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Protein

Flavodoxin 2

Gene

fldB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Low-potential electron donor to a number of redox enzymes.Curated

Cofactori

GO - Molecular functioni

  • electron transfer activity Source: InterPro
  • FMN binding Source: EcoCyc

Keywordsi

Biological processElectron transport, Transport
LigandFlavoprotein, FMN

Enzyme and pathway databases

BioCyciEcoCyc:FLAVODOXIN2-MONOMER
MetaCyc:FLAVODOXIN2-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Flavodoxin 2
Gene namesi
Name:fldB
Ordered Locus Names:b2895, JW2863
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12697 fldB

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001716261 – 173Flavodoxin 2Add BLAST173

Proteomic databases

PaxDbiP0ABY4
PRIDEiP0ABY4

Interactioni

Protein-protein interaction databases

BioGridi4262340, 10 interactors
IntActiP0ABY4, 8 interactors
STRINGi316385.ECDH10B_3069

Structurei

Secondary structure

1173
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP0ABY4
SMRiP0ABY4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 165Flavodoxin-likePROSITE-ProRule annotationAdd BLAST163

Sequence similaritiesi

Belongs to the flavodoxin family.Curated

Phylogenomic databases

eggNOGiENOG41071R3 Bacteria
COG0716 LUCA
HOGENOMiHOG000030543
InParanoidiP0ABY4
KOiK03840
PhylomeDBiP0ABY4

Family and domain databases

Gene3Di3.40.50.360, 1 hit
InterProiView protein in InterPro
IPR008254 Flavodoxin/NO_synth
IPR001226 Flavodoxin_CS
IPR010086 Flavodoxin_lc
IPR029039 Flavoprotein-like_sf
PfamiView protein in Pfam
PF00258 Flavodoxin_1, 1 hit
PIRSFiPIRSF038996 FldA, 1 hit
SUPFAMiSSF52218 SSF52218, 1 hit
TIGRFAMsiTIGR01752 flav_long, 1 hit
PROSITEiView protein in PROSITE
PS00201 FLAVODOXIN, 1 hit
PS50902 FLAVODOXIN_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

P0ABY4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNMGLFYGSS TCYTEMAAEK IRDIIGPELV TLHNLKDDSP KLMEQYDVLI
60 70 80 90 100
LGIPTWDFGE IQEDWEAVWD QLDDLNLEGK IVALYGLGDQ LGYGEWFLDA
110 120 130 140 150
LGMLHDKLST KGVKFVGYWP TEGYEFTSPK PVIADGQLFV GLALDETNQY
160 170
DLSDERIQSW CEQILNEMAE HYA
Length:173
Mass (Da):19,700
Last modified:October 25, 2005 - v1
Checksum:i89338715D106A68C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti115F → C in CAA88140 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48060 Genomic DNA Translation: CAA88140.1
U28375 Genomic DNA Translation: AAA83076.1
U00096 Genomic DNA Translation: AAC75933.1
AP009048 Genomic DNA Translation: BAE76960.1
PIRiG65073
RefSeqiNP_417371.1, NC_000913.3
WP_001055874.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75933; AAC75933; b2895
BAE76960; BAE76960; BAE76960
GeneIDi947361
KEGGiecj:JW2863
eco:b2895
PATRICifig|1411691.4.peg.3838

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48060 Genomic DNA Translation: CAA88140.1
U28375 Genomic DNA Translation: AAA83076.1
U00096 Genomic DNA Translation: AAC75933.1
AP009048 Genomic DNA Translation: BAE76960.1
PIRiG65073
RefSeqiNP_417371.1, NC_000913.3
WP_001055874.1, NZ_LN832404.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2MT9NMR-A1-173[»]
2MTBNMR-A1-173[»]
ProteinModelPortaliP0ABY4
SMRiP0ABY4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262340, 10 interactors
IntActiP0ABY4, 8 interactors
STRINGi316385.ECDH10B_3069

Proteomic databases

PaxDbiP0ABY4
PRIDEiP0ABY4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75933; AAC75933; b2895
BAE76960; BAE76960; BAE76960
GeneIDi947361
KEGGiecj:JW2863
eco:b2895
PATRICifig|1411691.4.peg.3838

Organism-specific databases

EchoBASEiEB2559
EcoGeneiEG12697 fldB

Phylogenomic databases

eggNOGiENOG41071R3 Bacteria
COG0716 LUCA
HOGENOMiHOG000030543
InParanoidiP0ABY4
KOiK03840
PhylomeDBiP0ABY4

Enzyme and pathway databases

BioCyciEcoCyc:FLAVODOXIN2-MONOMER
MetaCyc:FLAVODOXIN2-MONOMER

Miscellaneous databases

PROiPR:P0ABY4

Family and domain databases

Gene3Di3.40.50.360, 1 hit
InterProiView protein in InterPro
IPR008254 Flavodoxin/NO_synth
IPR001226 Flavodoxin_CS
IPR010086 Flavodoxin_lc
IPR029039 Flavoprotein-like_sf
PfamiView protein in Pfam
PF00258 Flavodoxin_1, 1 hit
PIRSFiPIRSF038996 FldA, 1 hit
SUPFAMiSSF52218 SSF52218, 1 hit
TIGRFAMsiTIGR01752 flav_long, 1 hit
PROSITEiView protein in PROSITE
PS00201 FLAVODOXIN, 1 hit
PS50902 FLAVODOXIN_LIKE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiFLAW_ECOLI
AccessioniPrimary (citable) accession number: P0ABY4
Secondary accession number(s): P41050, Q2M9U6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: October 25, 2005
Last modified: November 7, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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Main funding by: National Institutes of Health

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