UniProtKB - P0ABA6 (ATPG_ECOLI)
Protein
ATP synthase gamma chain
Gene
atpG
Organism
Escherichia coli (strain K12)
Status
Functioni
Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF0 complex.
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- proton-transporting ATPase activity, rotational mechanism Source: EcoCyc
- proton-transporting ATP synthase activity, rotational mechanism Source: EcoCyc
GO - Biological processi
- ATP synthesis coupled proton transport Source: GO_Central
- plasma membrane ATP synthesis coupled proton transport Source: UniProtKB-UniRule
Keywordsi
Biological process | ATP synthesis, Hydrogen ion transport, Ion transport, Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:ATPG-MONOMER MetaCyc:ATPG-MONOMER |
Protein family/group databases
TCDBi | 3.A.2.1.1, the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: ATP synthase gamma chainAlternative name(s): ATP synthase F1 sector gamma subunit F-ATPase gamma subunit |
Gene namesi | Name:atpG Synonyms:papC, uncG Ordered Locus Names:b3733, JW3711 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell inner membrane 1 Publication; Peripheral membrane protein 1 Publication
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- membrane Source: UniProtKB
- proton-transporting ATP synthase complex, catalytic core F(1) Source: EcoliWiki
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, CF(1), MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000073282 | 1 – 287 | ATP synthase gamma chainAdd BLAST | 287 |
Proteomic databases
jPOSTi | P0ABA6 |
PaxDbi | P0ABA6 |
PRIDEi | P0ABA6 |
Interactioni
Subunit structurei
F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c.
1 PublicationBinary interactionsi
P0ABA6
With | #Exp. | IntAct |
---|---|---|
atpC [P0A6E6] | 5 | EBI-544306,EBI-544362 |
Protein-protein interaction databases
BioGRIDi | 852545, 6 interactors |
ComplexPortali | CPX-4022, ATP synthase complex |
DIPi | DIP-35938N |
IntActi | P0ABA6, 15 interactors |
STRINGi | 511145.b3733 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P0ABA6 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P0ABA6 |
Family & Domainsi
Sequence similaritiesi
Belongs to the ATPase gamma chain family.Curated
Phylogenomic databases
eggNOGi | COG0224, Bacteria |
HOGENOMi | CLU_050669_0_1_6 |
InParanoidi | P0ABA6 |
PhylomeDBi | P0ABA6 |
Family and domain databases
CDDi | cd12151, F1-ATPase_gamma, 1 hit |
HAMAPi | MF_00815, ATP_synth_gamma_bact, 1 hit |
InterProi | View protein in InterPro IPR035968, ATP_synth_F1_ATPase_gsu IPR000131, ATP_synth_F1_gsu IPR023632, ATP_synth_F1_gsu_CS |
PANTHERi | PTHR11693, PTHR11693, 1 hit |
Pfami | View protein in Pfam PF00231, ATP-synt, 1 hit |
PRINTSi | PR00126, ATPASEGAMMA |
SUPFAMi | SSF52943, SSF52943, 1 hit |
TIGRFAMsi | TIGR01146, ATPsyn_F1gamma, 1 hit |
PROSITEi | View protein in PROSITE PS00153, ATPASE_GAMMA, 1 hit |
i Sequence
Sequence statusi: Complete.
P0ABA6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAGAKEIRSK IASVQNTQKI TKAMEMVAAS KMRKSQDRMA ASRPYAETMR
60 70 80 90 100
KVIGHLAHGN LEYKHPYLED RDVKRVGYLV VSTDRGLCGG LNINLFKKLL
110 120 130 140 150
AEMKTWTDKG VQCDLAMIGS KGVSFFNSVG GNVVAQVTGM GDNPSLSELI
160 170 180 190 200
GPVKVMLQAY DEGRLDKLYI VSNKFINTMS QVPTISQLLP LPASDDDDLK
210 220 230 240 250
HKSWDYLYEP DPKALLDTLL RRYVESQVYQ GVVENLASEQ AARMVAMKAA
260 270 280
TDNGGSLIKE LQLVYNKARQ ASITQELTEI VSGAAAV
Sequence cautioni
The sequence CAA23597 differs from that shown. Reason: Frameshift.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X01631 Genomic DNA Translation: CAA25781.1 V00267 Genomic DNA Translation: CAA23526.1 J01594 Genomic DNA Translation: AAA24736.1 Frameshift. V00312 Genomic DNA Translation: CAA23597.1 Sequence problems. M25464 Genomic DNA Translation: AAA83874.1 L10328 Genomic DNA Translation: AAA62085.1 U00096 Genomic DNA Translation: AAC76756.1 AP009048 Genomic DNA Translation: BAE77555.1 M34095 Genomic DNA Translation: AAA24742.1 |
PIRi | A01038, PWECG |
RefSeqi | NP_418189.1, NC_000913.3 WP_000896498.1, NZ_STEB01000015.1 |
Genome annotation databases
EnsemblBacteriai | AAC76756; AAC76756; b3733 BAE77555; BAE77555; BAE77555 |
GeneIDi | 58461066 948243 |
KEGGi | ecj:JW3711 eco:b3733 |
PATRICi | fig|1411691.4.peg.2967 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X01631 Genomic DNA Translation: CAA25781.1 V00267 Genomic DNA Translation: CAA23526.1 J01594 Genomic DNA Translation: AAA24736.1 Frameshift. V00312 Genomic DNA Translation: CAA23597.1 Sequence problems. M25464 Genomic DNA Translation: AAA83874.1 L10328 Genomic DNA Translation: AAA62085.1 U00096 Genomic DNA Translation: AAC76756.1 AP009048 Genomic DNA Translation: BAE77555.1 M34095 Genomic DNA Translation: AAA24742.1 |
PIRi | A01038, PWECG |
RefSeqi | NP_418189.1, NC_000913.3 WP_000896498.1, NZ_STEB01000015.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1D8S | X-ray | 4.40 | G | 1-287 | [»] | |
1FS0 | X-ray | 2.10 | G | 19-248 | [»] | |
3OAA | X-ray | 3.26 | G/O/W/e | 2-287 | [»] | |
5T4O | electron microscopy | 6.90 | G | 1-287 | [»] | |
5T4P | electron microscopy | 7.77 | G | 1-287 | [»] | |
5T4Q | electron microscopy | 8.53 | G | 1-287 | [»] | |
6OQR | electron microscopy | 3.10 | G | 1-287 | [»] | |
6OQS | electron microscopy | 3.30 | G | 1-287 | [»] | |
6OQT | electron microscopy | 3.10 | G | 1-287 | [»] | |
6OQU | electron microscopy | 3.20 | G | 1-287 | [»] | |
6OQV | electron microscopy | 3.30 | G | 1-287 | [»] | |
6OQW | electron microscopy | 3.10 | G | 1-287 | [»] | |
6PQV | electron microscopy | 3.30 | G | 1-287 | [»] | |
6WNQ | electron microscopy | 3.40 | G | 1-287 | [»] | |
6WNR | electron microscopy | 3.30 | G | 1-287 | [»] | |
SMRi | P0ABA6 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 852545, 6 interactors |
ComplexPortali | CPX-4022, ATP synthase complex |
DIPi | DIP-35938N |
IntActi | P0ABA6, 15 interactors |
STRINGi | 511145.b3733 |
Protein family/group databases
TCDBi | 3.A.2.1.1, the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily |
Proteomic databases
jPOSTi | P0ABA6 |
PaxDbi | P0ABA6 |
PRIDEi | P0ABA6 |
Genome annotation databases
EnsemblBacteriai | AAC76756; AAC76756; b3733 BAE77555; BAE77555; BAE77555 |
GeneIDi | 58461066 948243 |
KEGGi | ecj:JW3711 eco:b3733 |
PATRICi | fig|1411691.4.peg.2967 |
Organism-specific databases
EchoBASEi | EB0102 |
Phylogenomic databases
eggNOGi | COG0224, Bacteria |
HOGENOMi | CLU_050669_0_1_6 |
InParanoidi | P0ABA6 |
PhylomeDBi | P0ABA6 |
Enzyme and pathway databases
BioCyci | EcoCyc:ATPG-MONOMER MetaCyc:ATPG-MONOMER |
Miscellaneous databases
EvolutionaryTracei | P0ABA6 |
PROi | PR:P0ABA6 |
Family and domain databases
CDDi | cd12151, F1-ATPase_gamma, 1 hit |
HAMAPi | MF_00815, ATP_synth_gamma_bact, 1 hit |
InterProi | View protein in InterPro IPR035968, ATP_synth_F1_ATPase_gsu IPR000131, ATP_synth_F1_gsu IPR023632, ATP_synth_F1_gsu_CS |
PANTHERi | PTHR11693, PTHR11693, 1 hit |
Pfami | View protein in Pfam PF00231, ATP-synt, 1 hit |
PRINTSi | PR00126, ATPASEGAMMA |
SUPFAMi | SSF52943, SSF52943, 1 hit |
TIGRFAMsi | TIGR01146, ATPsyn_F1gamma, 1 hit |
PROSITEi | View protein in PROSITE PS00153, ATPASE_GAMMA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ATPG_ECOLI | |
Accessioni | P0ABA6Primary (citable) accession number: P0ABA6 Secondary accession number(s): P00837, P00838, Q2M851 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 21, 1986 |
Last sequence update: | July 21, 1986 | |
Last modified: | April 7, 2021 | |
This is version 128 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families