The beta-barrel is closed on the extracellular face by loop 6 (residues 456-495), while the C-terminal beta-strand forms an inward kink which may act as a gate for substrate access from the periplasm. This kink weakens the beta-strand pair between the first and last strands which may contribute to gating and substrate translocation (PubMed:24056943).Curated3 Publications

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TamA family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105CFU Bacteria
COG0729 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000275353

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P0ADE4

KEGG Orthology (KO)

More...
KOi
K07278

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P0ADE4

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000184 Bac_surfAg_D15
IPR010827 BamA/TamA_POTRA
IPR039910 D15-like
IPR034746 POTRA
IPR035243 TamA_POTRA_Dom_1

The PANTHER Classification System

More...
PANTHERi
PTHR12815 PTHR12815, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01103 Bac_surface_Ag, 1 hit
PF07244 POTRA, 1 hit
PF17243 POTRA_TamA_1, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51779 POTRA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P0ADE4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRYIRQLCCV SLLCLSGSAV AANVRLQVEG LSGQLEKNVR AQLSTIESDE
60 70 80 90 100
VTPDRRFRAR VDDAIREGLK ALGYYQPTIE FDLRPPPKKG RQVLIAKVTP
110 120 130 140 150
GVPVLIGGTD VVLRGGARTD KDYLKLLDTR PAIGTVLNQG DYENFKKSLT
160 170 180 190 200
SIALRKGYFD SEFTKAQLGI ALGLHKAFWD IDYNSGERYR FGHVTFEGSQ
210 220 230 240 250
IRDEYLQNLV PFKEGDEYES KDLAELNRRL SATGWFNSVV VAPQFDKARE
260 270 280 290 300
TKVLPLTGVV SPRTENTIET GVGYSTDVGP RVKATWKKPW MNSYGHSLTT
310 320 330 340 350
STSISAPEQT LDFSYKMPLL KNPLEQYYLV QGGFKRTDLN DTESDSTTLV
360 370 380 390 400
ASRYWDLSSG WQRAINLRWS LDHFTQGEIT NTTMLFYPGV MISRTRSRGG
410 420 430 440 450
LMPTWGDSQR YSIDYSNTAW GSDVDFSVFQ AQNVWIRTLY DRHRFVTRGT
460 470 480 490 500
LGWIETGDFD KVPPDLRFFA GGDRSIRGYK YKSIAPKYAN GDLKGASKLI
510 520 530 540 550
TGSLEYQYNV TGKWWGAVFV DSGEAVSDIR RSDFKTGTGV GVRWESPVGP
560 570
IKLDFAVPVA DKDEHGLQFY IGLGPEL
Length:577
Mass (Da):64,796
Last modified:December 6, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i253D1D5BEA744D25
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U14003 Genomic DNA Translation: AAA97116.1
U00096 Genomic DNA Translation: AAC77177.1
AP009048 Genomic DNA Translation: BAE78221.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S56445

NCBI Reference Sequences

More...
RefSeqi
NP_418641.1, NC_000913.3
WP_001269327.1, NZ_LN832404.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC77177; AAC77177; b4220
BAE78221; BAE78221; BAE78221

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
948733

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ecj:JW4179
eco:b4220

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1411691.4.peg.2480

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA Translation: AAA97116.1
U00096 Genomic DNA Translation: AAC77177.1
AP009048 Genomic DNA Translation: BAE78221.1
PIRiS56445
RefSeqiNP_418641.1, NC_000913.3
WP_001269327.1, NZ_LN832404.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2LY3NMR-122-102[»]
4BZAX-ray1.84A22-275[»]
4C00X-ray2.25A22-577[»]
ProteinModelPortaliP0ADE4
SMRiP0ADE4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259308, 280 interactors
DIPiDIP-51058N
IntActiP0ADE4, 7 interactors
STRINGi316385.ECDH10B_4415

Protein family/group databases

TCDBi1.B.33.2.4 the outer membrane protein insertion porin (bam complex) (ompip) family

Proteomic databases

PaxDbiP0ADE4
PRIDEiP0ADE4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77177; AAC77177; b4220
BAE78221; BAE78221; BAE78221
GeneIDi948733
KEGGiecj:JW4179
eco:b4220
PATRICifig|1411691.4.peg.2480

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...
EchoBASEi
EB2406
EcoGeneiEG12513 tamA

Phylogenomic databases

eggNOGiENOG4105CFU Bacteria
COG0729 LUCA
HOGENOMiHOG000275353
InParanoidiP0ADE4
KOiK07278
PhylomeDBiP0ADE4

Enzyme and pathway databases

BioCyciEcoCyc:G7874-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P0ADE4

Family and domain databases

InterProiView protein in InterPro
IPR000184 Bac_surfAg_D15
IPR010827 BamA/TamA_POTRA
IPR039910 D15-like
IPR034746 POTRA
IPR035243 TamA_POTRA_Dom_1
PANTHERiPTHR12815 PTHR12815, 1 hit
PfamiView protein in Pfam
PF01103 Bac_surface_Ag, 1 hit
PF07244 POTRA, 1 hit
PF17243 POTRA_TamA_1, 1 hit
PROSITEiView protein in PROSITE
PS51779 POTRA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTAMA_ECOLI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P0ADE4
Secondary accession number(s): P39320, Q2M685
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: December 6, 2005
Last modified: November 7, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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