We will be switching to the new UniProt website on Tuesday, June 28. Please explore and share your feedback.
Take me to UniProt BETA
UniProtKB - P0AAJ1 (YNFG_ECOLI)
Protein
Probable anaerobic dimethyl sulfoxide reductase chain YnfG
Gene
ynfG
Organism
Escherichia coli (strain K12)
Status
Functioni
Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.
Cofactori
[4Fe-4S] clusterBy similarityNote: Binds 4 [4Fe-4S] clusters.By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 14 | Iron-sulfur (4Fe-4S) 1By similarity | 1 | |
Metal bindingi | 17 | Iron-sulfur (4Fe-4S) 1By similarity | 1 | |
Metal bindingi | 20 | Iron-sulfur (4Fe-4S) 1By similarity | 1 | |
Metal bindingi | 24 | Iron-sulfur (4Fe-4S) 2By similarity | 1 | |
Metal bindingi | 67 | Iron-sulfur (4Fe-4S) 3By similarity | 1 | |
Metal bindingi | 70 | Iron-sulfur (4Fe-4S) 3By similarity | 1 | |
Metal bindingi | 75 | Iron-sulfur (4Fe-4S) 3By similarity | 1 | |
Metal bindingi | 79 | Iron-sulfur (4Fe-4S) 4By similarity | 1 | |
Metal bindingi | 99 | Iron-sulfur (4Fe-4S) 4By similarity | 1 | |
Metal bindingi | 102 | Iron-sulfur (4Fe-4S) 4By similarity | 1 | |
Metal bindingi | 105 | Iron-sulfur (4Fe-4S) 4By similarity | 1 | |
Metal bindingi | 109 | Iron-sulfur (4Fe-4S) 3By similarity | 1 | |
Metal bindingi | 126 | Iron-sulfur (4Fe-4S) 2By similarity | 1 | |
Metal bindingi | 129 | Iron-sulfur (4Fe-4S) 2By similarity | 1 | |
Metal bindingi | 141 | Iron-sulfur (4Fe-4S) 2By similarity | 1 | |
Metal bindingi | 145 | Iron-sulfur (4Fe-4S) 1By similarity | 1 |
GO - Molecular functioni
- 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- anaerobic respiration Source: ComplexPortal
Keywordsi
Biological process | Electron transport, Transport |
Ligand | 4Fe-4S, Iron, Iron-sulfur, Metal-binding |
Enzyme and pathway databases
BioCyci | EcoCyc:G6847-MONOMER |
Protein family/group databases
TCDBi | 5.A.3.3.1, the prokaryotic molybdopterin-containing oxidoreductase (pmo) family |
Names & Taxonomyi
Protein namesi | Recommended name: Probable anaerobic dimethyl sulfoxide reductase chain YnfGAlternative name(s): DMSO reductase iron-sulfur subunit YnfG |
Gene namesi | Name:ynfG Ordered Locus Names:b1589, JW1581 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedBy similarity | |||
ChainiPRO_0000159244 | 2 – 205 | Probable anaerobic dimethyl sulfoxide reductase chain YnfGAdd BLAST | 204 |
Proteomic databases
jPOSTi | P0AAJ1 |
PaxDbi | P0AAJ1 |
PRIDEi | P0AAJ1 |
Interactioni
Subunit structurei
The complex consists of three subunits: YnfF, the reductase; YnfG, an electron transfer protein, and YnfH, a membrane anchor protein.
