UniProtKB - P0AA76 (DGOT_ECOLI)
Protein
D-galactonate transporter
Gene
dgoT
Organism
Escherichia coli (strain K12)
Status
Functioni
Intake of galactonate into the cell.
GO - Molecular functioni
- D-galactonate transmembrane transporter activity Source: EcoCyc
- solute:proton symporter activity Source: EcoCyc
GO - Biological processi
- D-galactonate catabolic process Source: EcoCyc
- D-galactonate transmembrane transport Source: EcoCyc
Keywordsi
Biological process | Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:YIDT-MONOMER MetaCyc:YIDT-MONOMER |
Protein family/group databases
TCDBi | 2.A.1.14.7, the major facilitator superfamily (mfs) |
Names & Taxonomyi
Protein namesi | Recommended name: D-galactonate transporter |
Gene namesi | Name:dgoT Synonyms:yidT Ordered Locus Names:b3691, JW5859 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 17 | PeriplasmicSequence analysisAdd BLAST | 17 | |
Transmembranei | 18 – 38 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 39 – 54 | CytoplasmicSequence analysisAdd BLAST | 16 | |
Transmembranei | 55 – 75 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 76 – 84 | PeriplasmicSequence analysis | 9 | |
Transmembranei | 85 – 105 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 106 – 142 | CytoplasmicSequence analysisAdd BLAST | 37 | |
Transmembranei | 143 – 163 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 164 – 167 | PeriplasmicSequence analysis | 4 | |
Transmembranei | 168 – 188 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 189 – 242 | CytoplasmicSequence analysisAdd BLAST | 54 | |
Transmembranei | 243 – 263 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 264 – 283 | PeriplasmicSequence analysisAdd BLAST | 20 | |
Transmembranei | 284 – 304 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 305 – 309 | CytoplasmicSequence analysis | 5 | |
Transmembranei | 310 – 330 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 331 – 337 | PeriplasmicSequence analysis | 7 | |
Transmembranei | 338 – 358 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 359 – 375 | CytoplasmicSequence analysisAdd BLAST | 17 | |
Transmembranei | 376 – 396 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 397 – 403 | PeriplasmicSequence analysis | 7 | |
Transmembranei | 404 – 424 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 425 – 430 | CytoplasmicSequence analysis | 6 |
GO - Cellular componenti
- integral component of plasma membrane Source: EcoCyc
- plasma membrane Source: EcoCyc
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000121377 | 1 – 430 | D-galactonate transporterAdd BLAST | 430 |
Proteomic databases
PaxDbi | P0AA76 |
PRIDEi | P0AA76 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4263278, 7 interactors |
DIPi | DIP-9436N |
STRINGi | 511145.b3691 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG2271, Bacteria |
HOGENOMi | CLU_001265_5_1_6 |
InParanoidi | P0AA76 |
PhylomeDBi | P0AA76 |
Family and domain databases
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
i Sequence
Sequence statusi: Complete.
P0AA76-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDIPVNAAKP GRRRYLTLVM IFITVVICYV DRANLAVASA HIQEEFGITK
60 70 80 90 100
AEMGYVFSAF AWLYTLCQIP GGWFLDRVGS RVTYFIAIFG WSVATLFQGF
110 120 130 140 150
ATGLMSLIGL RAITGIFEAP AFPTNNRMVT SWFPEHERAS AVGFYTSGQF
160 170 180 190 200
VGLAFLTPLL IWIQEMLSWH WVFIVTGGIG IIWSLIWFKV YQPPRLTKGI
210 220 230 240 250
SKAELDYIRD GGGLVDGDAP VKKEARQPLT AKDWKLVFHR KLIGVYLGQF
260 270 280 290 300
AVASTLWFFL TWFPNYLTQE KGITALKAGF MTTVPFLAAF VGVLLSGWVA
310 320 330 340 350
DLLVRKGFSL GFARKTPIIC GLLISTCIMG ANYTNDPMMI MCLMALAFFG
360 370 380 390 400
NGFASITWSL VSSLAPMRLI GLTGGVFNFA GGLGGITVPL VVGYLAQGYG
410 420 430
FAPALVYISA VALIGALSYI LLVGDVKRVG
Sequence cautioni
The sequence AAA62043 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L10328 Genomic DNA Translation: AAA62043.1 Different initiation. U00096 Genomic DNA Translation: AAC76714.2 AP009048 Genomic DNA Translation: BAE77603.1 |
PIRi | D65171 |
RefSeqi | NP_418146.4, NC_000913.3 |
Genome annotation databases
EnsemblBacteriai | AAC76714; AAC76714; b3691 BAE77603; BAE77603; BAE77603 |
GeneIDi | 948196 |
KEGGi | ecj:JW5859 eco:b3691 |
PATRICi | fig|511145.12.peg.3814 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L10328 Genomic DNA Translation: AAA62043.1 Different initiation. U00096 Genomic DNA Translation: AAC76714.2 AP009048 Genomic DNA Translation: BAE77603.1 |
PIRi | D65171 |
RefSeqi | NP_418146.4, NC_000913.3 |
3D structure databases
SMRi | P0AA76 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4263278, 7 interactors |
DIPi | DIP-9436N |
STRINGi | 511145.b3691 |
Protein family/group databases
TCDBi | 2.A.1.14.7, the major facilitator superfamily (mfs) |
Proteomic databases
PaxDbi | P0AA76 |
PRIDEi | P0AA76 |
Genome annotation databases
EnsemblBacteriai | AAC76714; AAC76714; b3691 BAE77603; BAE77603; BAE77603 |
GeneIDi | 948196 |
KEGGi | ecj:JW5859 eco:b3691 |
PATRICi | fig|511145.12.peg.3814 |
Organism-specific databases
EchoBASEi | EB1666 |
Phylogenomic databases
eggNOGi | COG2271, Bacteria |
HOGENOMi | CLU_001265_5_1_6 |
InParanoidi | P0AA76 |
PhylomeDBi | P0AA76 |
Enzyme and pathway databases
BioCyci | EcoCyc:YIDT-MONOMER MetaCyc:YIDT-MONOMER |
Miscellaneous databases
PROi | PR:P0AA76 |
Family and domain databases
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DGOT_ECOLI | |
Accessioni | P0AA76Primary (citable) accession number: P0AA76 Secondary accession number(s): P31457, Q2M803 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 13, 2005 |
Last sequence update: | September 13, 2005 | |
Last modified: | December 2, 2020 | |
This is version 111 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families