UniProtKB - P0ABY4 (FLAW_ECOLI)

BLAST

>sp|P0ABY4|FLAW_ECOLI Flavodoxin 2 OS=Escherichia coli (strain K12) OX=83333 GN=fldB PE=1 SV=1
MNMGLFYGSSTCYTEMAAEKIRDIIGPELVTLHNLKDDSPKLMEQYDVLILGIPTWDFGE
IQEDWEAVWDQLDDLNLEGKIVALYGLGDQLGYGEWFLDALGMLHDKLSTKGVKFVGYWP
TEGYEFTSPKPVIADGQLFVGLALDETNQYDLSDERIQSWCEQILNEMAEHYA

Align
Format
Add to basket Added to basket
History
Entry version 88 (07 Nov 2018)
Sequence version 1 (25 Oct 2005)
Previous versions | rss
Other tutorials and videos
Help video
Feedback

Protein

Flavodoxin 2

Gene

fldB

Organism

Escherichia coli (strain K12)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Low-potential electron donor to a number of redox enzymes.Curated

Cofactorⁱ

FMN

GO - Molecular functionⁱ

electron transfer activity Source: InterPro
FMN binding
Source: EcoCyc
Inferred from direct assayⁱ
- 25380767

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Electron transport, Transport
Ligand	Flavoprotein, FMN

Enzyme and pathway databases

BioCycⁱ	EcoCyc:FLAVODOXIN2-MONOMER MetaCyc:FLAVODOXIN2-MONOMER

BioCycⁱ

EcoCyc:FLAVODOXIN2-MONOMER
MetaCyc:FLAVODOXIN2-MONOMER

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Flavodoxin 2
Gene namesⁱ	Name:fldB Ordered Locus Names:b2895, JW2863
Organismⁱ	Escherichia coli (strain K12)
Taxonomic identifierⁱ	83333 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › Escherichia coli
Proteomesⁱ	UP000000318 Componentⁱ: Chromosome UP000000625 Componentⁱ: Chromosome

Organism-specific databases

EcoGeneⁱ	EG12697 fldB

EcoGeneⁱ

EG12697 fldB

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000171626	1 – 173	Flavodoxin 2Add BLAST		173

Proteomic databases

PaxDbⁱ	P0ABY4
PRIDEⁱ	P0ABY4

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	4262340, 10 interactors
IntActⁱ	P0ABY4, 8 interactors
STRINGⁱ	316385.ECDH10B_3069

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Beta strandⁱ	3 – 7	Combined sources	5
Beta strandⁱ	10 – 12	Combined sources	3
Helixⁱ	13 – 25	Combined sources	13
Turnⁱ	27 – 29	Combined sources	3
Beta strandⁱ	30 – 34	Combined sources	5
Turnⁱ	35 – 37	Combined sources	3
Helixⁱ	40 – 44	Combined sources	5
Beta strandⁱ	46 – 56	Combined sources	11
Turnⁱ	57 – 59	Combined sources	3
Helixⁱ	63 – 68	Combined sources	6
Helixⁱ	71 – 74	Combined sources	4
Beta strandⁱ	81 – 88	Combined sources	8
Turnⁱ	90 – 93	Combined sources	4
Turnⁱ	95 – 98	Combined sources	4
Helixⁱ	99 – 110	Combined sources	12
Beta strandⁱ	114 – 116	Combined sources	3
Beta strandⁱ	129 – 133	Combined sources	5
Turnⁱ	134 – 137	Combined sources	4
Beta strandⁱ	138 – 148	Combined sources	11
Helixⁱ	149 – 151	Combined sources	3
Helixⁱ	153 – 171	Combined sources	19

Show more details

3D structure databases

ProteinModelPortalⁱ	P0ABY4
SMRⁱ	P0ABY4
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	3 – 165	Flavodoxin-likePROSITE-ProRule annotationAdd BLAST		163

Sequence similaritiesⁱ

Belongs to the flavodoxin family.Curated

Phylogenomic databases

eggNOGⁱ	ENOG41071R3 Bacteria COG0716 LUCA
HOGENOMⁱ	HOG000030543
InParanoidⁱ	P0ABY4
KEGG Orthology (KO) More...KOⁱ	K03840
PhylomeDBⁱ	P0ABY4

Family and domain databases

Gene3Dⁱ	3.40.50.360, 1 hit
InterProⁱ	View protein in InterPro IPR008254 Flavodoxin/NO_synth IPR001226 Flavodoxin_CS IPR010086 Flavodoxin_lc IPR029039 Flavoprotein-like_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00258 Flavodoxin_1, 1 hit
PIRSFⁱ	PIRSF038996 FldA, 1 hit
SUPFAMⁱ	SSF52218 SSF52218, 1 hit
TIGRFAMsⁱ	TIGR01752 flav_long, 1 hit
PROSITEⁱ	View protein in PROSITE PS00201 FLAVODOXIN, 1 hit PS50902 FLAVODOXIN_LIKE, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P0ABY4-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MNMGLFYGSS TCYTEMAAEK IRDIIGPELV TLHNLKDDSP KLMEQYDVLI 
        60         70         80         90        100
LGIPTWDFGE IQEDWEAVWD QLDDLNLEGK IVALYGLGDQ LGYGEWFLDA 
       110        120        130        140        150
LGMLHDKLST KGVKFVGYWP TEGYEFTSPK PVIADGQLFV GLALDETNQY 
       160        170 
DLSDERIQSW CEQILNEMAE HYA

