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Protein

Zinc uptake regulation protein

Gene

zur

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Acts as a negative controlling element, employing Zn2+ as a cofactor to bind the operator of the repressed genes (znuACB).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation
LigandZinc

Enzyme and pathway databases

BioCyciEcoCyc:EG11929-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc uptake regulation protein
Short name:
Zinc uptake regulator
Gene namesi
Name:zur
Synonyms:yjbK
Ordered Locus Names:b4046, JW5714
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11929 zur

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000955921 – 171Zinc uptake regulation proteinAdd BLAST171

Proteomic databases

EPDiP0AC51
PaxDbiP0AC51
PRIDEiP0AC51

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
itself2EBI-16126292,EBI-16126292

GO - Molecular functioni

Protein-protein interaction databases

BioGridi4261723, 7 interactors
DIPiDIP-12953N
STRINGi316385.ECDH10B_4235

Structurei

Secondary structure

1171
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP0AC51
SMRiP0AC51
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Fur family.Curated

Phylogenomic databases

eggNOGiENOG4105MYN Bacteria
COG0735 LUCA
HOGENOMiHOG000014146
InParanoidiP0AC51
KOiK09823
PhylomeDBiP0AC51

Family and domain databases

CDDicd07153 Fur_like, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR002481 FUR
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR33202 PTHR33202, 1 hit
PfamiView protein in Pfam
PF01475 FUR, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit

Sequencei

Sequence statusi: Complete.

P0AC51-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKTTTQELL AQAEKICAQR NVRLTPQRLE VLRLMSLQDG AISAYDLLDL
60 70 80 90 100
LREAEPQAKP PTVYRALDFL LEQGFVHKVE STNSYVLCHL FDQPTHTSAM
110 120 130 140 150
FICDRCGAVK EECAEGVEDI MHTLAAKMGF ALRHNVIEAH GLCAACVEVE
160 170
ACRHPEQCQH DHSVQVKKKP R
Length:171
Mass (Da):19,254
Last modified:November 8, 2005 - v1
Checksum:i84B712B1BBF00D41
GO

Sequence cautioni

The sequence AAC43140 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00006 Genomic DNA Translation: AAC43140.1 Different initiation.
U00096 Genomic DNA Translation: AAC77016.2
AP009048 Genomic DNA Translation: BAE78048.1
PIRiE65212
RefSeqiNP_418470.4, NC_000913.3
WP_001295691.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC77016; AAC77016; b4046
BAE78048; BAE78048; BAE78048
GeneIDi948552
KEGGiecj:JW5714
eco:b4046
PATRICifig|511145.12.peg.4163

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00006 Genomic DNA Translation: AAC43140.1 Different initiation.
U00096 Genomic DNA Translation: AAC77016.2
AP009048 Genomic DNA Translation: BAE78048.1
PIRiE65212
RefSeqiNP_418470.4, NC_000913.3
WP_001295691.1, NZ_LN832404.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4MTDX-ray2.50A/B/C/D1-171[»]
4MTEX-ray2.50A/B/C/D1-171[»]
ProteinModelPortaliP0AC51
SMRiP0AC51
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261723, 7 interactors
DIPiDIP-12953N
STRINGi316385.ECDH10B_4235

Proteomic databases

EPDiP0AC51
PaxDbiP0AC51
PRIDEiP0AC51

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77016; AAC77016; b4046
BAE78048; BAE78048; BAE78048
GeneIDi948552
KEGGiecj:JW5714
eco:b4046
PATRICifig|511145.12.peg.4163

Organism-specific databases

EchoBASEiEB1873
EcoGeneiEG11929 zur

Phylogenomic databases

eggNOGiENOG4105MYN Bacteria
COG0735 LUCA
HOGENOMiHOG000014146
InParanoidiP0AC51
KOiK09823
PhylomeDBiP0AC51

Enzyme and pathway databases

BioCyciEcoCyc:EG11929-MONOMER

Miscellaneous databases

PROiPR:P0AC51

Family and domain databases

CDDicd07153 Fur_like, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR002481 FUR
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR33202 PTHR33202, 1 hit
PfamiView protein in Pfam
PF01475 FUR, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiZUR_ECOLI
AccessioniPrimary (citable) accession number: P0AC51
Secondary accession number(s): P32692, P76784, Q2M6Q8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 8, 2005
Last modified: November 7, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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Main funding by: National Institutes of Health

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