UniProtKB - P0AA70 (YEDA_ECOLI)
Protein
Uncharacterized inner membrane transporter YedA
Gene
yedA
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Biological processi
- response to toxic substance Source: EcoCyc
Keywordsi
Biological process | Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11141-MONOMER |
Protein family/group databases
TCDBi | 2.A.7.3.22, the drug/metabolite transporter (dmt) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized inner membrane transporter YedA |
Gene namesi | Name:yedA Ordered Locus Names:b1959, JW1942 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
Plasma Membrane
- integral component of plasma membrane Source: EcoCyc
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 6 | CytoplasmicSequence analysis | 6 | |
Transmembranei | 7 – 27 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 28 – 36 | PeriplasmicSequence analysis | 9 | |
Transmembranei | 37 – 57 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 58 – 67 | CytoplasmicSequence analysis | 10 | |
Transmembranei | 68 – 88 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 89 – 93 | PeriplasmicSequence analysis | 5 | |
Transmembranei | 94 – 114 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 115 – 125 | CytoplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 126 – 146 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 147 – 148 | PeriplasmicSequence analysis | 2 | |
Transmembranei | 149 – 169 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 170 – 173 | CytoplasmicSequence analysis | 4 | |
Transmembranei | 174 – 194 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 195 – 206 | PeriplasmicSequence analysisAdd BLAST | 12 | |
Transmembranei | 207 – 227 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 228 – 239 | CytoplasmicSequence analysisAdd BLAST | 12 | |
Transmembranei | 240 – 260 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 261 – 269 | PeriplasmicSequence analysis | 9 | |
Transmembranei | 270 – 290 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 291 – 306 | CytoplasmicSequence analysisAdd BLAST | 16 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000108166 | 1 – 306 | Uncharacterized inner membrane transporter YedAAdd BLAST | 306 |
Proteomic databases
PaxDbi | P0AA70 |
PRIDEi | P0AA70 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4261055, 9 interactors |
STRINGi | 511145.b1959 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 18 – 141 | EamA 1Add BLAST | 124 | |
Domaini | 160 – 285 | EamA 2Add BLAST | 126 |
Sequence similaritiesi
Belongs to the EamA transporter family.Curated
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG0697, Bacteria |
HOGENOMi | CLU_033863_5_1_6 |
InParanoidi | P0AA70 |
PhylomeDBi | P0AA70 |
Family and domain databases
InterProi | View protein in InterPro IPR004779, CO/AA/NH_transpt IPR000620, EamA_dom |
Pfami | View protein in Pfam PF00892, EamA, 2 hits |
TIGRFAMsi | TIGR00950, 2A78, 1 hit |
i Sequence
Sequence statusi: Complete.
P0AA70-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRFRQLLPLF GALFALYIIW GSTYFVIRIG VESWPPLMMA GVRFLAAGIL
60 70 80 90 100
LLAFLLLRGH KLPPLRPLLN AALIGLLLLA VGNGMVTVAE HQNVPSGIAA
110 120 130 140 150
VVVATVPLFT LCFSRLFGIK TRKLEWVGIA IGLAGIIMLN SGGNLSGNPW
160 170 180 190 200
GAILILIGSI SWAFGSVYGS RITLPVGMMA GAIEMLAAGV VLMIASMIAG
210 220 230 240 250
EKLTALPSLS GFLAVGYLAL FGSIIAINAY MYLIRNVSPA LATSYAYVNP
260 270 280 290 300
VVAVLLGTGL GGETLSKIEW LALGVIVFAV VLVTLGKYLF PAKPVVAPVI
QDASSE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X13330 Genomic DNA Translation: CAA31708.1 U00096 Genomic DNA Translation: AAC75025.1 AP009048 Genomic DNA Translation: BAA15786.1 |
PIRi | JS0266 |
RefSeqi | NP_416468.1, NC_000913.3 WP_001212226.1, NZ_SSUR01000050.1 |
Genome annotation databases
EnsemblBacteriai | AAC75025; AAC75025; b1959 BAA15786; BAA15786; BAA15786 |
GeneIDi | 946461 |
KEGGi | ecj:JW1942 eco:b1959 |
PATRICi | fig|1411691.4.peg.293 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X13330 Genomic DNA Translation: CAA31708.1 U00096 Genomic DNA Translation: AAC75025.1 AP009048 Genomic DNA Translation: BAA15786.1 |
PIRi | JS0266 |
RefSeqi | NP_416468.1, NC_000913.3 WP_001212226.1, NZ_SSUR01000050.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4261055, 9 interactors |
STRINGi | 511145.b1959 |
Protein family/group databases
TCDBi | 2.A.7.3.22, the drug/metabolite transporter (dmt) superfamily |
Proteomic databases
PaxDbi | P0AA70 |
PRIDEi | P0AA70 |
Genome annotation databases
EnsemblBacteriai | AAC75025; AAC75025; b1959 BAA15786; BAA15786; BAA15786 |
GeneIDi | 946461 |
KEGGi | ecj:JW1942 eco:b1959 |
PATRICi | fig|1411691.4.peg.293 |
Organism-specific databases
EchoBASEi | EB1131 |
Phylogenomic databases
eggNOGi | COG0697, Bacteria |
HOGENOMi | CLU_033863_5_1_6 |
InParanoidi | P0AA70 |
PhylomeDBi | P0AA70 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11141-MONOMER |
Miscellaneous databases
PROi | PR:P0AA70 |
Family and domain databases
InterProi | View protein in InterPro IPR004779, CO/AA/NH_transpt IPR000620, EamA_dom |
Pfami | View protein in Pfam PF00892, EamA, 2 hits |
TIGRFAMsi | TIGR00950, 2A78, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YEDA_ECOLI | |
Accessioni | P0AA70Primary (citable) accession number: P0AA70 Secondary accession number(s): P09185 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 13, 2005 |
Last sequence update: | September 13, 2005 | |
Last modified: | February 10, 2021 | |
This is version 107 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families