UniProtKB - P0ACD2 (WCAF_ECOLI)
Protein
Putative colanic acid biosynthesis acetyltransferase WcaF
Gene
wcaF
Organism
Escherichia coli (strain K12)
Status
Functioni
: slime polysaccharide biosynthesis Pathwayi
This protein is involved in the pathway slime polysaccharide biosynthesis, which is part of Slime biogenesis.View all proteins of this organism that are known to be involved in the pathway slime polysaccharide biosynthesis and in Slime biogenesis.
GO - Molecular functioni
- O-acetyltransferase activity Source: EcoCyc
GO - Biological processi
- colanic acid biosynthetic process Source: EcoCyc
- lipopolysaccharide biosynthetic process Source: UniProtKB-KW
- single-species biofilm formation Source: EcoCyc
- slime layer polysaccharide biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Acyltransferase, Transferase |
Biological process | Lipopolysaccharide biosynthesis |
Enzyme and pathway databases
BioCyci | EcoCyc:G7099-MONOMER MetaCyc:G7099-MONOMER |
UniPathwayi | UPA00936 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:wcaF Ordered Locus Names:b2054, JW2039 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000068736 | 1 – 182 | Putative colanic acid biosynthesis acetyltransferase WcaFAdd BLAST | 182 |
Proteomic databases
PaxDbi | P0ACD2 |
PRIDEi | P0ACD2 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4259689, 200 interactors |
IntActi | P0ACD2, 1 interactor |
STRINGi | 511145.b2054 |
Family & Domainsi
Sequence similaritiesi
Belongs to the transferase hexapeptide repeat family.Curated
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | COG0110, Bacteria |
HOGENOMi | CLU_051638_7_2_6 |
InParanoidi | P0ACD2 |
PhylomeDBi | P0ACD2 |
Family and domain databases
InterProi | View protein in InterPro IPR024005, Colanic_acid_synth_WcaF IPR001451, Hexapep IPR018357, Hexapep_transf_CS IPR011004, Trimer_LpxA-like_sf |
Pfami | View protein in Pfam PF00132, Hexapep, 1 hit |
SUPFAMi | SSF51161, SSF51161, 1 hit |
TIGRFAMsi | TIGR04008, WcaF, 1 hit |
PROSITEi | View protein in PROSITE PS00101, HEXAPEP_TRANSFERASES, 1 hit |
i Sequence
Sequence statusi: Complete.
P0ACD2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQDLSGFSVP KGFRGGNAIK VQLWWAVQAT IFAWSPQVLY RWRAFLLRLF
60 70 80 90 100
GAKIGKNVVI RPSVKITYPW KLTLGDYAWV GDDVNLYTLG EITIGAHSVI
110 120 130 140 150
SQKSYLCTGS HDHASQHFTI NATPIVIGEK CWLATDVFVA PGVTIGDGTV
160 170 180
VGARSSVFKS LPANVVCRGN PAVVIRERVE TE
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 50 | F → L in AAC77841 (Ref. 2) Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U38473 Genomic DNA Translation: AAC77841.1 U00096 Genomic DNA Translation: AAC75115.1 AP009048 Genomic DNA Translation: BAA15910.1 |
PIRi | E64971 |
RefSeqi | NP_416558.1, NC_000913.3 WP_001153547.1, NZ_STEB01000002.1 |
Genome annotation databases
EnsemblBacteriai | AAC75115; AAC75115; b2054 BAA15910; BAA15910; BAA15910 |
GeneIDi | 48105306 946578 |
KEGGi | ecj:JW2039 eco:b2054 |
PATRICi | fig|1411691.4.peg.197 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U38473 Genomic DNA Translation: AAC77841.1 U00096 Genomic DNA Translation: AAC75115.1 AP009048 Genomic DNA Translation: BAA15910.1 |
PIRi | E64971 |
RefSeqi | NP_416558.1, NC_000913.3 WP_001153547.1, NZ_STEB01000002.1 |
3D structure databases
SMRi | P0ACD2 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4259689, 200 interactors |
IntActi | P0ACD2, 1 interactor |
STRINGi | 511145.b2054 |
Proteomic databases
PaxDbi | P0ACD2 |
PRIDEi | P0ACD2 |
Genome annotation databases
EnsemblBacteriai | AAC75115; AAC75115; b2054 BAA15910; BAA15910; BAA15910 |
GeneIDi | 48105306 946578 |
KEGGi | ecj:JW2039 eco:b2054 |
PATRICi | fig|1411691.4.peg.197 |
Organism-specific databases
EchoBASEi | EB3344 |
Phylogenomic databases
eggNOGi | COG0110, Bacteria |
HOGENOMi | CLU_051638_7_2_6 |
InParanoidi | P0ACD2 |
PhylomeDBi | P0ACD2 |
Enzyme and pathway databases
UniPathwayi | UPA00936 |
BioCyci | EcoCyc:G7099-MONOMER MetaCyc:G7099-MONOMER |
Miscellaneous databases
PROi | PR:P0ACD2 |
Family and domain databases
InterProi | View protein in InterPro IPR024005, Colanic_acid_synth_WcaF IPR001451, Hexapep IPR018357, Hexapep_transf_CS IPR011004, Trimer_LpxA-like_sf |
Pfami | View protein in Pfam PF00132, Hexapep, 1 hit |
SUPFAMi | SSF51161, SSF51161, 1 hit |
TIGRFAMsi | TIGR04008, WcaF, 1 hit |
PROSITEi | View protein in PROSITE PS00101, HEXAPEP_TRANSFERASES, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | WCAF_ECOLI | |
Accessioni | P0ACD2Primary (citable) accession number: P0ACD2 Secondary accession number(s): P71240, P76383 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 8, 2005 |
Last sequence update: | November 8, 2005 | |
Last modified: | December 2, 2020 | |
This is version 92 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families