Length:173

Mass (Da):19,700

Last modified:October 25, 2005 - v1

Checksum:ⁱ89338715D106A68C

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	115	F → C in CAA88140 (Ref. 1) Curated		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	Z48060 Genomic DNA Translation: CAA88140.1 U28375 Genomic DNA Translation: AAA83076.1 U00096 Genomic DNA Translation: AAC75933.1 AP009048 Genomic DNA Translation: BAE76960.1
PIRⁱ	G65073
NCBI Reference Sequences More...RefSeqⁱ	NP_417371.1, NC_000913.3 WP_001055874.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaⁱ	AAC75933; AAC75933; b2895 BAE76960; BAE76960; BAE76960
GeneIDⁱ	947361
KEGGⁱ	ecj:JW2863 eco:b2895
PATRICⁱ	fig\|1411691.4.peg.3838

Protein	Similar proteins		Species	Score	Length	Source
P0ABY4	Flavodoxin 2		ECO57		173	UniRef100_P0ABY6
Flavodoxin 2		ECOL6		173
Flavodoxin-2		Shigella sp.		173
Flavodoxin		Escherichia coli O145 str. RM9872		173
Flavodoxin		Klebsiella pneumoniae IS22		173
+161

Protein	Similar proteins		Species	Score	Length	Source
P0ABY4	Flavodoxin 2		ECO57		173	UniRef90_P0ABY6
Flavodoxin 2		ECOL6		173
Flavodoxin 2		SALTI		173
Flavodoxin 2		SALTY		173
Flavodoxin-2		Shigella sp.		173
+658

Protein	Similar proteins		Species	Score	Length	Source
P0ABY4	Flavodoxin 2		ECO57		173	UniRef50_P0ABY6
Flavodoxin 2		ECOL6		173
Flavodoxin 2		SALTI		173
Flavodoxin 2		SALTY		173
Flavodoxin-2		Shigella sp.		173
+965

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	Z48060 Genomic DNA Translation: CAA88140.1 U28375 Genomic DNA Translation: AAA83076.1 U00096 Genomic DNA Translation: AAC75933.1 AP009048 Genomic DNA Translation: BAE76960.1
PIRⁱ	G65073
RefSeqⁱ	NP_417371.1, NC_000913.3 WP_001055874.1, NZ_LN832404.1

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	2MT9	NMR	-	A	1-173	[»]
	2MTB	NMR	-	A	1-173	[»]
ProteinModelPortalⁱ	P0ABY4
SMRⁱ	P0ABY4
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	4262340, 10 interactors
IntActⁱ	P0ABY4, 8 interactors
STRINGⁱ	316385.ECDH10B_3069

Proteomic databases

PaxDbⁱ	P0ABY4
PRIDEⁱ	P0ABY4

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAC75933; AAC75933; b2895 BAE76960; BAE76960; BAE76960
GeneIDⁱ	947361
KEGGⁱ	ecj:JW2863 eco:b2895
PATRICⁱ	fig\|1411691.4.peg.3838

Organism-specific databases

EchoBASEⁱ	EB2559
EcoGeneⁱ	EG12697 fldB

Phylogenomic databases

eggNOGⁱ	ENOG41071R3 Bacteria COG0716 LUCA
HOGENOMⁱ	HOG000030543
InParanoidⁱ	P0ABY4
KOⁱ	K03840
PhylomeDBⁱ	P0ABY4

Enzyme and pathway databases

BioCycⁱ	EcoCyc:FLAVODOXIN2-MONOMER MetaCyc:FLAVODOXIN2-MONOMER

BioCycⁱ

EcoCyc:FLAVODOXIN2-MONOMER
MetaCyc:FLAVODOXIN2-MONOMER

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P0ABY4

PROⁱ

PR:P0ABY4

Family and domain databases

Gene3Dⁱ	3.40.50.360, 1 hit
InterProⁱ	View protein in InterPro IPR008254 Flavodoxin/NO_synth IPR001226 Flavodoxin_CS IPR010086 Flavodoxin_lc IPR029039 Flavoprotein-like_sf
Pfamⁱ	View protein in Pfam PF00258 Flavodoxin_1, 1 hit
PIRSFⁱ	PIRSF038996 FldA, 1 hit
SUPFAMⁱ	SSF52218 SSF52218, 1 hit
TIGRFAMsⁱ	TIGR01752 flav_long, 1 hit
PROSITEⁱ	View protein in PROSITE PS00201 FLAVODOXIN, 1 hit PS50902 FLAVODOXIN_LIKE, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	FLAW_ECOLI
Accessionⁱ	P0ABY4Primary (citable) accession number: P0ABY4 Secondary accession number(s): P41050, Q2M9U6
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 25, 2005
	Last sequence update:	October 25, 2005
	Last modified:	November 7, 2018
	This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
PDB cross-references
Index of Protein Data Bank (PDB) cross-references
Escherichia coli
Escherichia coli (strain K12): entries and cross-references to EcoGene

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P0ABY4 (FLAW_ECOLI)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Flavodoxin 2

fldB

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