CuratedProtein-protein interaction databases
BioGRIDi | 4263480, 23 interactors |
ComplexPortali | CPX-6019, Putative dimethyl sulfoxide reductase |
DIPi | DIP-48224N |
STRINGi | 511145.b1589 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 5 – 33 | 4Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd BLAST | 29 | |
Domaini | 59 – 89 | 4Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd BLAST | 31 | |
Domaini | 90 – 119 | 4Fe-4S ferredoxin-type 3PROSITE-ProRule annotationAdd BLAST | 30 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 183 – 205 | DisorderedSequence analysisAdd BLAST | 23 |
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | COG0437, Bacteria |
HOGENOMi | CLU_043374_2_0_6 |
InParanoidi | P0AAJ1 |
OMAi | CKYCSWS |
PhylomeDBi | P0AAJ1 |
Family and domain databases
InterProi | View protein in InterPro IPR017896, 4Fe4S_Fe-S-bd IPR017900, 4Fe4S_Fe_S_CS IPR014297, DMSO_DmsB |
Pfami | View protein in Pfam PF13247, Fer4_11, 1 hit PF12800, Fer4_4, 1 hit |
TIGRFAMsi | TIGR02951, DMSO_dmsB, 1 hit |
PROSITEi | View protein in PROSITE PS00198, 4FE4S_FER_1, 1 hit PS51379, 4FE4S_FER_2, 3 hits |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P0AAJ1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTTQYGFFID SSRCTGCKTC ELACKDFKDL GPEVSFRRIY EYAGGDWQED
60 70 80 90 100
NGVWHQNVFA YYLSISCNHC DDPACTKVCP SGAMHKREDG FVVVDEDVCI
110 120 130 140 150
GCRYCHMACP YGAPQYNAEK GHMTKCDGCY SRVAEGKQPI CVESCPLRAL
160 170 180 190 200
EFGPIEELRQ KHGTLAAVAP LPRAHFTKPN IVIKPNANSR PTGDTTGYLA
NPEEV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74661.1 AP009048 Genomic DNA Translation: BAA15313.1 |
PIRi | G64914 |
RefSeqi | NP_416106.1, NC_000913.3 WP_000213028.1, NZ_STEB01000003.1 |
Genome annotation databases
EnsemblBacteriai | AAC74661; AAC74661; b1589 BAA15313; BAA15313; BAA15313 |
GeneIDi | 66674521 945638 |
KEGGi | ecj:JW1581 eco:b1589 |
PATRICi | fig|1411691.4.peg.673 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74661.1 AP009048 Genomic DNA Translation: BAA15313.1 |
PIRi | G64914 |
RefSeqi | NP_416106.1, NC_000913.3 WP_000213028.1, NZ_STEB01000003.1 |
3D structure databases
AlphaFoldDBi | P0AAJ1 |
SMRi | P0AAJ1 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4263480, 23 interactors |
ComplexPortali | CPX-6019, Putative dimethyl sulfoxide reductase |
DIPi | DIP-48224N |
STRINGi | 511145.b1589 |
Protein family/group databases
TCDBi | 5.A.3.3.1, the prokaryotic molybdopterin-containing oxidoreductase (pmo) family |
Proteomic databases
jPOSTi | P0AAJ1 |
PaxDbi | P0AAJ1 |
PRIDEi | P0AAJ1 |
Genome annotation databases
EnsemblBacteriai | AAC74661; AAC74661; b1589 BAA15313; BAA15313; BAA15313 |
GeneIDi | 66674521 945638 |
KEGGi | ecj:JW1581 eco:b1589 |
PATRICi | fig|1411691.4.peg.673 |
Organism-specific databases
EchoBASEi | EB3606 |
Phylogenomic databases
eggNOGi | COG0437, Bacteria |
HOGENOMi | CLU_043374_2_0_6 |
InParanoidi | P0AAJ1 |
OMAi | CKYCSWS |
PhylomeDBi | P0AAJ1 |
Enzyme and pathway databases
BioCyci | EcoCyc:G6847-MONOMER |
Miscellaneous databases
PROi | PR:P0AAJ1 |
Family and domain databases
InterProi | View protein in InterPro IPR017896, 4Fe4S_Fe-S-bd IPR017900, 4Fe4S_Fe_S_CS IPR014297, DMSO_DmsB |
Pfami | View protein in Pfam PF13247, Fer4_11, 1 hit PF12800, Fer4_4, 1 hit |
TIGRFAMsi | TIGR02951, DMSO_dmsB, 1 hit |
PROSITEi | View protein in PROSITE PS00198, 4FE4S_FER_1, 1 hit PS51379, 4FE4S_FER_2, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | YNFG_ECOLI | |
Accessioni | P0AAJ1Primary (citable) accession number: P0AAJ1 Secondary accession number(s): P77313 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 11, 2005 |
Last sequence update: | January 23, 2007 | |
Last modified: | May 25, 2022 | |
This is version 114 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |