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Protein

Right origin-binding protein

Gene

rob

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Binds to the right arm of the replication origin oriC of the chromosome. Rob binding may influence the formation of the nucleoprotein structure, required for oriC function in the initiation of replication.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi24 – 43H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:PD04418

Names & Taxonomyi

Protein namesi
Recommended name:
Right origin-binding protein
Gene namesi
Name:rob
Ordered Locus Names:b4396, JW4359
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11366 rob

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001945781 – 289Right origin-binding proteinAdd BLAST289

Proteomic databases

PaxDbiP0ACI0
PRIDEiP0ACI0

Interactioni

Protein-protein interaction databases

BioGridi4259321, 108 interactors
DIPiDIP-47868N
IntActiP0ACI0, 17 interactors
STRINGi316385.ECDH10B_4554

Structurei

Secondary structure

1289
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP0ACI0
SMRiP0ACI0
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0ACI0

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105UEI Bacteria
COG2207 LUCA
HOGENOMiHOG000127886
InParanoidiP0ACI0
KOiK05804
OMAiFWRQYLG
PhylomeDBiP0ACI0

Family and domain databases

Gene3Di3.20.80.10, 1 hit
InterProiView protein in InterPro
IPR010499 AraC_E-bd
IPR029442 GyrI-like
IPR009057 Homeobox-like_sf
IPR018060 HTH_AraC
IPR018062 HTH_AraC-typ_CS
IPR011256 Reg_factor_effector_dom_sf
IPR020449 Tscrpt_reg_HTH_AraC-type
PfamiView protein in Pfam
PF06445 GyrI-like, 1 hit
PF12833 HTH_18, 1 hit
PRINTSiPR00032 HTHARAC
SMARTiView protein in SMART
SM00871 AraC_E_bind, 1 hit
SM00342 HTH_ARAC, 1 hit
SUPFAMiSSF46689 SSF46689, 2 hits
SSF55136 SSF55136, 1 hit
PROSITEiView protein in PROSITE
PS00041 HTH_ARAC_FAMILY_1, 1 hit
PS01124 HTH_ARAC_FAMILY_2, 1 hit

Sequencei

Sequence statusi: Complete.

P0ACI0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDQAGIIRDL LIWLEGHLDQ PLSLDNVAAK AGYSKWHLQR MFKDVTGHAI
60 70 80 90 100
GAYIRARRLS KSAVALRLTA RPILDIALQY RFDSQQTFTR AFKKQFAQTP
110 120 130 140 150
ALYRRSPEWS AFGIRPPLRL GEFTMPEHKF VTLEDTPLIG VTQSYSCSLE
160 170 180 190 200
QISDFRHEMR YQFWHDFLGN APTIPPVLYG LNETRPSQDK DDEQEVFYTT
210 220 230 240 250
ALAQDQADGY VLTGHPVMLQ GGEYVMFTYE GLGTGVQEFI LTVYGTCMPM
260 270 280
LNLTRRKGQD IERYYPAEDA KAGDRPINLR CELLIPIRR
Length:289
Mass (Da):33,145
Last modified:November 22, 2005 - v1
Checksum:i4436B1A04BE86A93
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M97495 Genomic DNA Translation: AAA24569.1
U14003 Genomic DNA Translation: AAA97292.1
U00096 Genomic DNA Translation: AAC77349.1
AP009048 Genomic DNA Translation: BAE78385.1
PIRiJU0158
RefSeqiNP_418813.1, NC_000913.3
WP_000371666.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC77349; AAC77349; b4396
BAE78385; BAE78385; BAE78385
GeneIDi948916
KEGGiecj:JW4359
eco:b4396
PATRICifig|1411691.4.peg.2288

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M97495 Genomic DNA Translation: AAA24569.1
U14003 Genomic DNA Translation: AAA97292.1
U00096 Genomic DNA Translation: AAC77349.1
AP009048 Genomic DNA Translation: BAE78385.1
PIRiJU0158
RefSeqiNP_418813.1, NC_000913.3
WP_000371666.1, NZ_LN832404.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1D5YX-ray2.70A/B/C/D3-289[»]
ProteinModelPortaliP0ACI0
SMRiP0ACI0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259321, 108 interactors
DIPiDIP-47868N
IntActiP0ACI0, 17 interactors
STRINGi316385.ECDH10B_4554

Proteomic databases

PaxDbiP0ACI0
PRIDEiP0ACI0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77349; AAC77349; b4396
BAE78385; BAE78385; BAE78385
GeneIDi948916
KEGGiecj:JW4359
eco:b4396
PATRICifig|1411691.4.peg.2288

Organism-specific databases

EchoBASEiEB1340
EcoGeneiEG11366 rob

Phylogenomic databases

eggNOGiENOG4105UEI Bacteria
COG2207 LUCA
HOGENOMiHOG000127886
InParanoidiP0ACI0
KOiK05804
OMAiFWRQYLG
PhylomeDBiP0ACI0

Enzyme and pathway databases

BioCyciEcoCyc:PD04418

Miscellaneous databases

EvolutionaryTraceiP0ACI0
PROiPR:P0ACI0

Family and domain databases

Gene3Di3.20.80.10, 1 hit
InterProiView protein in InterPro
IPR010499 AraC_E-bd
IPR029442 GyrI-like
IPR009057 Homeobox-like_sf
IPR018060 HTH_AraC
IPR018062 HTH_AraC-typ_CS
IPR011256 Reg_factor_effector_dom_sf
IPR020449 Tscrpt_reg_HTH_AraC-type
PfamiView protein in Pfam
PF06445 GyrI-like, 1 hit
PF12833 HTH_18, 1 hit
PRINTSiPR00032 HTHARAC
SMARTiView protein in SMART
SM00871 AraC_E_bind, 1 hit
SM00342 HTH_ARAC, 1 hit
SUPFAMiSSF46689 SSF46689, 2 hits
SSF55136 SSF55136, 1 hit
PROSITEiView protein in PROSITE
PS00041 HTH_ARAC_FAMILY_1, 1 hit
PS01124 HTH_ARAC_FAMILY_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiROB_ECOLI
AccessioniPrimary (citable) accession number: P0ACI0
Secondary accession number(s): P27292, Q2M5S1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 22, 2005
Last modified: September 12, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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Main funding by: National Institutes of Health

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