UniProtKB - P0ACI0 (ROB_ECOLI)
Protein
Right origin-binding protein
Gene
rob
Organism
Escherichia coli (strain K12)
Status
Functioni
Binds to the right arm of the replication origin oriC of the chromosome. Rob binding may influence the formation of the nucleoprotein structure, required for oriC function in the initiation of replication.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 25 – 46 | H-T-H motifPROSITE-ProRule annotationAdd BLAST | 22 | |
DNA bindingi | 73 – 96 | H-T-H motifPROSITE-ProRule annotationAdd BLAST | 24 |
GO - Molecular functioni
- DNA-binding transcription factor activity Source: InterPro
- sequence-specific DNA binding Source: EcoliWiki
Keywordsi
Molecular function | DNA-binding |
Enzyme and pathway databases
BioCyci | EcoCyc:PD04418 |
Names & Taxonomyi
Protein namesi | Recommended name: Right origin-binding protein |
Gene namesi | Name:rob Ordered Locus Names:b4396, JW4359 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000194578 | 1 – 289 | Right origin-binding proteinAdd BLAST | 289 |
Proteomic databases
jPOSTi | P0ACI0 |
PaxDbi | P0ACI0 |
PRIDEi | P0ACI0 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4259321, 108 interactors |
DIPi | DIP-47868N |
IntActi | P0ACI0, 17 interactors |
STRINGi | 511145.b4396 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P0ACI0 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P0ACI0 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 8 – 106 | HTH araC/xylS-typePROSITE-ProRule annotationAdd BLAST | 99 |
Phylogenomic databases
eggNOGi | COG2207, Bacteria COG3708, Bacteria |
HOGENOMi | CLU_000445_81_1_6 |
InParanoidi | P0ACI0 |
PhylomeDBi | P0ACI0 |
Family and domain databases
Gene3Di | 3.20.80.10, 1 hit |
InterProi | View protein in InterPro IPR010499, AraC_E-bd IPR029442, GyrI-like IPR009057, Homeobox-like_sf IPR018060, HTH_AraC IPR018062, HTH_AraC-typ_CS IPR011256, Reg_factor_effector_dom_sf IPR020449, Tscrpt_reg_HTH_AraC-type |
Pfami | View protein in Pfam PF06445, GyrI-like, 1 hit PF12833, HTH_18, 1 hit |
PRINTSi | PR00032, HTHARAC |
SMARTi | View protein in SMART SM00871, AraC_E_bind, 1 hit SM00342, HTH_ARAC, 1 hit |
SUPFAMi | SSF46689, SSF46689, 2 hits SSF55136, SSF55136, 1 hit |
PROSITEi | View protein in PROSITE PS00041, HTH_ARAC_FAMILY_1, 1 hit PS01124, HTH_ARAC_FAMILY_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P0ACI0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDQAGIIRDL LIWLEGHLDQ PLSLDNVAAK AGYSKWHLQR MFKDVTGHAI
60 70 80 90 100
GAYIRARRLS KSAVALRLTA RPILDIALQY RFDSQQTFTR AFKKQFAQTP
110 120 130 140 150
ALYRRSPEWS AFGIRPPLRL GEFTMPEHKF VTLEDTPLIG VTQSYSCSLE
160 170 180 190 200
QISDFRHEMR YQFWHDFLGN APTIPPVLYG LNETRPSQDK DDEQEVFYTT
210 220 230 240 250
ALAQDQADGY VLTGHPVMLQ GGEYVMFTYE GLGTGVQEFI LTVYGTCMPM
260 270 280
LNLTRRKGQD IERYYPAEDA KAGDRPINLR CELLIPIRR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M97495 Genomic DNA Translation: AAA24569.1 U14003 Genomic DNA Translation: AAA97292.1 U00096 Genomic DNA Translation: AAC77349.1 AP009048 Genomic DNA Translation: BAE78385.1 |
PIRi | JU0158 |
RefSeqi | NP_418813.1, NC_000913.3 WP_000371666.1, NZ_STEB01000033.1 |
Genome annotation databases
EnsemblBacteriai | AAC77349; AAC77349; b4396 BAE78385; BAE78385; BAE78385 |
GeneIDi | 58461406 948916 |
KEGGi | ecj:JW4359 eco:b4396 |
PATRICi | fig|1411691.4.peg.2288 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M97495 Genomic DNA Translation: AAA24569.1 U14003 Genomic DNA Translation: AAA97292.1 U00096 Genomic DNA Translation: AAC77349.1 AP009048 Genomic DNA Translation: BAE78385.1 |
PIRi | JU0158 |
RefSeqi | NP_418813.1, NC_000913.3 WP_000371666.1, NZ_STEB01000033.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1D5Y | X-ray | 2.70 | A/B/C/D | 3-289 | [»] | |
SMRi | P0ACI0 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 4259321, 108 interactors |
DIPi | DIP-47868N |
IntActi | P0ACI0, 17 interactors |
STRINGi | 511145.b4396 |
Proteomic databases
jPOSTi | P0ACI0 |
PaxDbi | P0ACI0 |
PRIDEi | P0ACI0 |
Genome annotation databases
EnsemblBacteriai | AAC77349; AAC77349; b4396 BAE78385; BAE78385; BAE78385 |
GeneIDi | 58461406 948916 |
KEGGi | ecj:JW4359 eco:b4396 |
PATRICi | fig|1411691.4.peg.2288 |
Organism-specific databases
EchoBASEi | EB1340 |
Phylogenomic databases
eggNOGi | COG2207, Bacteria COG3708, Bacteria |
HOGENOMi | CLU_000445_81_1_6 |
InParanoidi | P0ACI0 |
PhylomeDBi | P0ACI0 |
Enzyme and pathway databases
BioCyci | EcoCyc:PD04418 |
Miscellaneous databases
EvolutionaryTracei | P0ACI0 |
PROi | PR:P0ACI0 |
Family and domain databases
Gene3Di | 3.20.80.10, 1 hit |
InterProi | View protein in InterPro IPR010499, AraC_E-bd IPR029442, GyrI-like IPR009057, Homeobox-like_sf IPR018060, HTH_AraC IPR018062, HTH_AraC-typ_CS IPR011256, Reg_factor_effector_dom_sf IPR020449, Tscrpt_reg_HTH_AraC-type |
Pfami | View protein in Pfam PF06445, GyrI-like, 1 hit PF12833, HTH_18, 1 hit |
PRINTSi | PR00032, HTHARAC |
SMARTi | View protein in SMART SM00871, AraC_E_bind, 1 hit SM00342, HTH_ARAC, 1 hit |
SUPFAMi | SSF46689, SSF46689, 2 hits SSF55136, SSF55136, 1 hit |
PROSITEi | View protein in PROSITE PS00041, HTH_ARAC_FAMILY_1, 1 hit PS01124, HTH_ARAC_FAMILY_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ROB_ECOLI | |
Accessioni | P0ACI0Primary (citable) accession number: P0ACI0 Secondary accession number(s): P27292, Q2M5S1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 22, 2005 |
Last sequence update: | November 22, 2005 | |
Last modified: | April 7, 2021 | |
This is version 122 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references