UniProtKB - P0ABH4 (MRED_ECOLI)
Protein
Rod shape-determining protein MreD
Gene
mreD
Organism
Escherichia coli (strain K12)
Status
Functioni
Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
GO - Biological processi
- regulation of cell shape Source: EcoCyc
Keywordsi
Biological process | Cell shape |
Enzyme and pathway databases
BioCyci | EcoCyc:EG10610-MONOMER |
Protein family/group databases
TCDBi | 9.B.157.1.3, the cell shape-determining mrebcd (mrebcd) family |
Names & Taxonomyi
Protein namesi | Recommended name: Rod shape-determining protein MreD |
Gene namesi | Name:mreD Ordered Locus Names:b3249, JW3218 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 9 | PeriplasmicSequence analysis | 9 | |
Transmembranei | 10 – 30 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 31 – 51 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 52 – 55 | PeriplasmicSequence analysis | 4 | |
Transmembranei | 56 – 76 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 77 – 105 | CytoplasmicSequence analysisAdd BLAST | 29 | |
Transmembranei | 106 – 126 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 127 – 131 | PeriplasmicSequence analysis | 5 | |
Transmembranei | 132 – 152 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 153 – 162 | CytoplasmicSequence analysis | 10 |
GO - Cellular componenti
- integral component of plasma membrane Source: EcoCyc
- plasma membrane Source: EcoCyc
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000062770 | 1 – 162 | Rod shape-determining protein MreDAdd BLAST | 162 |
Proteomic databases
PaxDbi | P0ABH4 |
PRIDEi | P0ABH4 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4262449, 394 interactors |
DIPi | DIP-10257N |
STRINGi | 511145.b3249 |
Family & Domainsi
Sequence similaritiesi
Belongs to the MreD family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG2891, Bacteria |
HOGENOMi | CLU_119315_0_1_6 |
InParanoidi | P0ABH4 |
Family and domain databases
InterProi | View protein in InterPro IPR007227, Cell_shape_determining_MreD IPR026034, MreD_proteobac |
PANTHERi | PTHR37484, PTHR37484, 1 hit |
Pfami | View protein in Pfam PF04093, MreD, 1 hit |
PIRSFi | PIRSF018472, MreD_proteobac, 1 hit |
TIGRFAMsi | TIGR03426, shape_MreD, 1 hit |
i Sequence
Sequence statusi: Complete.
P0ABH4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASYRSQGRW VIWLSFLIAL LLQIMPWPDN LIVFRPNWVL LILLYWILAL
60 70 80 90 100
PHRVNVGTGF VMGAILDLIS GSTLGVRVLA MSIIAYLVAL KYQLFRNLAL
110 120 130 140 150
WQQALVVMLL SLVVDIIVFW AEFLVINVSF RPEVFWSSVV NGVLWPWIFL
160
LMRKVRQQFA VQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M31792 Genomic DNA Translation: AAA24156.1 U18997 Genomic DNA Translation: AAA58052.1 U00096 Genomic DNA Translation: AAC76281.1 AP009048 Genomic DNA Translation: BAE77291.1 X57166 Genomic DNA Translation: CAA40455.1 |
PIRi | JV0060 |
RefSeqi | NP_417715.1, NC_000913.3 WP_000179409.1, NZ_STEB01000012.1 |
Genome annotation databases
EnsemblBacteriai | AAC76281; AAC76281; b3249 BAE77291; BAE77291; BAE77291 |
GeneIDi | 49582798 947756 |
KEGGi | ecj:JW3218 eco:b3249 |
PATRICi | fig|1411691.4.peg.3480 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M31792 Genomic DNA Translation: AAA24156.1 U18997 Genomic DNA Translation: AAA58052.1 U00096 Genomic DNA Translation: AAC76281.1 AP009048 Genomic DNA Translation: BAE77291.1 X57166 Genomic DNA Translation: CAA40455.1 |
PIRi | JV0060 |
RefSeqi | NP_417715.1, NC_000913.3 WP_000179409.1, NZ_STEB01000012.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4262449, 394 interactors |
DIPi | DIP-10257N |
STRINGi | 511145.b3249 |
Protein family/group databases
TCDBi | 9.B.157.1.3, the cell shape-determining mrebcd (mrebcd) family |
Proteomic databases
PaxDbi | P0ABH4 |
PRIDEi | P0ABH4 |
Genome annotation databases
EnsemblBacteriai | AAC76281; AAC76281; b3249 BAE77291; BAE77291; BAE77291 |
GeneIDi | 49582798 947756 |
KEGGi | ecj:JW3218 eco:b3249 |
PATRICi | fig|1411691.4.peg.3480 |
Organism-specific databases
EchoBASEi | EB0605 |
Phylogenomic databases
eggNOGi | COG2891, Bacteria |
HOGENOMi | CLU_119315_0_1_6 |
InParanoidi | P0ABH4 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG10610-MONOMER |
Miscellaneous databases
PROi | PR:P0ABH4 |
Family and domain databases
InterProi | View protein in InterPro IPR007227, Cell_shape_determining_MreD IPR026034, MreD_proteobac |
PANTHERi | PTHR37484, PTHR37484, 1 hit |
Pfami | View protein in Pfam PF04093, MreD, 1 hit |
PIRSFi | PIRSF018472, MreD_proteobac, 1 hit |
TIGRFAMsi | TIGR03426, shape_MreD, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | MRED_ECOLI | |
Accessioni | P0ABH4Primary (citable) accession number: P0ABH4 Secondary accession number(s): P16927, Q2M8W5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 25, 2005 |
Last sequence update: | October 25, 2005 | |
Last modified: | December 2, 2020 | |
This is version 99 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families