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UniProtKB - P0A9Y6 (CSPC_ECOLI)
Protein
Cold shock-like protein CspC
Gene
cspC
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Molecular functioni
- chaperone binding Source: CACAO
- nucleic acid binding Source: GO_Central
- RNA binding Source: EcoliWiki
- single-stranded DNA binding Source: EcoliWiki
- transcription antitermination factor activity, RNA binding Source: EcoliWiki
GO - Biological processi
- negative regulation of DNA-templated transcription, termination Source: EcoliWiki
- regulation of gene expression Source: GO_Central
Keywordsi
Molecular function | Activator, DNA-binding |
Biological process | Transcription, Transcription regulation |
Enzyme and pathway databases
BioCyci | EcoCyc:EG12204-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Cold shock-like protein CspCShort name: CSP-C |
Gene namesi | Name:cspC Synonyms:msmB Ordered Locus Names:b1823, JW1812 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm By similarity
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | Removed3 Publications | |||
ChainiPRO_0000100241 | 2 – 69 | Cold shock-like protein CspCAdd BLAST | 68 |
Proteomic databases
jPOSTi | P0A9Y6 |
PaxDbi | P0A9Y6 |
PRIDEi | P0A9Y6 |
2D gel databases
SWISS-2DPAGEi | P0A9Y6 |
Interactioni
GO - Molecular functioni
- chaperone binding Source: CACAO
Protein-protein interaction databases
BioGRIDi | 4263536, 354 interactors 850696, 1 interactor |
DIPi | DIP-36183N |
IntActi | P0A9Y6, 77 interactors |
STRINGi | 511145.b1823 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 6 – 66 | CSDAdd BLAST | 61 |
Phylogenomic databases
eggNOGi | COG1278, Bacteria |
HOGENOMi | CLU_117621_2_1_6 |
InParanoidi | P0A9Y6 |
OMAi | FEIQDGH |
PhylomeDBi | P0A9Y6 |
Family and domain databases
CDDi | cd04458, CSP_CDS, 1 hit |
Gene3Di | 2.40.50.140, 1 hit |
InterProi | View protein in InterPro IPR012156, Cold_shock_CspA IPR011129, CSD IPR019844, CSD_1 IPR002059, CSP_DNA-bd IPR012340, NA-bd_OB-fold |
Pfami | View protein in Pfam PF00313, CSD, 1 hit |
PIRSFi | PIRSF002599, Cold_shock_A, 1 hit |
PRINTSi | PR00050, COLDSHOCK |
SMARTi | View protein in SMART SM00357, CSP, 1 hit |
SUPFAMi | SSF50249, SSF50249, 1 hit |
PROSITEi | View protein in PROSITE PS00352, CSD_1, 1 hit PS51857, CSD_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P0A9Y6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKIKGQVKW FNESKGFGFI TPADGSKDVF VHFSAIQGNG FKTLAEGQNV
60
EFEIQDGQKG PAAVNVTAI
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 7 | Q → T AA sequence (PubMed:9868784).Curated | 1 |
Mass spectrometryi
Molecular mass is 7273 Da. Determined by ESI. 1 Publication
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L28430 Genomic DNA Translation: AAA23619.1 D28496 Genomic DNA Translation: BAA05854.1 U00096 Genomic DNA Translation: AAC74893.1 AP009048 Genomic DNA Translation: BAA15634.1 |
PIRi | S43618 |
RefSeqi | NP_416337.1, NC_000913.3 WP_001062678.1, NZ_STEB01000009.1 |
Genome annotation databases
EnsemblBacteriai | AAC74893; AAC74893; b1823 BAA15634; BAA15634; BAA15634 |
GeneIDi | 8911702 946339 |
KEGGi | ecj:JW1812 eco:b1823 |
PATRICi | fig|1411691.4.peg.428 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L28430 Genomic DNA Translation: AAA23619.1 D28496 Genomic DNA Translation: BAA05854.1 U00096 Genomic DNA Translation: AAC74893.1 AP009048 Genomic DNA Translation: BAA15634.1 |
PIRi | S43618 |
RefSeqi | NP_416337.1, NC_000913.3 WP_001062678.1, NZ_STEB01000009.1 |
3D structure databases
AlphaFoldDBi | P0A9Y6 |
SMRi | P0A9Y6 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4263536, 354 interactors 850696, 1 interactor |
DIPi | DIP-36183N |
IntActi | P0A9Y6, 77 interactors |
STRINGi | 511145.b1823 |
2D gel databases
SWISS-2DPAGEi | P0A9Y6 |
Proteomic databases
jPOSTi | P0A9Y6 |
PaxDbi | P0A9Y6 |
PRIDEi | P0A9Y6 |
Genome annotation databases
EnsemblBacteriai | AAC74893; AAC74893; b1823 BAA15634; BAA15634; BAA15634 |
GeneIDi | 8911702 946339 |
KEGGi | ecj:JW1812 eco:b1823 |
PATRICi | fig|1411691.4.peg.428 |
Organism-specific databases
EchoBASEi | EB2120 |
Phylogenomic databases
eggNOGi | COG1278, Bacteria |
HOGENOMi | CLU_117621_2_1_6 |
InParanoidi | P0A9Y6 |
OMAi | FEIQDGH |
PhylomeDBi | P0A9Y6 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG12204-MONOMER |
Miscellaneous databases
PROi | PR:P0A9Y6 |
Family and domain databases
CDDi | cd04458, CSP_CDS, 1 hit |
Gene3Di | 2.40.50.140, 1 hit |
InterProi | View protein in InterPro IPR012156, Cold_shock_CspA IPR011129, CSD IPR019844, CSD_1 IPR002059, CSP_DNA-bd IPR012340, NA-bd_OB-fold |
Pfami | View protein in Pfam PF00313, CSD, 1 hit |
PIRSFi | PIRSF002599, Cold_shock_A, 1 hit |
PRINTSi | PR00050, COLDSHOCK |
SMARTi | View protein in SMART SM00357, CSP, 1 hit |
SUPFAMi | SSF50249, SSF50249, 1 hit |
PROSITEi | View protein in PROSITE PS00352, CSD_1, 1 hit PS51857, CSD_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | CSPC_ECOLI | |
Accessioni | P0A9Y6Primary (citable) accession number: P0A9Y6 Secondary accession number(s): O68636, P36996 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 13, 2005 |
Last sequence update: | January 23, 2007 | |
Last modified: | May 25, 2022 | |
This is version 115 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |