UniProtKB - P0AD30 (YFCA_ECOLI)
Protein
Probable membrane transporter protein YfcA
Gene
yfcA
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Biological processi
- response to heat Source: EcoCyc
Keywordsi
Biological process | Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11144-MONOMER ECOL316407:JW2324-MONOMER |
Protein family/group databases
TCDBi | 2.A.102.3.1 the 4-toluene sulfonate uptake permease (tsup) family |
Names & Taxonomyi
Protein namesi | Recommended name: Probable membrane transporter protein YfcA |
Gene namesi | Name:yfcA Ordered Locus Names:b2327, JW2324 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 7 | PeriplasmicSequence analysis | 7 | |
Transmembranei | 8 – 28 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 29 – 30 | CytoplasmicSequence analysis | 2 | |
Transmembranei | 31 – 51 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 52 – 84 | PeriplasmicSequence analysisAdd BLAST | 33 | |
Transmembranei | 85 – 105 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 106 – 111 | CytoplasmicSequence analysis | 6 | |
Transmembranei | 112 – 132 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 133 – 156 | PeriplasmicSequence analysisAdd BLAST | 24 | |
Transmembranei | 157 – 177 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 178 – 197 | CytoplasmicSequence analysisAdd BLAST | 20 | |
Transmembranei | 198 – 218 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 219 – 269 | PeriplasmicSequence analysisAdd BLAST | 51 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: EcoCyc
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000169187 | 1 – 269 | Probable membrane transporter protein YfcAAdd BLAST | 269 |
Proteomic databases
PaxDbi | P0AD30 |
PRIDEi | P0AD30 |
Interactioni
Protein-protein interaction databases
BioGridi | 4259583, 18 interactors |
IntActi | P0AD30, 2 interactors |
STRINGi | 511145.b2327 |
Family & Domainsi
Sequence similaritiesi
Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG4105EJ9 Bacteria COG0730 LUCA |
HOGENOMi | HOG000114880 |
InParanoidi | P0AD30 |
KOi | K07090 |
PhylomeDBi | P0AD30 |
Family and domain databases
InterProi | View protein in InterPro IPR002781 TM_pro_TauE-like |
Pfami | View protein in Pfam PF01925 TauE, 1 hit |
i Sequence
Sequence statusi: Complete.
P0AD30-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
METFNSLFMV SPLLLGVLFF VAMLAGFIDS IAGGGGLLTI PALMAAGMSP
60 70 80 90 100
ANALATNKLQ ACGGSISATI YFIRRKVVSL SDQKLNIAMT FVGSMSGALL
110 120 130 140 150
VQYVQADVLR QILPILVICI GLYFLLMPKL GEEDRQRRMY GLPFALIAGG
160 170 180 190 200
CVGFYDGFFG PAAGSFYALA FVTLCGFNLA KATAHAKLLN ATSNIGGLLL
210 220 230 240 250
FILGGKVIWA TGFVMLVGQF LGARMGSRLV LSKGQKLIRP MIVIVSAVMS
260
AKLLYDSHGQ EILHWLGMN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X16909 mRNA Translation: CAA34783.1 U00096 Genomic DNA Translation: AAC75387.1 AP009048 Genomic DNA Translation: BAA16183.1 |
PIRi | S08346 |
RefSeqi | NP_416830.1, NC_000913.3 WP_000447361.1, NZ_SSUR01000012.1 |
Genome annotation databases
EnsemblBacteriai | AAC75387; AAC75387; b2327 BAA16183; BAA16183; BAA16183 |
GeneIDi | 946808 |
KEGGi | ecj:JW2324 eco:b2327 |
PATRICi | fig|1411691.4.peg.4405 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X16909 mRNA Translation: CAA34783.1 U00096 Genomic DNA Translation: AAC75387.1 AP009048 Genomic DNA Translation: BAA16183.1 |
PIRi | S08346 |
RefSeqi | NP_416830.1, NC_000913.3 WP_000447361.1, NZ_SSUR01000012.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGridi | 4259583, 18 interactors |
IntActi | P0AD30, 2 interactors |
STRINGi | 511145.b2327 |
Protein family/group databases
TCDBi | 2.A.102.3.1 the 4-toluene sulfonate uptake permease (tsup) family |
Proteomic databases
PaxDbi | P0AD30 |
PRIDEi | P0AD30 |
Genome annotation databases
EnsemblBacteriai | AAC75387; AAC75387; b2327 BAA16183; BAA16183; BAA16183 |
GeneIDi | 946808 |
KEGGi | ecj:JW2324 eco:b2327 |
PATRICi | fig|1411691.4.peg.4405 |
Organism-specific databases
EchoBASEi | EB1134 |
Phylogenomic databases
eggNOGi | ENOG4105EJ9 Bacteria COG0730 LUCA |
HOGENOMi | HOG000114880 |
InParanoidi | P0AD30 |
KOi | K07090 |
PhylomeDBi | P0AD30 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11144-MONOMER ECOL316407:JW2324-MONOMER |
Miscellaneous databases
PROi | PR:P0AD30 |
Family and domain databases
InterProi | View protein in InterPro IPR002781 TM_pro_TauE-like |
Pfami | View protein in Pfam PF01925 TauE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YFCA_ECOLI | |
Accessioni | P0AD30Primary (citable) accession number: P0AD30 Secondary accession number(s): P14008 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 22, 2005 |
Last sequence update: | November 22, 2005 | |
Last modified: | November 13, 2019 | |
This is version 99 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Escherichia coli
Escherichia coli (strain K12): entries and cross-references to EcoGene