yeaL

Functionⁱ

Enzyme and pathway databases

BioCycⁱ	EcoCyc:G6975-MONOMER

BioCycⁱ

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: UPF0756 membrane protein YeaLUniRule annotation
Gene namesⁱ	Name:yeaLUniRule annotation Ordered Locus Names:b1789, JW1778
Organismⁱ	Escherichia coli (strain K12)
Taxonomic identifierⁱ	83333 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › Escherichia coli
Proteomesⁱ	UP000000318 Componentⁱ: Chromosome UP000000625 Componentⁱ: Chromosome

Organism-specific databases

EcoGeneⁱ	EG13498 yeaL

EcoGeneⁱ

EG13498 yeaL

Subcellular locationⁱ

Cell membrane
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_01874
; Multi-pass membrane protein
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_01874

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	14 – 34	HelicalUniRule annotationAdd BLAST	21
Transmembraneⁱ	51 – 71	HelicalUniRule annotationAdd BLAST	21
Transmembraneⁱ	86 – 106	HelicalUniRule annotationAdd BLAST	21
Transmembraneⁱ	121 – 141	HelicalUniRule annotationAdd BLAST	21

GO - Cellular componentⁱ

integral component of plasma membrane Source: UniProtKB-UniRule
plasma membrane
Source: EcoCyc
Inferred from direct assayⁱ
- 15919996

View the complete GO annotation on QuickGO ...

Keywords - Cellular componentⁱ

Cell membrane, Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000169019	1 – 148	UPF0756 membrane protein YeaLAdd BLAST		148

Proteomic databases

PaxDbⁱ	P0ACY6
PRIDEⁱ	P0ACY6

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	4260326, 14 interactors
STRINGⁱ	316385.ECDH10B_1927

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P0ACY6
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the UPF0756 family.UniRule annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	ENOG4108VMM Bacteria COG2707 LUCA
HOGENOMⁱ	HOG000021336
InParanoidⁱ	P0ACY6
PhylomeDBⁱ	P0ACY6

Family and domain databases

HAMAPⁱ	MF_01874 UPF0756, 1 hit
InterProⁱ	View protein in InterPro IPR007382 UPF0756_TM
PANTHERⁱ	PTHR38452 PTHR38452, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF04284 DUF441, 1 hit
ProDomⁱ	View protein in ProDom or Entries sharing at least one domain PD021096 DUF441_TM, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P0ACY6-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MFDVTLLILL GLAALGFISH NTTVAVSILV LIIVRVTPLS TFFPWIEKQG 
        60         70         80         90        100
LSIGIIILTI GVMAPIASGT LPPSTLIHSF LNWKSLVAIA VGVIVSWLGG 
       110        120        130        140 
RGVTLMGSQP QLVAGLLVGT VLGVALFRGV PVGPLIAAGL VSLIVGKQ

Length:148

Mass (Da):15,256

Last modified:November 22, 2005 - v1

Checksum:ⁱC24E91E1BA51FE93

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U00096 Genomic DNA Translation: AAC74859.1 AP009048 Genomic DNA Translation: BAA15588.1
PIRⁱ	E64939
NCBI Reference Sequences More...RefSeqⁱ	NP_416303.1, NC_000913.3 WP_000460707.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaⁱ	AAC74859; AAC74859; b1789 BAA15588; BAA15588; BAA15588
GeneIDⁱ	946307
KEGGⁱ	ecj:JW1778 eco:b1789
PATRICⁱ	fig\|1411691.4.peg.466

Protein	Similar proteins		Species	Score	Length	Source
P0ACY6	UPF0756 membrane protein YeaL		ECO24		148	UniRef100_A7ZMQ9
UPF0756 membrane protein YeaL		ECO45		148
UPF0756 membrane protein YeaL		ECO7I		148
UPF0756 membrane protein YeaL		ECO81		148
UPF0756 membrane protein YeaL		ECO8A		148
+160

Protein	Similar proteins		Species	Score	Length	Source
P0ACY6	UPF0756 membrane protein YeaL		SALTY		134	UniRef90_Q8ZPW7
UPF0756 membrane protein YeaL		ECO24		148
UPF0756 membrane protein YeaL		ECO45		148
UPF0756 membrane protein YeaL		ECO7I		148
UPF0756 membrane protein YeaL		ECO81		148
+177

Protein	Similar proteins		Species	Score	Length	Source
P0ACY6	UPF0756 membrane protein YeaL		SALAR		148	UniRef50_A9MFI4
UPF0756 membrane protein YeaL		ECO27		148
UPF0756 membrane protein YeaL		SHIDS		148
UPF0756 membrane protein YeaL		ESCF3		148
UPF0756 membrane protein CKO_01811		CITK8		148
+962

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U00096 Genomic DNA Translation: AAC74859.1 AP009048 Genomic DNA Translation: BAA15588.1
PIRⁱ	E64939
RefSeqⁱ	NP_416303.1, NC_000913.3 WP_000460707.1, NZ_LN832404.1

3D structure databases

ProteinModelPortalⁱ	P0ACY6
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	4260326, 14 interactors
STRINGⁱ	316385.ECDH10B_1927

Proteomic databases

PaxDbⁱ	P0ACY6
PRIDEⁱ	P0ACY6

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAC74859; AAC74859; b1789 BAA15588; BAA15588; BAA15588
GeneIDⁱ	946307
KEGGⁱ	ecj:JW1778 eco:b1789
PATRICⁱ	fig\|1411691.4.peg.466

Organism-specific databases

EchoBASEⁱ	EB3271
EcoGeneⁱ	EG13498 yeaL

Phylogenomic databases

eggNOGⁱ	ENOG4108VMM Bacteria COG2707 LUCA
HOGENOMⁱ	HOG000021336
InParanoidⁱ	P0ACY6
PhylomeDBⁱ	P0ACY6

Enzyme and pathway databases

BioCycⁱ	EcoCyc:G6975-MONOMER

BioCycⁱ

EcoCyc:G6975-MONOMER

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P0ACY6

PROⁱ

PR:P0ACY6

Family and domain databases

HAMAPⁱ	MF_01874 UPF0756, 1 hit
InterProⁱ	View protein in InterPro IPR007382 UPF0756_TM
PANTHERⁱ	PTHR38452 PTHR38452, 1 hit
Pfamⁱ	View protein in Pfam PF04284 DUF441, 1 hit
ProDomⁱ	View protein in ProDom or Entries sharing at least one domain PD021096 DUF441_TM, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	YEAL_ECOLI
Accessionⁱ	P0ACY6Primary (citable) accession number: P0ACY6 Secondary accession number(s): O07965, O07967, P76240
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	November 22, 2005
	Last sequence update:	November 22, 2005
	Last modified:	November 7, 2018
	This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Uncharacterized protein families (UPF)
List of uncharacterized protein family (UPF) entries
Escherichia coli
Escherichia coli (strain K12): entries and cross-references to EcoGene

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P0ACY6 (YEAL_ECOLI)

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UPF0756 membrane protein YeaL

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

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Functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