UniProtKB - P0AC05 (FLIP_ECOLI)
Protein
Flagellar biosynthetic protein FliP
Gene
fliP
Organism
Escherichia coli (strain K12)
Status
Functioni
Plays a role in the flagellum-specific transport system.
GO - Biological processi
- bacterial-type flagellum organization Source: UniProtKB-KW
- protein secretion Source: InterPro
Keywordsi
Biological process | Bacterial flagellum biogenesis, Bacterial flagellum protein export, Protein transport, Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11975-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Flagellar biosynthetic protein FliP |
Gene namesi | Name:fliP Synonyms:flaR Ordered Locus Names:b1948, JW1932 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
- Cell inner membrane 1 Publication; Multi-pass membrane protein 1 Publication
- Bacterial flagellum basal body 1 Publication
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 45 – 65 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 88 – 108 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 185 – 205 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 209 – 229 | HelicalSequence analysisAdd BLAST | 21 |
GO - Cellular componenti
- bacterial-type flagellum basal body Source: UniProtKB-SubCell
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: EcoCyc
Keywords - Cellular componenti
Bacterial flagellum, Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 21 | By similarityAdd BLAST | 21 | |
ChainiPRO_0000009535 | 22 – 245 | Flagellar biosynthetic protein FliPAdd BLAST | 224 |
Proteomic databases
PaxDbi | P0AC05 |
PRIDEi | P0AC05 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4261044, 438 interactors |
STRINGi | 511145.b1948 |
Family & Domainsi
Sequence similaritiesi
Belongs to the FliP/MopC/SpaP family.Curated
Keywords - Domaini
Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG1338, Bacteria |
HOGENOMi | CLU_042028_0_1_6 |
InParanoidi | P0AC05 |
PhylomeDBi | P0AC05 |
Family and domain databases
InterProi | View protein in InterPro IPR005837, FliP IPR005838, T3SS_IM_P |
PANTHERi | PTHR30587, PTHR30587, 1 hit PTHR30587:SF0, PTHR30587:SF0, 1 hit |
Pfami | View protein in Pfam PF00813, FliP, 1 hit |
PRINTSi | PR00951, FLGBIOSNFLIP PR01302, TYPE3IMPPROT |
TIGRFAMsi | TIGR01103, fliP, 1 hit |
PROSITEi | View protein in PROSITE PS01060, FLIP_1, 1 hit PS01061, FLIP_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P0AC05-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRRLLSVAPV LLWLITPLAF AQLPGITSQP LPGGGQSWSL PVQTLVFITS
60 70 80 90 100
LTFIPAILLM MTSFTRIIIV FGLLRNALGT PSAPPNQVLL GLALFLTFFI
110 120 130 140 150
MSPVIDKIYV DAYQPFSEEK ISMQEALEKG AQPLREFMLR QTREADLGLF
160 170 180 190 200
ARLANTGPLQ GPEAVPMRIL LPAYVTSELK TAFQIGFTIF IPFLIIDLVI
210 220 230 240
ASVLMALGMM MVPPATIALP FKLMLFVLVD GWQLLVGSLA QSFYS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L22182 Genomic DNA Translation: AAC36859.1 AP009048 Genomic DNA Translation: BAA15773.1 U00096 Genomic DNA Translation: AAC75015.1 |
PIRi | B36869 |
RefSeqi | NP_416458.1, NC_000913.3 WP_001253441.1, NZ_STEB01000050.1 |
Genome annotation databases
EnsemblBacteriai | AAC75015; AAC75015; b1948 BAA15773; BAA15773; BAA15773 |
GeneIDi | 946462 |
KEGGi | ecj:JW1932 eco:b1948 |
PATRICi | fig|1411691.4.peg.303 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L22182 Genomic DNA Translation: AAC36859.1 AP009048 Genomic DNA Translation: BAA15773.1 U00096 Genomic DNA Translation: AAC75015.1 |
PIRi | B36869 |
RefSeqi | NP_416458.1, NC_000913.3 WP_001253441.1, NZ_STEB01000050.1 |
3D structure databases
SMRi | P0AC05 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4261044, 438 interactors |
STRINGi | 511145.b1948 |
Proteomic databases
PaxDbi | P0AC05 |
PRIDEi | P0AC05 |
Genome annotation databases
EnsemblBacteriai | AAC75015; AAC75015; b1948 BAA15773; BAA15773; BAA15773 |
GeneIDi | 946462 |
KEGGi | ecj:JW1932 eco:b1948 |
PATRICi | fig|1411691.4.peg.303 |
Organism-specific databases
EchoBASEi | EB1918 |
Phylogenomic databases
eggNOGi | COG1338, Bacteria |
HOGENOMi | CLU_042028_0_1_6 |
InParanoidi | P0AC05 |
PhylomeDBi | P0AC05 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11975-MONOMER |
Miscellaneous databases
PROi | PR:P0AC05 |
Family and domain databases
InterProi | View protein in InterPro IPR005837, FliP IPR005838, T3SS_IM_P |
PANTHERi | PTHR30587, PTHR30587, 1 hit PTHR30587:SF0, PTHR30587:SF0, 1 hit |
Pfami | View protein in Pfam PF00813, FliP, 1 hit |
PRINTSi | PR00951, FLGBIOSNFLIP PR01302, TYPE3IMPPROT |
TIGRFAMsi | TIGR01103, fliP, 1 hit |
PROSITEi | View protein in PROSITE PS01060, FLIP_1, 1 hit PS01061, FLIP_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | FLIP_ECOLI | |
Accessioni | P0AC05Primary (citable) accession number: P0AC05 Secondary accession number(s): P33133 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 8, 2005 |
Last sequence update: | November 8, 2005 | |
Last modified: | December 2, 2020 | |
This is version 103 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families