We will be switching to the new UniProt website on Tuesday, June 28. Please explore and share your feedback.
Take me to UniProt BETA
UniProtKB - P0ACC9 (WCAB_ECOLI)
Protein
Putative colanic acid biosynthesis acetyltransferase WcaB
Gene
wcaB
Organism
Escherichia coli (strain K12)
Status
Functioni
: slime polysaccharide biosynthesis Pathwayi
This protein is involved in the pathway slime polysaccharide biosynthesis, which is part of Slime biogenesis.View all proteins of this organism that are known to be involved in the pathway slime polysaccharide biosynthesis and in Slime biogenesis.
GO - Molecular functioni
- acetyltransferase activity Source: EcoliWiki
- O-acetyltransferase activity Source: EcoCyc
- serine O-acetyltransferase activity Source: GO_Central
GO - Biological processi
- colanic acid biosynthetic process Source: EcoCyc
- cysteine biosynthetic process from serine Source: InterPro
- lipopolysaccharide biosynthetic process Source: UniProtKB-KW
- slime layer polysaccharide biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Acyltransferase, Transferase |
Biological process | Lipopolysaccharide biosynthesis |
Enzyme and pathway databases
BioCyci | EcoCyc:G7103-MONOMER |
UniPathwayi | UPA00936 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:wcaB Ordered Locus Names:b2058, JW2043 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000068733 | 1 – 162 | Putative colanic acid biosynthesis acetyltransferase WcaBAdd BLAST | 162 |
Proteomic databases
PaxDbi | P0ACC9 |
PRIDEi | P0ACC9 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260674, 269 interactors |
DIPi | DIP-48109N |
IntActi | P0ACC9, 1 interactor |
STRINGi | 511145.b2058 |
Family & Domainsi
Sequence similaritiesi
Belongs to the transferase hexapeptide repeat family.Curated
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | COG1045, Bacteria |
HOGENOMi | CLU_051638_10_2_6 |
InParanoidi | P0ACC9 |
OMAi | FGRWRYT |
PhylomeDBi | P0ACC9 |
Family and domain databases
CDDi | cd03354, LbH_SAT, 1 hit |
InterProi | View protein in InterPro IPR024027, Colanic_acid_synth_WcaB IPR001451, Hexapep IPR018357, Hexapep_transf_CS IPR045304, LbH_SAT IPR005881, Ser_O-AcTrfase IPR011004, Trimer_LpxA-like_sf |
Pfami | View protein in Pfam PF00132, Hexapep, 1 hit |
PIRSFi | PIRSF000441, CysE, 1 hit |
SUPFAMi | SSF51161, SSF51161, 1 hit |
TIGRFAMsi | TIGR04016, WcaB, 1 hit |
PROSITEi | View protein in PROSITE PS00101, HEXAPEP_TRANSFERASES, 1 hit |
i Sequence
Sequence statusi: Complete.
P0ACC9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLEDLRANSW SLRPCCMVLA YRVAHFCSVW RKKNVLNNLW AAPLLVLYRI
60 70 80 90 100
ITECFFGYEI QAAATIGRRF TIHHGYAVVI NKNVVAGDDF TIRHGVTIGN
110 120 130 140 150
RGADNMACPH IGNGVELGAN VIILGDITLG NNVTVGAGSV VLDSVPDNAL
160
VVGEKARVKV IK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U38473 Genomic DNA Translation: AAC77837.1 U00096 Genomic DNA Translation: AAC75119.1 AP009048 Genomic DNA Translation: BAA15911.1 |
PIRi | A64972 |
RefSeqi | NP_416562.1, NC_000913.3 WP_000888740.1, NZ_SSUV01000030.1 |
Genome annotation databases
EnsemblBacteriai | AAC75119; AAC75119; b2058 BAA15911; BAA15911; BAA15911 |
GeneIDi | 66674044 946573 |
KEGGi | ecj:JW2043 eco:b2058 |
PATRICi | fig|1411691.4.peg.193 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U38473 Genomic DNA Translation: AAC77837.1 U00096 Genomic DNA Translation: AAC75119.1 AP009048 Genomic DNA Translation: BAA15911.1 |
PIRi | A64972 |
RefSeqi | NP_416562.1, NC_000913.3 WP_000888740.1, NZ_SSUV01000030.1 |
3D structure databases
AlphaFoldDBi | P0ACC9 |
SMRi | P0ACC9 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4260674, 269 interactors |
DIPi | DIP-48109N |
IntActi | P0ACC9, 1 interactor |
STRINGi | 511145.b2058 |
Proteomic databases
PaxDbi | P0ACC9 |
PRIDEi | P0ACC9 |
Genome annotation databases
EnsemblBacteriai | AAC75119; AAC75119; b2058 BAA15911; BAA15911; BAA15911 |
GeneIDi | 66674044 946573 |
KEGGi | ecj:JW2043 eco:b2058 |
PATRICi | fig|1411691.4.peg.193 |
Organism-specific databases
EchoBASEi | EB3340 |
Phylogenomic databases
eggNOGi | COG1045, Bacteria |
HOGENOMi | CLU_051638_10_2_6 |
InParanoidi | P0ACC9 |
OMAi | FGRWRYT |
PhylomeDBi | P0ACC9 |
Enzyme and pathway databases
UniPathwayi | UPA00936 |
BioCyci | EcoCyc:G7103-MONOMER |
Miscellaneous databases
PROi | PR:P0ACC9 |
Family and domain databases
CDDi | cd03354, LbH_SAT, 1 hit |
InterProi | View protein in InterPro IPR024027, Colanic_acid_synth_WcaB IPR001451, Hexapep IPR018357, Hexapep_transf_CS IPR045304, LbH_SAT IPR005881, Ser_O-AcTrfase IPR011004, Trimer_LpxA-like_sf |
Pfami | View protein in Pfam PF00132, Hexapep, 1 hit |
PIRSFi | PIRSF000441, CysE, 1 hit |
SUPFAMi | SSF51161, SSF51161, 1 hit |
TIGRFAMsi | TIGR04016, WcaB, 1 hit |
PROSITEi | View protein in PROSITE PS00101, HEXAPEP_TRANSFERASES, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | WCAB_ECOLI | |
Accessioni | P0ACC9Primary (citable) accession number: P0ACC9 Secondary accession number(s): P77558 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 8, 2005 |
Last sequence update: | November 8, 2005 | |
Last modified: | May 25, 2022 | |
This is version 103 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families