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Protein

HTH-type transcriptional regulator ZntR

Gene

zntR

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Zinc-responsive transcriptional regulator of zntA.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi114ZincBy similarity1
Metal bindingi115ZincBy similarity1
Metal bindingi119ZincBy similarity1
Metal bindingi124ZincBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi4 – 23H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator ZntR
Alternative name(s):
Zn(II)-responsive regulator of zntA
Gene namesi
Name:zntR
Ordered Locus Names:Z4662, ECs4157
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000981611 – 141HTH-type transcriptional regulator ZntRAdd BLAST141

Proteomic databases

PRIDEiP0ACS6

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi155864.Z4662

Structurei

3D structure databases

ProteinModelPortaliP0ACS6
SMRiP0ACS6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 70HTH merR-typePROSITE-ProRule annotationAdd BLAST70

Phylogenomic databases

eggNOGiENOG4105W1Y Bacteria
COG0789 LUCA
HOGENOMiHOG000266084
KOiK13638
OMAiCAVETIR

Family and domain databases

InterProiView protein in InterPro
IPR009061 DNA-bd_dom_put_sf
IPR000551 MerR-type_HTH_dom
IPR011788 ZntR
PfamiView protein in Pfam
PF13411 MerR_1, 1 hit
PRINTSiPR00040 HTHMERR
SMARTiView protein in SMART
SM00422 HTH_MERR, 1 hit
SUPFAMiSSF46955 SSF46955, 1 hit
TIGRFAMsiTIGR02043 ZntR, 1 hit
PROSITEiView protein in PROSITE
PS00552 HTH_MERR_1, 1 hit
PS50937 HTH_MERR_2, 1 hit

Sequencei

Sequence statusi: Complete.

P0ACS6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYRIGELAKM AEVTPDTIRY YEKQQMMEHE VRTEGGFRLY TESDLQRLKF
60 70 80 90 100
IRHARQLGFS LESIRELLSI RIDPEHHTCQ ESKGIVQERL QEVEARIAEL
110 120 130 140
QSMQRSLQRL NDACCGTAHS SVYCSILEAL EQGASGVKSG C
Length:141
Mass (Da):16,179
Last modified:November 22, 2005 - v1
Checksum:iEB451201C8BDCE20
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA Translation: AAG58413.2
BA000007 Genomic DNA Translation: BAB37580.1
PIRiE91148
RefSeqiNP_312184.1, NC_002695.1
WP_000285607.1, NZ_NOKN01000002.1

Genome annotation databases

EnsemblBacteriaiAAG58413; AAG58413; Z4662
BAB37580; BAB37580; BAB37580
GeneIDi915990
KEGGiece:Z4662
ecs:ECs4157
PATRICifig|386585.9.peg.4340

Similar proteinsi

Entry informationi

Entry nameiZNTR_ECO57
AccessioniPrimary (citable) accession number: P0ACS6
Secondary accession number(s): P36676
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: May 23, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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