UniProtKB - P0AA99 (YAFK_ECOLI)
Protein
Putative L,D-transpeptidase YafK
Gene
yafK
Organism
Escherichia coli (strain K12)
Status
Functioni
: peptidoglycan biosynthesis Pathwayi
This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.
GO - Molecular functioni
- hydrolase activity Source: UniProtKB-KW
- transferase activity, transferring glycosyl groups Source: UniProtKB-KW
GO - Biological processi
- cell wall organization Source: UniProtKB-KW
- peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
- regulation of cell shape Source: UniProtKB-KW
Keywordsi
Molecular function | Glycosyltransferase, Hydrolase, Transferase |
Biological process | Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis |
Enzyme and pathway databases
BioCyci | EcoCyc:G6108-MONOMER |
UniPathwayi | UPA00219 |
Protein family/group databases
MEROPSi | C82.A01 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:yafK Ordered Locus Names:b0224, JW0214 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | Sequence analysisAdd BLAST | 19 | |
ChainiPRO_0000013784 | 20 – 246 | Putative L,D-transpeptidase YafKAdd BLAST | 227 |
Proteomic databases
PaxDbi | P0AA99 |
PRIDEi | P0AA99 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4262122, 20 interactors |
STRINGi | 511145.b0224 |
Family & Domainsi
Sequence similaritiesi
Belongs to the YkuD family.Curated
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | COG3034, Bacteria |
HOGENOMi | CLU_032558_2_0_6 |
InParanoidi | P0AA99 |
PhylomeDBi | P0AA99 |
Family and domain databases
CDDi | cd16913, YkuD_like, 1 hit |
InterProi | View protein in InterPro IPR005490, LD_TPept_cat_dom IPR038063, Transpep_catalytic_dom |
Pfami | View protein in Pfam PF03734, YkuD, 1 hit |
SUPFAMi | SSF141523, SSF141523, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P0AA99-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRKIALILAM LLIPCVSFAG LLGSSSSTTP VSKEYKQQLM GSPVYIQIFK
60 70 80 90 100
EERTLDLYVK MGEQYQLLDS YKICKYSGGL GPKQRQGDFK SPEGFYSVQR
110 120 130 140 150
NQLKPDSRYY KAINIGFPNA YDRAHGYEGK YLMIHGDCVS IGCYAMTNQG
160 170 180 190 200
IDEIFQFVTG ALVFGQPSVQ VSIYPFRMTD ANMKRHKYSN FKDFWEQLKP
210 220 230 240
GYDYFEQTRK PPTVSVVNGR YVVSKPLSHE VVQPQLASNY TLPEAK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D38582 Genomic DNA Translation: BAA07586.1 U70214 Genomic DNA Translation: AAB08646.1 U00096 Genomic DNA Translation: AAC73328.1 AP009048 Genomic DNA Translation: BAA77894.1 |
PIRi | A64747 |
RefSeqi | NP_414759.1, NC_000913.3 WP_001225679.1, NZ_STEB01000020.1 |
Genome annotation databases
EnsemblBacteriai | AAC73328; AAC73328; b0224 BAA77894; BAA77894; BAA77894 |
GeneIDi | 57728913 944910 |
KEGGi | ecj:JW0214 eco:b0224 |
PATRICi | fig|511145.12.peg.226 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D38582 Genomic DNA Translation: BAA07586.1 U70214 Genomic DNA Translation: AAB08646.1 U00096 Genomic DNA Translation: AAC73328.1 AP009048 Genomic DNA Translation: BAA77894.1 |
PIRi | A64747 |
RefSeqi | NP_414759.1, NC_000913.3 WP_001225679.1, NZ_STEB01000020.1 |
3D structure databases
SMRi | P0AA99 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4262122, 20 interactors |
STRINGi | 511145.b0224 |
Protein family/group databases
MEROPSi | C82.A01 |
Proteomic databases
PaxDbi | P0AA99 |
PRIDEi | P0AA99 |
Genome annotation databases
EnsemblBacteriai | AAC73328; AAC73328; b0224 BAA77894; BAA77894; BAA77894 |
GeneIDi | 57728913 944910 |
KEGGi | ecj:JW0214 eco:b0224 |
PATRICi | fig|511145.12.peg.226 |
Organism-specific databases
EchoBASEi | EB2942 |
Phylogenomic databases
eggNOGi | COG3034, Bacteria |
HOGENOMi | CLU_032558_2_0_6 |
InParanoidi | P0AA99 |
PhylomeDBi | P0AA99 |
Enzyme and pathway databases
UniPathwayi | UPA00219 |
BioCyci | EcoCyc:G6108-MONOMER |
Miscellaneous databases
PROi | PR:P0AA99 |
Family and domain databases
CDDi | cd16913, YkuD_like, 1 hit |
InterProi | View protein in InterPro IPR005490, LD_TPept_cat_dom IPR038063, Transpep_catalytic_dom |
Pfami | View protein in Pfam PF03734, YkuD, 1 hit |
SUPFAMi | SSF141523, SSF141523, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YAFK_ECOLI | |
Accessioni | P0AA99Primary (citable) accession number: P0AA99 Secondary accession number(s): Q47148 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 13, 2005 |
Last sequence update: | September 13, 2005 | |
Last modified: | April 7, 2021 | |
This is version 94 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families